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Agnes Leffler
Agnes Leffler
Senior Research Scientist, RIA iMed, AstraZeneca
Verified email at astrazeneca.com
Title
Cited by
Cited by
Year
Benzoxazepines Achieve Potent Suppression of IL‐17 Release in Human T‐Helper 17 (TH17) Cells through an Induced‐Fit Binding Mode to the Nuclear …
RI Olsson, Y Xue, S von Berg, A Aagaard, J McPheat, EL Hansson, ...
ChemMedChem 11 (2), 207-216, 2016
632016
Characterization of species-related differences in the pharmacology of tachykinin NK receptors 1, 2 and 3
A Leffler, I Ahlstedt, S Engberg, A Svensson, M Billger, L Öberg, ...
Biochemical pharmacology 77 (9), 1522-1530, 2009
432009
Potent and orally bioavailable inverse agonists of RORγt resulting from structure-based design
F Narjes, Y Xue, S von Berg, J Malmberg, A Llinas, RI Olsson, J Jirholt, ...
Journal of Medicinal Chemistry 61 (17), 7796-7813, 2018
342018
Molecular cloning, mutations and effects of NK1 receptor antagonists reveal the human-like pharmacology of gerbil NK1 receptors
S Engberg, I Ahlstedt, A Leffler, E Lindström, E Kristensson, A Svensson, ...
Biochemical pharmacology 73 (2), 259-269, 2007
232007
Characterization of selective and potent JAK1 inhibitors intended for the inhaled treatment of asthma
M Nilsson, M Rhedin, R Hendrickx, S Berglund, A Piras, P Blomgran, ...
Drug design, development and therapy, 2901-2917, 2023
182023
Senktide-induced gerbil foot tapping behaviour is blocked by selective tachykinin NK1 and NK3 receptor antagonists
M Sundqvist, E Kristensson, R Adolfsson, A Leffler, I Ahlstedt, S Engberg, ...
European journal of pharmacology 577 (1-3), 78-86, 2007
142007
AZD0284, a potent, selective, and orally bioavailable inverse agonist of retinoic acid receptor-related orphan receptor C2
F Narjes, A Llinas, S von Berg, J Jirholt, S Lever, R Pehrson, M Collins, ...
Journal of Medicinal Chemistry 64 (18), 13807-13829, 2021
122021
Back Cover: Benzoxazepines Achieve Potent Suppression of IL‐17 Release in Human T‐Helper 17 (TH17) Cells through an Induced‐Fit Binding Mode to the …
RI Olsson, Y Xue, S von Berg, A Aagaard, J McPheat, EL Hansson, ...
ChemMedChem 11 (2), 245-245, 2016
2016
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