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J. Andrew Alspaugh
J. Andrew Alspaugh
Professor of Medicine, Duke University School of Medicine
Verified email at duke.edu
Title
Cited by
Cited by
Year
Cryptococcus neoformans mating and virulence are regulated by the G-protein α subunit GPA1 and cAMP
JA Alspaugh, JR Perfect, J Heitman
Genes & development 11 (23), 3206-3217, 1997
4851997
Cyclic AMP-dependent protein kinase controls virulence of the fungal pathogen Cryptococcus neoformans
CA D'Souza, JA Alspaugh, C Yue, T Harashima, GM Cox, JR Perfect, ...
Molecular and cellular biology, 2001
3772001
The Cryptococcus neoformans capsule: a sword and a shield
TR O'Meara, JA Alspaugh
Clinical microbiology reviews 25 (3), 387-408, 2012
3602012
RAS1 regulates filamentation, mating and growth at high temperature of Cryptococcus neoformans
JA Alspaugh, LM Cavallo, JR Perfect, J Heitman
Molecular microbiology 36 (2), 352-365, 2000
2722000
Adenylyl Cyclase Functions Downstream of the Gα Protein Gpa1 and Controls Mating and Pathogenicity of Cryptococcus neoformans
JA Alspaugh, R Pukkila-Worley, T Harashima, LM Cavallo, D Funnell, ...
Eukaryotic cell 1 (1), 75-84, 2002
2402002
New horizons in antifungal therapy
KM Pianalto, JA Alspaugh
Journal of Fungi 2 (4), 26, 2016
2162016
Inhibition of Cryptococcus neoformans replication by nitrogen oxides supports the role of these molecules as effectors of macrophage-mediated cytostasis
JA Alspaugh, DL Granger
Infection and Immunity 59 (7), 2291-2296, 1991
2141991
Gene disruption by biolistic transformation in serotype D strains of Cryptococcus neoformans
RC Davidson, MC Cruz, RAL Sia, B Allen, JA Alspaugh, J Heitman
Fungal Genetics and Biology 29 (1), 38-48, 2000
2112000
Interaction of Cryptococcus neoformans Rim101 and Protein Kinase A Regulates Capsule
TR O'Meara, D Norton, MS Price, C Hay, MF Clements, CB Nichols, ...
PLoS pathogens 6 (2), e1000776, 2010
2092010
Transcriptional Network of Multiple Capsule and Melanin Genes Governed by the Cryptococcus neoformans Cyclic AMP Cascade
R Pukkila-Worley, QD Gerrald, PR Kraus, MJ Boily, MJ Davis, SS Giles, ...
Eukaryotic cell 4 (1), 190-201, 2005
1982005
Differential Effects of Inhibiting Chitin and 1,3-β-d-Glucan Synthesis in Ras and Calcineurin Mutants of Aspergillus fumigatus
JR Fortwendel, PR Juvvadi, N Pinchai, BZ Perfect, JA Alspaugh, ...
Antimicrobial agents and chemotherapy 53 (2), 476-482, 2009
1652009
The STE12α homolog is required for haploid filamentation but largely dispensable for mating and virulence in Cryptococcus neoformans
C Yue, LM Cavallo, JA Alspaugh, P Wang, GM Cox, JR Perfect, J Heitman
Genetics 153 (4), 1601-1615, 1999
1611999
Virulence mechanisms and Cryptococcus neoformans pathogenesis
JA Alspaugh
Fungal Genetics and Biology 78, 55-58, 2015
1452015
Signal Transduction Pathways Regulating Differentiation and Pathogenicity ofCryptococcus neoformans
JA Alspaugh, JR Perfect, J Heitman
Fungal Genetics and Biology 25 (1), 1-14, 1998
1361998
Cryptococcal titan cell formation is regulated by G-protein signaling in response to multiple stimuli
LH Okagaki, Y Wang, ER Ballou, TR O'Meara, YS Bahn, JA Alspaugh, ...
Eukaryotic cell 10 (10), 1306-1316, 2011
1262011
Ras1 and Ras2 contribute shared and unique roles in physiology and virulence of Cryptococcus neoformans
MS Waugh, CB Nichols, CM DeCesare, GM Cox, J Heitman, JA Alspaugh
Microbiology 148 (1), 191-201, 2002
1242002
A Ras1‐Cdc24 signal transduction pathway mediates thermotolerance in the fungal pathogen Cryptococcus neoformans
CB Nichols, ZH Perfect, JA Alspaugh
Molecular microbiology 63 (4), 1118-1130, 2007
1222007
pH response pathways in fungi: adapting to host-derived and environmental signals
K Selvig, JA Alspaugh
Mycobiology 39 (4), 249-256, 2011
1202011
The Cryptococcus neoformans Catalase Gene Family and Its Role in Antioxidant Defense
SS Giles, JE Stajich, C Nichols, QD Gerrald, JA Alspaugh, F Dietrich, ...
Eukaryotic Cell 5 (9), 1447-1459, 2006
1202006
Cryptococcus neoformans Rim101 is associated with cell wall remodeling and evasion of the host immune responses
TR O'Meara, SM Holmer, K Selvig, F Dietrich, JA Alspaugh
MBio 4 (1), 10.1128/mbio. 00522-12, 2013
1192013
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