| Phase-plate cryo-EM structure of a class B GPCR–G-protein complex YL Liang, M Khoshouei, M Radjainia, Y Zhang, A Glukhova, J Tarrasch, ... Nature 546 (7656), 118-123, 2017 | 481 | 2017 |
| The Concise Guide to PHARMACOLOGY 2021/22: G protein‐coupled receptors SPH Alexander, A Christopoulos, AP Davenport, E Kelly, A Mathie, ... British journal of pharmacology 178, S27-S156, 2021 | 445 | 2021 |
| Crystal structures of the M1 and M4 muscarinic acetylcholine receptors DM Thal, B Sun, D Feng, V Nawaratne, K Leach, CC Felder, MG Bures, ... Nature 531 (7594), 335-340, 2016 | 335 | 2016 |
| Structure of the adenosine-bound human adenosine A1 receptor–Gi complex CJ Draper-Joyce, M Khoshouei, DM Thal, YL Liang, ATN Nguyen, ... Nature 558 (7711), 559-563, 2018 | 320 | 2018 |
| Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor–Gs complex YL Liang, M Khoshouei, A Glukhova, SGB Furness, P Zhao, L Clydesdale, ... Nature 555 (7694), 121-125, 2018 | 298 | 2018 |
| Structure of the adenosine A1 receptor reveals the basis for subtype selectivity A Glukhova, DM Thal, AT Nguyen, EA Vecchio, M Jörg, PJ Scammells, ... Cell 168 (5), 867-877. e13, 2017 | 274 | 2017 |
| Structural insights into G-protein-coupled receptor allostery DM Thal, A Glukhova, PM Sexton, A Christopoulos Nature 559 (7712), 45-53, 2018 | 271 | 2018 |
| Paroxetine is a direct inhibitor of g protein-coupled receptor kinase 2 and increases myocardial contractility DM Thal, KT Homan, J Chen, EK Wu, PM Hinkle, ZM Huang, JK Chuprun, ... ACS chemical biology 7 (11), 1830-1839, 2012 | 215 | 2012 |
| Molecular mechanism of selectivity among G protein-coupled receptor kinase 2 inhibitors DM Thal, RY Yeow, C Schoenau, J Huber, JJG Tesmer Molecular pharmacology 80 (2), 294-303, 2011 | 137 | 2011 |
| Incorporation and replication of 8-oxo-deoxyguanosine by the human mitochondrial DNA polymerase JW Hanes, DM Thal, KA Johnson Journal of biological chemistry 281 (47), 36241-36248, 2006 | 105 | 2006 |
| Positive allosteric mechanisms of adenosine A1 receptor-mediated analgesia CJ Draper-Joyce, R Bhola, J Wang, A Bhattarai, ATN Nguyen, ... Nature 597 (7877), 571-576, 2021 | 92 | 2021 |
| An autoinhibitory helix in the C-terminal region of phospholipase C-β mediates Gαq activation AM Lyon, VM Tesmer, VD Dhamsania, DM Thal, J Gutierrez, ... Nature structural & molecular biology 18 (9), 999-1005, 2011 | 89 | 2011 |
| Molecular determinants of allosteric modulation at the M1 muscarinic acetylcholine receptor A Abdul-Ridha, L Lopez, P Keov, DM Thal, SN Mistry, PM Sexton, ... Journal of Biological Chemistry 289 (9), 6067-6079, 2014 | 73 | 2014 |
| Crystal structure of the M5 muscarinic acetylcholine receptor Z Vuckovic, PR Gentry, AE Berizzi, K Hirata, S Varghese, G Thompson, ... Proceedings of the National Academy of Sciences 116 (51), 26001-26007, 2019 | 70 | 2019 |
| Recent advances in the determination of G protein-coupled receptor structures DM Thal, Z Vuckovic, CJ Draper-Joyce, YL Liang, A Glukhova, ... Current opinion in structural biology 51, 28-34, 2018 | 63 | 2018 |
| Assembly of high order Gαq-effector complexes with RGS proteins A Shankaranarayanan, DM Thal, VM Tesmer, DL Roman, RR Neubig, ... Journal of biological chemistry 283 (50), 34923-34934, 2008 | 55 | 2008 |
| Selective G protein signaling driven by substance P–neurokinin receptor dynamics JA Harris, B Faust, AB Gondin, MA Dämgen, CM Suomivuori, NA Veldhuis, ... Nature chemical biology 18 (1), 109-115, 2022 | 49 | 2022 |
| Structures of the human cholecystokinin 1 (CCK1) receptor bound to Gs and Gq mimetic proteins provide insight into mechanisms of G protein selectivity JI Mobbs, MJ Belousoff, KG Harikumar, SJ Piper, X Xu, SGB Furness, ... PLoS biology 19 (6), e3001295, 2021 | 49 | 2021 |
| Toward an understanding of the structural basis of allostery in muscarinic acetylcholine receptors WAC Burger, PM Sexton, A Christopoulos, DM Thal Journal of General Physiology 150 (10), 1360-1372, 2018 | 48 | 2018 |
| Unique hydrophobic extension of the RGS2 amphipathic helix domain imparts increased plasma membrane binding and function relative to other RGS R4/B subfamily members S Gu, J He, WT Ho, S Ramineni, DM Thal, R Natesh, JJG Tesmer, ... Journal of biological chemistry 282 (45), 33064-33075, 2007 | 41 | 2007 |
