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Andreas Villunger
Andreas Villunger
Professor, Developmental Immunology, Biocenter, Innsbruck Medical University, Austria
Verified email at i-med.ac.at - Homepage
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Year
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ...
Cell Death & Differentiation 25 (3), 486-541, 2018
52332018
p53-and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa
A Villunger, EM Michalak, L Coultas, F Mullauer, G Böck, ...
Science 302 (5647), 1036-1038, 2003
16072003
LDHA-associated lactic acid production blunts tumor immunosurveillance by T and NK cells
A Brand, K Singer, GE Koehl, M Kolitzus, G Schoenhammer, A Thiel, ...
Cell metabolism 24 (5), 657-671, 2016
13062016
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015
L Galluzzi, BS Pedro, I Vitale, SA Aaronson, JM Abrams, D Adam, ...
Cell Death & Differentiation 22 (1), 58-73, 2015
11372015
Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis
H Puthalakath, A Villunger, LA O'Reilly, JG Beaumont, L Coultas, ...
Science 293 (5536), 1829-1832, 2001
8312001
FOXO3a-dependent regulation of Puma in response to cytokine/growth factor withdrawal
H You, M Pellegrini, K Tsuchihara, K Yamamoto, G Hacker, M Erlacher, ...
The Journal of experimental medicine 203 (7), 1657-1663, 2006
4962006
Bcl2 family proteins in carcinogenesis and the treatment of cancer
A Frenzel, F Grespi, W Chmelewskij, A Villunger
Apoptosis 14, 584-596, 2009
4422009
Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic
J Kuroda, H Puthalakath, MS Cragg, PN Kelly, P Bouillet, DCS Huang, ...
Proceedings of the National Academy of Sciences 103 (40), 14907-14912, 2006
3762006
Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-xL
DCS Huang, M Hahne, M Schroeter, K Frei, A Fontana, A Villunger, ...
Proceedings of the National Academy of Sciences 96 (26), 14871-14876, 1999
3761999
Signalling strength determines proapoptotic functions of STING
MF Gulen, U Koch, SM Haag, F Schuler, L Apetoh, A Villunger, F Radtke, ...
Nature communications 8 (1), 427, 2017
3622017
BH3-only proteins Puma and Bim are rate-limiting for γ-radiation–and glucocorticoid-induced apoptosis of lymphoid cells in vivo
M Erlacher, EM Michalak, PN Kelly, V Labi, H Niederegger, L Coultas, ...
Blood 106 (13), 4131-4138, 2005
3432005
Key roles of BIM-driven apoptosis in epithelial tumors and rational chemotherapy
TT Tan, K Degenhardt, DA Nelson, B Beaudoin, W Nieves-Neira, ...
Cancer cell 7 (3), 227-238, 2005
3392005
Noxa: at the tip of the balance between life and death
C Ploner, R Kofler, A Villunger
Oncogene 27 (1), S84-S92, 2008
3262008
Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci
E Melum, A Franke, C Schramm, TJ Weismüller, DN Gotthardt, FA Offner, ...
Nature genetics 43 (1), 17-19, 2011
2852011
Puma cooperates with Bim, the rate-limiting BH3-only protein in cell death during lymphocyte development, in apoptosis induction
M Erlacher, V Labi, C Manzl, G Böck, A Tzankov, G Häcker, E Michalak, ...
The Journal of experimental medicine 203 (13), 2939-2951, 2006
2602006
p14–MP1-MEK1 signaling regulates endosomal traffic and cellular proliferation during tissue homeostasis
D Teis, N Taub, R Kurzbauer, D Hilber, ME de Araujo, M Erlacher, ...
The Journal of cell biology 175 (6), 861-868, 2006
2542006
In several cell types tumour suppressor p53 induces apoptosis largely via Puma but Noxa can contribute
EM Michalak, A Villunger, JM Adams, A Strasser
Cell Death & Differentiation 15 (6), 1019-1029, 2008
2422008
How important are post-translational modifications in p53 for selectivity in target-gene transcription and tumour suppression?
A Olsson, C Manzl, A Strasser, A Villunger
Cell Death & Differentiation 14 (9), 1561-1575, 2007
2342007
Drug-induced apoptosis is associated with enhanced Fas (Apo-1/CD95) ligand expression but occurs independently of Fas (Apo-1/CD95) signaling in human T-acute lymphatic leukemia …
A Villunger, A Egle, M Kos, BL Hartmann, S Geley, R Kofler, R Greil
Cancer research 57 (16), 3331-3334, 1997
2081997
Targeting the Bcl-2-regulated apoptosis pathway by BH3 mimetics: a breakthrough in anticancer therapy?
V Labi, F Grespi, F Baumgartner, A Villunger
Cell Death & Differentiation 15 (6), 977-987, 2008
2032008
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