Martin King
Martin King
MRC Mitochondrial Biology Unit, University of Cambridge
Verified email at - Homepage
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Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1
EL Mills, DG Ryan, HA Prag, D Dikovskaya, D Menon, Z Zaslona, ...
Nature 556 (7699), 113-117, 2018
The production of reactive oxygen species by complex I
J Hirst, MS King, KR Pryde
Biochemical Society Transactions 36 (5), 976-980, 2008
The molecular mechanism of transport by the mitochondrial ADP/ATP carrier
JJ Ruprecht, MS King, T Zögg, AA Aleksandrova, E Pardon, PG Crichton, ...
Cell 176 (3), 435-447. e15, 2019
The transport mechanism of the mitochondrial ADP/ATP carrier
ERS Kunji, A Aleksandrova, MS King, H Majd, VL Ashton, E Cerson, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (10), 2379-2393, 2016
Production of reactive oxygen species by complex I (NADH: ubiquinone oxidoreductase) from Escherichia coli and comparison to the enzyme from mitochondria
D Esterházy, MS King, G Yakovlev, J Hirst
Biochemistry 47 (12), 3964-3971, 2008
Direct assignment of EPR spectra to structurally defined iron-sulfur clusters in complex I by double electron–electron resonance
MM Roessler, MS King, AJ Robinson, FA Armstrong, J Harmer, J Hirst
Proceedings of the National Academy of Sciences 107 (5), 1930-1935, 2010
Recurrent De Novo Dominant Mutations in SLC25A4 Cause Severe Early-Onset Mitochondrial Disease and Loss of Mitochondrial DNA Copy Number
K Thompson, H Majd, C Dallabona, K Reinson, MS King, CL Alston, L He, ...
The American Journal of Human Genetics 99 (4), 860-876, 2016
Reduction of hydrophilic ubiquinones by the flavin in mitochondrial NADH: ubiquinone oxidoreductase (Complex I) and production of reactive oxygen species
MS King, MS Sharpley, J Hirst
Biochemistry 48 (9), 2053-2062, 2009
The SLC25 carrier family: important transport proteins in mitochondrial physiology and pathology
ERS Kunji, MS King, JJ Ruprecht, C Thangaratnarajah
Physiology 35 (5), 302-327, 2020
Formation of a cytoplasmic salt bridge network in the matrix state is a fundamental step in the transport mechanism of the mitochondrial ADP/ATP carrier
MS King, M Kerr, PG Crichton, R Springett, ERS Kunji
Biochimica et Biophysica Acta (BBA)-Bioenergetics 1857 (1), 14-22, 2016
Trends in thermostability provide information on the nature of substrate, inhibitor, and lipid interactions with mitochondrial carriers
PG Crichton, Y Lee, JJ Ruprecht, E Cerson, C Thangaratnarajah, MS King, ...
Journal of Biological Chemistry 290 (13), 8206-8217, 2015
The mitochondrial dicarboxylate and 2‐oxoglutarate carriers do not transport glutathione
LM Booty, MS King, C Thangaratnarajah, H Majd, AM James, ERS Kunji, ...
FEBS letters 589 (5), 621-628, 2015
Structural insight into mitochondrial β-barrel outer membrane protein biogenesis
KA Diederichs, X Ni, SE Rollauer, I Botos, X Tan, MS King, ERS Kunji, ...
Nature communications 11 (1), 3290, 2020
Structure of subcomplex Iβ of mammalian respiratory complex I leads to new supernumerary subunit assignments
J Zhu, MS King, M Yu, L Klipcan, AGW Leslie, J Hirst
Proceedings of the National Academy of Sciences 112 (39), 12087-12092, 2015
Investigating the properties of Bacillus thuringiensis Cry proteins with novel loop replacements created using combinatorial molecular biology
CR Pigott, MS King, DJ Ellar
Applied and environmental microbiology 74 (11), 3497-3511, 2008
Screening of candidate substrates and coupling ions of transporters by thermostability shift assays
H Majd, MS King, SM Palmer, AC Smith, LDH Elbourne, IT Paulsen, ...
eLife 7, e38821, 2018
How detergent impacts membrane proteins: atomic-level views of mitochondrial carriers in dodecylphosphocholine
V Kurauskas, A Hessel, P Ma, P Lunetti, K Weinhäupl, L Imbert, ...
The journal of physical chemistry letters 9 (5), 933-938, 2018
Mitochondrial oxodicarboxylate carrier deficiency is associated with mitochondrial DNA depletion and spinal muscular atrophy–like disease
V Boczonadi, MS King, AC Smith, M Olahova, B Bansagi, A Roos, ...
Genetics in Medicine 20 (10), 1224-1235, 2018
Pathogenic mutations of the human mitochondrial citrate carrier SLC25A1 lead to impaired citrate export required for lipid, dolichol, ubiquinone and sterol synthesis
H Majd, MS King, AC Smith, ERS Kunji
Biochimica et Biophysica Acta (BBA)-Bioenergetics 1859 (1), 1-7, 2018
Calcium regulation of the human mitochondrial ATP-Mg/Pi carrier SLC25A24 uses a locking pin mechanism
SPD Harborne, MS King, PG Crichton, ERS Kunji
Scientific Reports 7 (1), 45383, 2017
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