Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9 MH Tatham, E Jaffray, OA Vaughan, JMP Desterro, CH Botting, ... Journal of Biological Chemistry 276 (38), 35368-35374, 2001 | 946 | 2001 |
Inhibition of NF-κB DNA binding by nitric oxide JR Matthews, CH Botting, M Panico, HR Morris, RT Hay Nucleic acids research 24 (12), 2236-2242, 1996 | 571 | 1996 |
The interaction of Alba, a conserved archaeal chromatin protein, with Sir2 and its regulation by acetylation SD Bell, CH Botting, BN Wardleworth, SP Jackson, MF White Science 296 (5565), 148-151, 2002 | 338 | 2002 |
Size selective protein adsorption on thiol-functionalised SBA-15 mesoporous molecular sieve HHP Yiu, CH Botting, NP Botting, PA Wright Physical Chemistry Chemical Physics 3 (15), 2983-2985, 2001 | 245 | 2001 |
Ribosomal proteins are targets for the NEDD8 pathway DP Xirodimas, A Sundqvist, A Nakamura, L Shen, C Botting, RT Hay EMBO reports 9 (3), 280-286, 2008 | 205 | 2008 |
NEDP1, a highly conserved cysteine protease that deNEDDylates Cullins HM Mendoza, L Shen, C Botting, A Lewis, J Chen, B Ink, RT Hay Journal of Biological Chemistry 278 (28), 25637-25643, 2003 | 201 | 2003 |
Miswiring the brain: Δ9‐tetrahydrocannabinol disrupts cortical development by inducing an SCG10/stathmin‐2 degradation pathway G Tortoriello, CV Morris, A Alpar, J Fuzik, SL Shirran, D Calvigioni, ... The EMBO journal 33 (7), 668-685, 2014 | 177 | 2014 |
The 3D structure of a periplasm-spanning platform required for assembly of group 1 capsular polysaccharides in Escherichia coli RF Collins, K Beis, C Dong, CH Botting, C McDonnell, RC Ford, ... Proceedings of the National Academy of Sciences 104 (7), 2390-2395, 2007 | 166 | 2007 |
Evidence of a new role for the high-osmolarity glycerol mitogen-activated protein kinase pathway in yeast: regulating adaptation to citric acid stress CL Lawrence, CH Botting, R Antrobus, PJ Coote Molecular and cellular biology 24 (8), 3307-3323, 2004 | 166 | 2004 |
Creatine kinase is physically associated with the cardiac ATP‐sensitive k+ channel in vivo RM Crawford, HJ Ranki, CH Botting, GR Budas, A Jovanovic The FASEB Journal 16 (1), 1-17, 2002 | 157 | 2002 |
Structural analysis of leader peptide binding enables leader-free cyanobactin processing J Koehnke, G Mann, AF Bent, H Ludewig, S Shirran, C Botting, T Lebl, ... Nature chemical biology 11 (8), 558-563, 2015 | 140 | 2015 |
The mechanism of patellamide macrocyclization revealed by the characterization of the PatG macrocyclase domain J Koehnke, A Bent, WE Houssen, D Zollman, F Morawitz, S Shirran, ... Nature structural & molecular biology 19 (8), 767-772, 2012 | 128 | 2012 |
The Scottish structural proteomics facility: targets, methods and outputs M Oke, LG Carter, KA Johnson, H Liu, SA McMahon, X Yan, M Kerou, ... Journal of structural and functional genomics 11 (2), 167-180, 2010 | 123 | 2010 |
Polymer precursors from catalytic reactions of natural oils MRL Furst, R Le Goff, D Quinzler, S Mecking, CH Botting, ... Green chemistry 14 (2), 472-477, 2012 | 110 | 2012 |
Citrullination of proteins: a common post-translational modification pathway induced by different nanoparticles in vitro and in vivo BM Mohamed, NK Verma, AM Davies, A McGowan, K Crosbie-Staunton, ... Nanomedicine 7 (8), 1181-1195, 2012 | 91 | 2012 |
CDK/ERK-mediated phosphorylation of the human influenza A virus NS1 protein at threonine-215 BG Hale, A Knebel, CH Botting, CS Galloway, BL Precious, D Jackson, ... Virology 383 (1), 6-11, 2009 | 90 | 2009 |
Directed evolution of a new catalytic site in 2-keto-3-deoxy-6-phosphogluconate aldolase from Escherichia coli N Wymer, LV Buchanan, D Henderson, N Mehta, CH Botting, ... Structure 9 (1), 1-9, 2001 | 90 | 2001 |
The cyanobactin heterocyclase enzyme: a processive adenylase that operates with a defined order of reaction J Koehnke, AF Bent, D Zollman, K Smith, WE Houssen, X Zhu, G Mann, ... Angewandte Chemie International Edition 52 (52), 13991-13996, 2013 | 87 | 2013 |
A metaproteomic approach gives functional insights into anaerobic digestion F Abram, AM Enright, J O’reilly, CH Botting, G Collins, V O’flaherty Journal of Applied Microbiology 110 (6), 1550-1560, 2011 | 86 | 2011 |
Novel MHC class I structures on exosomes S Lynch, SG Santos, EC Campbell, AMS Nimmo, C Botting, A Prescott, ... The Journal of Immunology 183 (3), 1884-1891, 2009 | 84 | 2009 |