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Giedrius Sasnauskas
Giedrius Sasnauskas
Life Sciences Center, Vilnius University
Verified email at bti.vu.lt
Title
Cited by
Cited by
Year
Structure of the tetrameric restriction endonuclease NgoMIV in complex with cleaved DNA
M Deibert, S Grazulis, G Sasnauskas, V Siksnys, R Huber
nature structural biology 7 (9), 792-799, 2000
2002000
Novel Subtype of Type IIs Restriction Enzymes: BfiI endonuclease exhibits similarities to the EDTA-resistant nuclease Nuc of Salmonella typhimurium
R Sapranauskas, G Sasnauskas, A Lagunavicius, G Vilkaitis, A Lubys, ...
Journal of Biological Chemistry 275 (40), 30878-30885, 2000
1192000
The Cfr10I restriction enzyme is functional as a tetramer
V Siksnys, R Skirgaila, G Sasnauskas, C Urbanke, D Cherny, S Grazulis, ...
Journal of molecular biology 291 (5), 1105-1118, 1999
1051999
Generation and characterization of new highly thermostable and processive M-MuLV reverse transcriptase variants
A Baranauskas, S Paliksa, G Alzbutas, M Vaitkevicius, J Lubiene, ...
Protein Engineering, Design & Selection 25 (10), 657-668, 2012
852012
The metal-independent type IIs restriction enzyme BfiI is a dimer that binds two DNA sites but has only one catalytic centre
A Lagunavicius, G Sasnauskas, SE Halford, V Siksnys
Journal of molecular biology 326 (4), 1051-1064, 2003
802003
Crystal structure of the Bse634I restriction endonuclease: comparison of two enzymes recognizing the same DNA sequence
S Grazulis, M Deibert, R Rimseliene, R Skirgaila, G Sasnauskas, ...
Nucleic acids research 30 (4), 876-885, 2002
722002
How the BfiI restriction enzyme uses one active site to cut two DNA strands
G Sasnauskas, SE Halford, V Siksnys
Proceedings of the National Academy of Sciences 100 (11), 6410-6415, 2003
682003
TnpB structure reveals minimal functional core of Cas12 nuclease family
G Sasnauskas, G Tamulaitiene, G Druteika, A Carabias, A Silanskas, ...
Nature 616 (7956), 384-389, 2023
522023
Conversion of the tetrameric restriction endonuclease Bse634I into a dimer: oligomeric structure–stability–function correlations
M Zaremba, G Sasnauskas, C Urbanke, V Siksnys
Journal of molecular biology 348 (2), 459-478, 2005
462005
A novel mechanism for the scission of double-stranded DNA: BfiI cuts both 3′–5′ and 5′–3′ strands by rotating a single active site
G Sasnauskas, L Zakrys, M Zaremba, R Cosstick, JW Gaynor, SE Halford, ...
Nucleic acids research 38 (7), 2399-2410, 2010
432010
Plasmid DNA Cleavage by MunI Restriction Enzyme:  Single-Turnover and Steady-State Kinetic Analysis
G Sasnauskas, A Jeltsch, A Pingoud, V Siksnys
Biochemistry 38 (13), 4028-4036, 1999
401999
HEPN-MNT toxin-antitoxin system: the HEPN ribonuclease is neutralized by OligoAMPylation
I Songailiene, J Juozapaitis, G Tamulaitiene, A Ruksenaite, S Šulčius, ...
Molecular cell 80 (6), 955-970. e7, 2020
382020
Simultaneous binding of three recognition sites is necessary for a concerted plasmid DNA cleavage by EcoRII restriction endonuclease
G Tamulaitis, G Sasnauskas, M Mucke, V Siksnys
Journal of molecular biology 358 (2), 406-419, 2006
372006
CRISPR adaptation from a structural perspective
G Sasnauskas, V Siksnys
Current Opinion in Structural Biology 65, 17-25, 2020
352020
Tetrameric restriction enzymes: expansion to the GIY-YIG nuclease family
G Gasiunas, G Sasnauskas, G Tamulaitis, C Urbanke, D Razaniene, ...
Nucleic acids research 36 (3), 938-949, 2008
342008
DNA synapsis through transient tetramerization triggers cleavage by Ecl18kI restriction enzyme
M Zaremba, A Owsicka, G Tamulaitis, G Sasnauskas, LS Shlyakhtenko, ...
Nucleic acids research 38 (20), 7142-7154, 2010
322010
Structural basis of DNA target recognition by the B3 domain of Arabidopsis epigenome reader VAL1
G Sasnauskas, K Kauneckaitė, V Siksnys
Nucleic acids research 46 (8), 4316-4324, 2018
312018
Site-specific DNA transesterification catalyzed by a restriction enzyme
G Sasnauskas, BA Connolly, SE Halford, V Siksnys
Proceedings of the National Academy of Sciences 104 (7), 2115-2120, 2007
302007
Structural insight into the specificity of the B3 DNA-binding domains provided by the co-crystal structure of the C-terminal fragment of BfiI restriction enzyme
D Golovenko, E Manakova, L Zakrys, M Zaremba, G Sasnauskas, ...
Nucleic Acids Research 42 (6), 4113-4122, 2014
272014
Target site cleavage by the monomeric restriction enzyme BcnI requires translocation to a random DNA sequence and a switch in enzyme orientation
G Sasnauskas, G Kostiuk, G Tamulaitis, V Siksnys
Nucleic acids research 39 (20), 8844-8856, 2011
252011
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