Comprehensive molecular portraits of human breast tumours Brigham & Women’s Hospital & Harvard Medical School Chin Lynda 9 11 Park ... Nature 490 (7418), 61-70, 2012 | 11473 | 2012 |
Comprehensive molecular characterization of human colon and rectal cancer Cancer Genome Atlas Network Nature 487 (7407), 330, 2012 | 7762 | 2012 |
Comprehensive genomic characterization of squamous cell lung cancers Cancer Genome Atlas Research Network Nature 489 (7417), 519, 2012 | 3787 | 2012 |
Massive genomic rearrangement acquired in a single catastrophic event during cancer development PJ Stephens, CD Greenman, B Fu, F Yang, GR Bignell, LJ Mudie, ... cell 144 (1), 27-40, 2011 | 2685 | 2011 |
A comprehensive catalogue of somatic mutations from a human cancer genome ED Pleasance, RK Cheetham, PJ Stephens, DJ McBride, SJ Humphray, ... Nature 463 (7278), 191-196, 2010 | 2061 | 2010 |
The patterns and dynamics of genomic instability in metastatic pancreatic cancer PJ Campbell, S Yachida, LJ Mudie, PJ Stephens, ED Pleasance, ... Nature 467 (7319), 1109-1113, 2010 | 1588 | 2010 |
Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes GL Dalgliesh, K Furge, C Greenman, L Chen, G Bignell, A Butler, ... Nature 463 (7279), 360-363, 2010 | 1384 | 2010 |
A small-cell lung cancer genome with complex signatures of tobacco exposure ED Pleasance, PJ Stephens, S O’Meara, DJ McBride, A Meynert, D Jones, ... Nature 463 (7278), 184-190, 2010 | 1313 | 2010 |
Complex landscapes of somatic rearrangement in human breast cancer genomes PJ Stephens, DJ McBride, ML Lin, I Varela, ED Pleasance, JT Simpson, ... Nature 462 (7276), 1005-1010, 2009 | 1023 | 2009 |
Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing PJ Campbell, PJ Stephens, ED Pleasance, S O'Meara, H Li, T Santarius, ... Nature genetics 40 (6), 722-729, 2008 | 991 | 2008 |
Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer G Van Haaften, GL Dalgliesh, H Davies, L Chen, G Bignell, C Greenman, ... Nature genetics 41 (5), 521-523, 2009 | 938 | 2009 |
A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation PS Tarpey, R Smith, E Pleasance, A Whibley, S Edkins, C Hardy, ... Nature genetics 41 (5), 535-543, 2009 | 703 | 2009 |
Subclonal phylogenetic structures in cancer revealed by ultra-deep sequencing PJ Campbell, ED Pleasance, PJ Stephens, E Dicks, R Rance, I Goodhead, ... Proceedings of the National Academy of Sciences 105 (35), 13081-13086, 2008 | 507 | 2008 |
Mutational and structural analysis of diffuse large B-cell lymphoma using whole-genome sequencing RD Morin, K Mungall, E Pleasance, AJ Mungall, R Goya, RD Huff, ... Blood, The Journal of the American Society of Hematology 122 (7), 1256-1265, 2013 | 471 | 2013 |
A SAGE approach to discovery of genes involved in autophagic cell death SM Gorski, S Chittaranjan, ED Pleasance, JD Freeman, CL Anderson, ... Current Biology 13 (4), 358-363, 2003 | 280 | 2003 |
Architectures of somatic genomic rearrangement in human cancer amplicons at sequence-level resolution GR Bignell, T Santarius, JCM Pole, AP Butler, J Perry, E Pleasance, ... Genome research 17 (9), 1296-1303, 2007 | 234 | 2007 |
Homologous recombination deficiency and platinum-based therapy outcomes in advanced breast cancer EY Zhao, Y Shen, E Pleasance, K Kasaian, S Leelakumari, M Jones, ... Clinical Cancer Research 23 (24), 7521-7530, 2017 | 184 | 2017 |
NRG1 Gene Fusions Are Recurrent, Clinically Actionable Gene Rearrangements in KRAS Wild-Type Pancreatic Ductal Adenocarcinoma MR Jones, LM Williamson, JT Topham, MKC Lee, A Goytain, J Ho, ... Clinical Cancer Research 25 (15), 4674-4681, 2019 | 154 | 2019 |
ORegAnno: an open access database and curation system for literature-derived promoters, transcription factor binding sites and regulatory variation SB Montgomery, OL Griffith, MC Sleumer, CM Bergman, M Bilenky, ... Bioinformatics 22 (5), 637-640, 2006 | 154 | 2006 |
Estimation of rearrangement phylogeny for cancer genomes CD Greenman, ED Pleasance, S Newman, F Yang, B Fu, S Nik-Zainal, ... Genome research 22 (2), 346-361, 2012 | 141 | 2012 |