| Expression of interleukin (IL)-18 and functional IL-18 receptor on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for atherogenesis N Gerdes, GK Sukhova, P Libby, RS Reynolds, JL Young, U Schönbeck The Journal of experimental medicine 195 (2), 245-257, 2002 | 706 | 2002 |
| Metformin inhibits proinflammatory responses and nuclear factor-κB in human vascular wall cells K Isoda, JL Young, A Zirlik, LA MacFarlane, N Tsuboi, N Gerdes, ... Arteriosclerosis, thrombosis, and vascular biology 26 (3), 611-617, 2006 | 669 | 2006 |
| Expression of neutrophil collagenase (matrix metalloproteinase-8) in human atheroma: a novel collagenolytic pathway suggested by transcriptional profiling MP Herman, GK Sukhova, P Libby, N Gerdes, N Tang, DB Horton, ... Circulation 104 (16), 1899-1904, 2001 | 495 | 2001 |
| Depletion of FOXP3+ regulatory T cells promotes hypercholesterolemia and atherosclerosis R Klingenberg, N Gerdes, RM Badeau, A Gisterå, D Strodthoff, ... The Journal of clinical investigation 123 (3), 1323-1334, 2013 | 408 | 2013 |
| Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis D Lievens, A Zernecke, T Seijkens, O Soehnlein, L Beckers, ICA Munnix, ... Blood, The Journal of the American Society of Hematology 116 (20), 4317-4327, 2010 | 357 | 2010 |
| Thymic B cells are licensed to present self antigens for central T cell tolerance induction T Yamano, J Nedjic, M Hinterberger, M Steinert, S Koser, S Pinto, ... Immunity 42 (6), 1048-1061, 2015 | 291 | 2015 |
| CD40 ligand mediates inflammation independently of CD40 by interaction with Mac-1 A Zirlik, C Maier, N Gerdes, L MacFarlane, J Soosairajah, U Bavendiek, ... Circulation 115 (12), 1571-1580, 2007 | 281 | 2007 |
| Oxidized low-density lipoprotein augments and 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors limit CD40 and CD40L expression in human vascular cells U Schönbeck, N Gerdes, N Varo, RS Reynolds, DB Horton, ... Circulation 106 (23), 2888-2893, 2002 | 253 | 2002 |
| Intranasal immunization with an apolipoprotein B-100 fusion protein induces antigen-specific regulatory T cells and reduces atherosclerosis R Klingenberg, M Lebens, A Hermansson, GN Fredrikson, D Strodthoff, ... Arteriosclerosis, thrombosis, and vascular biology 30 (5), 946-952, 2010 | 234 | 2010 |
| T(H)2 Predominant Immune Responses Prevail in Human Abdominal Aortic Aneurysm U Schönbeck, GK Sukhova, N Gerdes, P Libby The American journal of pathology 161 (2), 499-506, 2002 | 219 | 2002 |
| Interleukin-18, the metabolic syndrome, and subclinical atherosclerosis: results from the Dallas Heart Study A Zirlik, SM Abdullah, N Gerdes, L MacFarlane, U Schönbeck, A Khera, ... Arteriosclerosis, thrombosis, and vascular biology 27 (9), 2043-2049, 2007 | 167 | 2007 |
| Targeting CD40-induced TRAF6 signaling in macrophages reduces atherosclerosis TTP Seijkens, CM van Tiel, PJH Kusters, D Atzler, O Soehnlein, ... Journal of the American College of Cardiology 71 (5), 527-542, 2018 | 156 | 2018 |
| Matrix metalloproteinase-14 deficiency in bone marrow–derived cells promotes collagen accumulation in mouse atherosclerotic plaques F Schneider, GK Sukhova, M Aikawa, J Canner, N Gerdes, SMT Tang, ... Circulation 117 (7), 931-939, 2008 | 152 | 2008 |
| Platelets regulate CD4+ T-cell differentiation via multiple chemokines in humans N Gerdes, L Zhu, M Ersoy, A Hermansson, P Hjemdahl, H Hu, ... Thrombosis and haemostasis 106 (08), 353-362, 2011 | 142 | 2011 |
| Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance A Chatzigeorgiou, T Seijkens, B Zarzycka, D Engel, M Poggi, ... Proceedings of the National Academy of Sciences 111 (7), 2686-2691, 2014 | 140 | 2014 |
| Artery tertiary lymphoid organs contribute to innate and adaptive immune responses in advanced mouse atherosclerosis SK Mohanta, C Yin, L Peng, P Srikakulapu, V Bontha, D Hu, F Weih, ... Circulation research 114 (11), 1772-1787, 2014 | 139 | 2014 |
| TRAF-1,-2,-3,-5, and-6 are induced in atherosclerotic plaques and differentially mediate proinflammatory functions of CD40L in endothelial cells A Zirlik, U Bavendiek, P Libby, L MacFarlane, N Gerdes, J Jagielska, ... Arteriosclerosis, thrombosis, and vascular biology 27 (5), 1101-1107, 2007 | 130 | 2007 |
| Toll-like receptor 3 and 4 signalling through the TRIF and TRAM adaptors in haematopoietic cells promotes atherosclerosis AM Lundberg, DFJ Ketelhuth, ME Johansson, N Gerdes, S Liu, ... Cardiovascular research 99 (2), 364-373, 2013 | 123 | 2013 |
| Platelet CD40 exacerbates atherosclerosis by transcellular activation of endothelial cells and leukocytes N Gerdes, T Seijkens, D Lievens, MJE Kuijpers, H Winkels, D Projahn, ... Arteriosclerosis, thrombosis, and vascular biology 36 (3), 482-490, 2016 | 122 | 2016 |
| Regulatory T cells in atherosclerosis: critical immune regulatory function and therapeutic potential C Spitz, H Winkels, C Bürger, C Weber, E Lutgens, GK Hansson, ... Cellular and molecular life sciences 73, 901-922, 2016 | 118 | 2016 |
Esther LutgensMayo Clinic, Rochester, MN, USAVerified email at mayo.edu
