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Le Yuan
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Deep learning based kcat prediction enables improved enzyme constrained model reconstruction
F Li, L Yuan, H Lu, G Li, Y Chen, MKM Engqvist, EJ Kerkhoven, J Nielsen
Nature Catalysis 5, 662–672, 2022
1372022
novoPathFinder: a webserver of designing novel-pathway with integrating GEM-model
S Ding, Y Tian, P Cai, D Zhang, X Cheng, D Sun, L Yuan, J Chen, W Tu, ...
Nucleic acids research 48 (W1), W477-W487, 2020
332020
AdditiveChem: a comprehensive bioinformatics knowledge-base for food additive chemicals
D Zhang, X Cheng, D Sun, S Ding, P Cai, L Yuan, Y Tian, W Tu, QN Hu
Food chemistry 308, 125519, 2020
322020
Improving recombinant protein production by yeast through genome-scale modeling using proteome constraints
F Li, Y Chen, Q Qi, Y Wang, L Yuan, M Huang, IE Elsemman, A Feizi, ...
Nature communications 13 (1), 2969, 2022
232022
FRCD: A comprehensive food risk component database with molecular scaffold, chemical diversity, toxicity, and biodegradability analysis
D Zhang, L Gong, S Ding, Y Tian, C Jia, D Liu, M Han, X Cheng, D Sun, ...
Food chemistry 318, 126470, 2020
232020
PrecursorFinder: a customized biosynthetic precursor explorer
L Yuan, Y Tian, S Ding, Y Liu, F Chen, T Zhang, W Tu, J Chen, QN Hu
Bioinformatics 35 (9), 1603-1604, 2019
192019
Yeast metabolic innovations emerged via expanded metabolic network and gene positive selection
H Lu, F Li, L Yuan, I Domenzain, R Yu, H Wang, G Li, Y Chen, B Ji, ...
Molecular Systems Biology 17 (10), e10427, 2021
182021
Bio2Rxn: sequence-based enzymatic reaction predictions by a consensus strategy
T Zhang, Y Tian, L Yuan, F Chen, A Ren, QN Hu
Bioinformatics 36 (11), 3600-3601, 2020
182020
Data-driven rational biosynthesis design: from molecules to cell factories
F Chen, L Yuan, S Ding, Y Tian, QN Hu
Briefings in Bioinformatics 21 (4), 1238-1248, 2020
122020
BCSExplorer: a customized biosynthetic chemical space explorer with multifunctional objective function analysis
Y Tian, L Wu, L Yuan, S Ding, F Chen, T Zhang, A Ren, D Zhang, W Tu, ...
Bioinformatics 36 (5), 1642-1643, 2020
122020
CF-targeter: a rational biological cell factory targeting platform for biosynthetic target chemicals
S Ding, P Cai, L Yuan, Y Tian, W Tu, D Zhang, X Cheng, D Sun, J Chen, ...
ACS Synthetic Biology 8 (10), 2280-2286, 2019
62019
HGTphyloDetect: facilitating the identification and phylogenetic analysis of horizontal gene transfer
L Yuan, H Lu, F Li, J Nielsen, EJ Kerkhoven
Briefings in Bioinformatics 24 (2), bbad035, 2023
52023
Reconstruction, simulation and analysis of enzyme-constrained metabolic models using GECKO Toolbox 3.0
Y Chen, J Gustafsson, A Tafur Rangel, M Anton, I Domenzain, ...
Nature Protocols, 1-39, 2024
42024
ChemHub: a knowledgebase of functional chemicals for synthetic biology studies
M Han, D Zhang, S Ding, Y Tian, X Cheng, L Yuan, D Sun, D Liu, L Gong, ...
Bioinformatics 37 (22), 4275-4276, 2021
32021
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