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Laura Flight
Laura Flight
Verified email at sheffield.ac.uk
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Year
Adaptive designs in clinical trials: why use them, and how to run and report them
P Pallmann, AW Bedding, B Choodari-Oskooei, M Dimairo, L Flight, ...
BMC medicine 16 (1), 1-15, 2018
5732018
Recruitment and retention of participants in randomised controlled trials: a review of trials funded and published by the United Kingdom Health Technology Assessment Programme
SJ Walters, IB dos Anjos Henriques-Cadby, O Bortolami, L Flight, D Hind, ...
BMJ open 7 (3), e015276, 2017
3432017
Adaptive designs undertaken in clinical research: a review of registered clinical trials
I Hatfield, A Allison, L Flight, SA Julious, M Dimairo
Trials 17 (1), 1-13, 2016
1142016
Practical guide to sample size calculations: non‐inferiority and equivalence trials
L Flight, SA Julious
Pharmaceutical statistics 15 (1), 80-89, 2016
1062016
The disagreeable behaviour of the kappa statistic
L Flight, SA Julious
Pharmaceutical statistics 14 (1), 74-78, 2015
802015
Practical guide to sample size calculations: an introduction
L Flight, SA Julious
Pharmaceutical statistics 15 (1), 68-74, 2016
512016
Appropriate statistical methods for analysing partially nested randomised controlled trials with continuous outcomes: a simulation study
J Candlish, MD Teare, M Dimairo, L Flight, L Mandefield, SJ Walters
BMC medical research methodology 18 (1), 1-17, 2018
452018
Recommendations for the analysis of individually randomised controlled trials with clustering in one arm–a case of continuous outcomes
L Flight, A Allison, M Dimairo, E Lee, L Mandefield, SJ Walters
BMC Medical Research Methodology 16 (1), 1-13, 2016
412016
A review of clinical trials with an adaptive design and health economic analysis
L Flight, F Arshad, R Barnsley, K Patel, S Julious, A Brennan, S Todd
Value in Health 22 (4), 391-8, 2019
252019
Point estimation for adaptive trial designs I: A methodological review
DS Robertson, B Choodari‐Oskooei, M Dimairo, L Flight, P Pallmann, ...
Statistics in medicine 42 (2), 122-145, 2023
192023
Practical guide to sample size calculations: superiority trials
L Flight, SA Julious
Pharmaceutical statistics 15 (1), 75-79, 2016
192016
How can health economics be used in the design and analysis of adaptive clinical trials? A qualitative analysis
L Flight, S Julious, A Brennan, S Todd, D Hind
Trials 21 (1), 1-12, 2020
132020
Intravitreal ranibizumab versus aflibercept versus bevacizumab for macular oedema due to central retinal vein occlusion: the LEAVO non-inferiority three-arm RCT.
P Hykin, AT Prevost, S Sivaprasad, JC Vasconcelos, C Murphy, J Kelly, ...
Health Technology Assessment (Winchester, England) 25 (38), 1-196, 2021
122021
Comprehensive review of statistical methods for analysing patient-reported outcomes (PROs) used as primary outcomes in randomised controlled trials (RCTs) published by the UK’s …
Y Qian, SJ Walters, R Jacques, L Flight
BMJ open 11 (9), e051673, 2021
102021
Point estimation for adaptive trial designs I: a methodological review
DS Robertson, B Choodari-Oskooei, M Dimairo, L Flight, P Pallmann, ...
arXiv preprint arXiv:2105.08836, 2021
102021
Expected value of sample information to guide the design of group sequential clinical trials
L Flight, S Julious, A Brennan, S Todd
Medical Decision Making 42 (4), 461-473, 2022
92022
Mapping From Visual Acuity to EQ-5D, EQ-5D With Vision Bolt-On, and VFQ-UI in Patients With Macular Edema in the LEAVO Trial
BM Pennington, M Hernández-Alava, P Hykin, S Sivaprasad, L Flight, ...
Value in Health 23 (7), 928-935, 2020
92020
Cost Effectiveness of Ranibizumab vs Aflibercept vs Bevacizumab for the Treatment of Macular Oedema Due to Central Retinal Vein Occlusion: The LEAVO Study
B Pennington, A Alshreef, L Flight, A Metry, E Poku, P Hykin, ...
PharmacoEconomics 39 (8), 913-927, 2021
82021
Costs and staffing resource requirements for adaptive clinical trials: quantitative and qualitative results from the Costing Adaptive Trials project
N Wilson, K Biggs, S Bowden, J Brown, M Dimairo, L Flight, J Hall, ...
BMC medicine 19, 1-17, 2021
72021
The use of health economics in the design and analysis of adaptive clinical trials
L Flight
University of Sheffield, 2020
72020
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