| Hyperactivation of HUSH complex function by Charcot–Marie–Tooth disease mutation in MORC2 IA Tchasovnikarova, RT Timms, CH Douse, RC Roberts, G Dougan, ... Nature genetics 49 (7), 1035-1044, 2017 | 142 | 2017 |
| TASOR is a pseudo-PARP that directs HUSH complex assembly and epigenetic transposon control CH Douse, IA Tchasovnikarova, RT Timms, AV Protasio, M Seczynska, ... Nature communications 11 (1), 4940, 2020 | 84 | 2020 |
| Neuropathic MORC2 mutations perturb GHKL ATPase dimerization dynamics and epigenetic silencing by multiple structural mechanisms CH Douse, S Bloor, Y Liu, M Shamin, IA Tchasovnikarova, RT Timms, ... Nature communications 9 (1), 651, 2018 | 84 | 2018 |
| Crystal structures of stapled and hydrogen bond surrogate peptides targeting a fully buried protein–helix interaction CH Douse, SJ Maas, JC Thomas, JA Garnett, Y Sun, E Cota, EW Tate ACS Chemical Biology 9 (10), 2204-2209, 2014 | 64 | 2014 |
| A cis-acting structural variation at the ZNF558 locus controls a gene regulatory network in human brain development PA Johansson, PL Brattås, CH Douse, PH Hsieh, A Adami, J Pontis, ... Cell stem cell 29 (1), 52-69. e8, 2022 | 42 | 2022 |
| The Plasmodium class XIV myosin, MyoB, has a distinct subcellular location in invasive and motile stages of the malaria parasite and an unusual light chain NA Yusuf, JL Green, RJ Wall, E Knuepfer, RW Moon, C Schulte-Huxel, ... Journal of Biological Chemistry 290 (19), 12147-12164, 2015 | 39 | 2015 |
| Regulation of the Plasmodium motor complex: phosphorylation of myosin A tail-interacting protein (MTIP) loosens its grip on MyoA CH Douse, JL Green, PS Salgado, PJ Simpson, JC Thomas, G Langsley, ... Journal of Biological Chemistry 287 (44), 36968-36977, 2012 | 36 | 2012 |
| Targeting a dynamic protein–protein interaction: fragment screening against the malaria myosin A motor complex CH Douse, N Vrielink, Z Wenlin, E Cota, EW Tate ChemMedChem 10 (1), 134-143, 2015 | 30 | 2015 |
| Periphilin self-association underpins epigenetic silencing by the HUSH complex DM Prigozhin, CH Douse, LE Farleigh, A Albecka, IA Tchasovnikarova, ... Nucleic Acids Research 48 (18), 10313-10328, 2020 | 27 | 2020 |
| LINE-1 retrotransposons drive human neuronal transcriptome complexity and functional diversification R Garza, DAM Atacho, A Adami, P Gerdes, M Vinod, PH Hsieh, ... Science Advances 9 (44), eadh9543, 2023 | 25 | 2023 |
| Structure and functional mapping of the KRAB‐KAP1 repressor complex GA Stoll, N Pandiloski, CH Douse, Y Modis The EMBO Journal 41 (24), e111179, 2022 | 20 | 2022 |
| The annotation of GBA1 has been concealed by its protein-coding pseudogene GBAP1 EK Gustavsson, S Sethi, Y Gao, JW Brenton, S García-Ruiz, D Zhang, ... Science Advances 10 (26), eadk1296, 2024 | 12* | 2024 |
| Structure–function analysis reveals that the Pseudomonas aeruginosa Tps4 two‐partner secretion system is involved in CupB5 translocation JA Garnett, D Muhl, CH Douse, K Hui, A Busch, A Omisore, Y Yang, ... Protein Science 24 (5), 670-687, 2015 | 10 | 2015 |
| The DUF3715 domain has a conserved role in RNA-directed transposon silencing T Schöpp, DM Prigozhin, C Douse, K Kaji, AG Cook, D O'Carroll Rna 29 (10), 1471-1480, 2023 | 5 | 2023 |
| DNA methylation governs the sensitivity of repeats to restriction by the HUSH-MORC2 corepressor N Pandiloski, V Horváth, O Karlsson, S Koutounidou, F Dorazehi, ... Nature communications 15 (1), 7534, 2024 | 4 | 2024 |
| Mini-heterochromatin domains constrain the cis-regulatory impact of SVA transposons in human brain development and disease V Horváth, R Garza, ME Jönsson, PA Johansson, A Adami, ... Nature Structural & Molecular Biology, 1-14, 2024 | 4 | 2024 |
| A human-specific structural variation at the ZNF558 locus controls a gene regulatory network during forebrain development PA Johansson, PL Brattås, CH Douse, PH Hsieh, J Pontis, D Grassi, ... bioRxiv, 2020.08. 18.255562, 2020 | 4 | 2020 |
| Crystal structure and biochemical activity of the macrodomain from rubella virus p150 GA Stoll, N Nikolopoulos, H Zhai, L Zhang, CH Douse, Y Modis Journal of virology 98 (2), e01777-23, 2024 | | 2024 |
| Crystal structure and biochemical activity of the macrodomain from rubella virus p150 Y Modis, H Zhai, L Zhang, C Douse American Society for Microbiology, 2024 | | 2024 |
| Neuropathic mutations in MORC2 perturb GHKL ATPase dimerization dynamics and epigenetic silencing by multiple structural mechanisms CH Douse, S Bloor, Y Liu, M Shamin, IA Tchasovnikarova, RT Timms, ... bioRxiv, 197186, 2017 | | 2017 |
