Anthony Maxwell

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Andrew D BatesUniversity of LiverpoolVerified email at liv.ac.uk
Clare StevensonJohn Innes CentreVerified email at jic.ac.uk
Dale WigleyVerified email at imperial.ac.uk
Sotirios C. KampranisProfessor of Biochemical Engineering, University of CopenhagenVerified email at plen.ku.dk
Chris WillmottSenior Lecturer, Biochemistry, University of LeicesterVerified email at leicester.ac.uk
Natassja BushJohn Innes CentreVerified email at jic.ac.uk
Keith RobertsJohn Innes Centre (retired)Verified email at keith-roberts.org.uk
Mark J. ButtnerHead, Dept. of Molecular Microbiology, John Innes CentreVerified email at jic.ac.uk
Sarah HarrisLecturer in Biological Physics, University of LeedsVerified email at leeds.ac.uk
Manlio PalumboUniversity of PadovaVerified email at unipd.it
Eleanor DodsonProfessorVerified email at york.ac.uk
Professor Gideon Davies, FRS, FMedSciYSBL, Department of Chemistry, University of YorkVerified email at york.ac.uk
Valakunja NagarajaProfessor of Microbiology, Indian Institute of ScienceVerified email at iisc.ac.in
Tung BK LeGroup Leader-Associate Professor, John Innes Centre, UKVerified email at jic.ac.uk
Joao Morais CabralIBMC/i3SVerified email at ibmc.up.pt
Richard J Lewisex-Newcastle University; now at RSPB and Cambridge UniversityVerified email at rspb.org.uk
Matthew Warren VettingAlbert Einstein College of MedicineVerified email at einstein.yu.edu
Benjamin BaxResearch FellowVerified email at cardiff.ac.uk
Florian HollfelderUniversity of CambridgeVerified email at cam.ac.uk
Deborah ZambleUniversity of TorontoVerified email at chem.utoronto.ca

Anthony Maxwell

Project Leader, John Innes Centre

Verified email at jic.ac.uk - Homepage

DNA topoisomerases antibiotics DNA topology


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DNA gyrase: structure and function RJ Reece, A Maxwell Critical reviews in biochemistry and molecular biology 26 (3-4), 335-375, 1991	872	1991
Crystal structure of an N-terminal fragment of the DNA gyrase B protein DB Wigley, GJ Davies, EJ Dodson, A Maxwell, G Dodson Nature 351 (6328), 624-629, 1991	668	1991
Exploiting bacterial DNA gyrase as a drug target: current state and perspectives F Collin, S Karkare, A Maxwell Applied microbiology and biotechnology 92, 479-497, 2011	595	2011
Crystal structure of the breakage–reunion domain of DNA gyrase JHM Cabral, AP Jackson, CV Smith, N Shikotra, A Maxwell, ... Nature 388 (6645), 903-906, 1997	592	1997
DNA topology AD Bates, A Maxwell Oxford University Press, USA, 2005	571	2005
DNA gyrase as a drug target A Maxwell Trends in microbiology 5 (3), 102-109, 1997	453	1997
The 43-kilodalton N-terminal fragment of the DNA gyrase B protein hydrolyzes ATP and binds coumarin drugs JA Ali, AP Jackson, AJ Howells, A Maxwell Biochemistry 32 (10), 2717-2724, 1993	423	1993
The nature of inhibition of DNA gyrase by the coumarins and the cyclothialidines revealed by X‐ray crystallography. RJ Lewis, OM Singh, CV Smith, T Skarzynski, A Maxwell, AJ Wonacott, ... The EMBO journal 15 (6), 1412-1420, 1996	398	1996
A fluoroquinolone resistance protein from Mycobacterium tuberculosis that mimics DNA SS Hegde, MW Vetting, SL Roderick, LA Mitchenall, A Maxwell, HE Takiff, ... Science 308 (5727), 1480-1483, 2005	364	2005
A single point mutation in the DNA gyrase A protein greatly reduces binding of fluoroquinolones to the gyrase-DNA complex CJ Willmott, A Maxwell Antimicrobial agents and chemotherapy 37 (1), 126-127, 1993	360	1993
Mechanistic aspects of DNA topoisomerases A Maxwell, M Gellert Advances in protein chemistry 38, 69-107, 1986	343	1986
The interaction between coumarin drugs and DNA gyrase A Maxwell Molecular microbiology 9 (4), 681-686, 1993	335	1993
The ATP-binding site of type II topoisomerases as a target for antibacterial drugs A Maxwell, DM Lawson Current topics in medicinal chemistry 3 (3), 283-303, 2003	311	2003
Novobiocin: redesigning a DNA gyrase inhibitor for selective inhibition of hsp90 JA Burlison, L Neckers, AB Smith, A Maxwell, BSJ Blagg Journal of the American Chemical Society 128 (48), 15529-15536, 2006	281	2006
Arabidopsis SPO11‐2 functions with SPO11‐1 in meiotic recombination NJ Stacey, T Kuromori, Y Azumi, G Roberts, C Breuer, T Wada, A Maxwell, ... The Plant Journal 48 (2), 206-216, 2006	264	2006
Interaction between DNA Gyrase and Quinolones: Effects of Alanine Mutations at GyrA Subunit Residues Ser⁸³and Asp⁸⁷ FM Barnard, A Maxwell Antimicrobial agents and chemotherapy 45 (7), 1994-2000, 2001	252	2001
DNA topology AD Bates, A Maxwell IRL Press at Oxford University Press, 1993	231	1993
Quinolones: mechanism, lethality and their contributions to antibiotic resistance NG Bush, I Diez-Santos, LR Abbott, A Maxwell Molecules 25 (23), 5662, 2020	228	2020
The molecular basis of quinolone action A MAXWELL Journal of Antimicrobial Chemotherapy 30 (4), 409-414, 1992	221	1992
The interaction of coumarin antibiotics with fragments of the DNA gyrase B protein NA Gormley, G Orphanides, A Meyer, PM Cullis, A Maxwell Biochemistry 35 (15), 5083-5092, 1996	219	1996

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