Steven J Howe
Title
Cited by
Cited by
Year
Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients
SJ Howe, MR Mansour, K Schwarzwaelder, C Bartholomae, M Hubank, ...
The Journal of clinical investigation 118 (9), 2008
11732008
Gene therapy of X-linked severe combined immunodeficiency by use of a pseudotyped gammaretroviral vector
HB Gaspar, KL Parsley, S Howe, D King, KC Gilmour, J Sinclair, G Brouns, ...
The Lancet 364 (9452), 2181-2187, 2004
7442004
Effective gene therapy with nonintegrating lentiviral vectors
RJ YŠnez-Munoz, KS Balaggan, A MacNeil, SJ Howe, M Schmidt, ...
Nature medicine 12 (3), 348-353, 2006
5102006
Hot spots of retroviral integration in human CD34+ hematopoietic cells
C Cattoglio, G Facchini, D Sartori, A Antonelli, A Miccio, B Cassani, ...
Blood 110 (6), 1770-1778, 2007
3002007
Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy
A Deichmann, S Hacein-Bey-Abina, M Schmidt, A Garrigue, MH Brugman, ...
The Journal of clinical investigation 117 (8), 2225-2232, 2007
2732007
Long-term persistence of a polyclonal T cell repertoire after gene therapy for X-linked severe combined immunodeficiency
HB Gaspar, S Cooray, KC Gilmour, KL Parsley, S Adams, SJ Howe, ...
Science translational medicine 3 (97), 97ra79-97ra79, 2011
2362011
Long-term persistence of a polyclonal T cell repertoire after gene therapy for X-linked severe combined immunodeficiency
HB Gaspar, S Cooray, KC Gilmour, KL Parsley, S Adams, SJ Howe, ...
Science translational medicine 3 (97), 97ra79-97ra79, 2011
2362011
System and method for controlling access to location information
HS Bhela, SL Lawler, RM Rao
US Patent 7,224,987, 2007
2302007
Gammaretrovirus-mediated correction of SCID-X1 is associated with skewed vector integration site distribution in vivo
K Schwarzwaelder, SJ Howe, M Schmidt, MH Brugman, A Deichmann, ...
The Journal of clinical investigation 117 (8), 2241-2249, 2007
2272007
Lentiviral vectors containing an enhancer-less ubiquitously acting chromatin opening element (UCOE) provide highly reproducible and stable transgene expression in hematopoietic†…
F Zhang, SI Thornhill, SJ Howe, M Ulaganathan, A Schambach, J Sinclair, ...
Blood, The Journal of the American Society of Hematology 110 (5), 1448-1457, 2007
2072007
Comprehensive genomic access to vector integration in clinical gene therapy
R Gabriel, R Eckenberg, A Paruzynski, CC Bartholomae, A Nowrouzi, ...
Nature medicine 15 (12), 1431-1436, 2009
1792009
Self-inactivating gammaretroviral vectors for gene therapy of X-linked severe combined immunodeficiency
SI Thornhill, A Schambach, SJ Howe, M Ulaganathan, E Grassman, ...
Molecular therapy 16 (3), 590-598, 2008
1652008
Long-term preservation of retinal function in the RCS rat model of retinitis pigmentosa following lentivirus-mediated gene therapy
M Tschernutter, FC Schlichtenbrede, S Howe, KS Balaggan, PM Munro, ...
Gene therapy 12 (8), 694-701, 2005
1562005
Failure of SCID-X1 gene therapy in older patients
AJ Thrasher, S Hacein-Bey-Abina, HB Gaspar, S Blanche, EG Davies, ...
Blood 105 (11), 4255-4257, 2005
1282005
Persistent episomal transgene expression in liver following delivery of a scaffold/matrix attachment region containing non-viral vector
O Argyros, SP Wong, M Niceta, SN Waddington, SJ Howe, C Coutelle, ...
Gene therapy 15 (24), 1593-1605, 2008
1052008
Efficient gene delivery to the adult and fetal CNS using pseudotyped non-integrating lentiviral vectors
AA Rahim, AMS Wong, SJ Howe, SMK Buckley, AD Acosta-Saltos, ...
Gene therapy 16 (4), 509-520, 2009
1012009
Hematopoietic stem cell and gene therapy corrects primary neuropathology and behavior in mucopolysaccharidosis IIIA mice
A Langford-Smith, FL Wilkinson, KJ Langford-Smith, RJ Holley, ...
Molecular Therapy 20 (8), 1610-1621, 2012
952012
Ectopic retroviral expression of LMO2, but not IL2R γ, blocks human T-cell development from CD34+ cells: implications for leukemogenesis in gene therapy
K Pike-Overzet, D de Ridder, F Weerkamp, MRM Baert, MMA Verstegen, ...
Leukemia 21 (4), 754-763, 2007
842007
Retrovirus and lentivirus vector design and methods of cell conditioning
S Cooray, SJ Howe, AJ Thrasher
Methods in enzymology 507, 29-57, 2012
822012
Development of S/MAR minicircles for enhanced and persistent transgene expression in the mouse liver
O Argyros, SP Wong, C Fedonidis, O Tolmachov, SN Waddington, ...
Journal of molecular medicine 89 (5), 515-529, 2011
722011
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