Frank von Delft
Frank von Delft
Principal Investigator: Protein Crystallography, SGC, Oxford University
Verified email at sgc.ox.ac.uk
TitleCited byYear
Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin
L Pellegrini, DF Burke, F von Delft, B Mulloy, TL Blundell
Nature 407 (6807), 1029, 2000
7932000
Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity
SS Ng, KL Kavanagh, MA McDonough, D Butler, ES Pilka, BMR Lienard, ...
Nature 448 (7149), 87, 2007
2862007
Structures of ABCB10, a human ATP-binding cassette transporter in apo-and nucleotide-bound states
CA Shintre, ACW Pike, Q Li, JI Kim, AJ Barr, S Goubin, L Shrestha, J Yang, ...
Proceedings of the National Academy of Sciences 110 (24), 9710-9715, 2013
1952013
Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming
G Kochan, T Krojer, D Harvey, R Fischer, L Chen, M Vollmar, F von Delft, ...
Proceedings of the National Academy of Sciences 108 (19), 7745-7750, 2011
1902011
Structure of the CaMKIIδ/calmodulin complex reveals the molecular mechanism of CaMKII kinase activation
P Rellos, ACW Pike, FH Niesen, E Salah, WH Lee, F Von Delft, S Knapp
PLoS biology 8 (7), e1000426, 2010
1742010
Structural basis for Cul3 protein assembly with the BTB-Kelch family of E3 ubiquitin ligases
P Canning, CDO Cooper, T Krojer, JW Murray, ACW Pike, A Chaikuad, ...
Journal of Biological Chemistry 288 (11), 7803-7814, 2013
1432013
Structure of the bone morphogenetic protein receptor ALK2 and implications for fibrodysplasia ossificans progressiva
A Chaikuad, I Alfano, G Kerr, CE Sanvitale, JH Boergermann, JT Triffitt, ...
Journal of Biological Chemistry 287 (44), 36990-36998, 2012
1212012
Identification of macrodomain proteins as novel O-acetyl-ADP-ribose deacetylases
D Chen, M Vollmar, MN Rossi, C Phillips, R Kraehenbuehl, D Slade, ...
Journal of Biological Chemistry 286 (15), 13261-13271, 2011
1202011
Crystal structure of aspartate decarboxylase at 2.2 Ċ resolution provides evidence for an ester in protein self–processing
A Albert, V Dhanaraj, U Genschel, G Khan, MK Ramjee, R Pulido, ...
Nature structural biology 5 (4), 289, 1998
1091998
The crystal structure of human GLRX5: iron–sulfur cluster co-ordination, tetrameric assembly and monomer activity
C Johansson, AK Roos, SJ Montano, R Sengupta, P Filippakopoulos, ...
Biochemical Journal 433 (2), 303-311, 2010
992010
Structural snapshots for the conformation-dependent catalysis by human medium-chain acyl-coenzyme A synthetase ACSM2A
G Kochan, ES Pilka, F von Delft, U Oppermann, WW Yue
Journal of molecular biology 388 (5), 997-1008, 2009
982009
Crystal structures of the catalytic domain of human soluble guanylate cyclase
CK Allerston, F von Delft, O Gileadi
PloS one 8 (3), e57644, 2013
972013
Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylases
NR Rose, ECY Woon, A Tumber, LJ Walport, R Chowdhury, XS Li, ...
Journal of medicinal chemistry 55 (14), 6639-6643, 2012
942012
Ribosomal oxygenases are structurally conserved from prokaryotes to humans
R Chowdhury, NC Brissett, T Krojer, C Ho, SS Ng, IJ Clifton, W Ge, ...
Nature 510 (7505), 422, 2014
792014
The crystal structure of E. coli pantothenate synthetase confirms it as a member of the cytidylyltransferase superfamily
F von Delft, A Lewendon, V Dhanaraj, TL Blundell, C Abell, AG Smith
Structure 9 (5), 439-450, 2001
792001
The structural basis of ZMPSTE24-dependent laminopathies
A Quigley, YY Dong, ACW Pike, L Dong, L Shrestha, G Berridge, ...
Science 339 (6127), 1604-1607, 2013
742013
Crystal structure of the PIM2 kinase in complex with an organoruthenium inhibitor
AN Bullock, S Russo, A Amos, N Pagano, H Bregman, JE Debreczeni, ...
PLoS One 4 (10), e7112, 2009
732009
Targeting low-druggability bromodomains: fragment based screening and inhibitor design against the BAZ2B bromodomain
FM Ferguson, O Fedorov, A Chaikuad, M Philpott, JRC Muniz, I Felletar, ...
Journal of medicinal chemistry 56 (24), 10183-10187, 2013
722013
Structural and mechanistic studies on γ-butyrobetaine hydroxylase
IKH Leung, TJ Krojer, GT Kochan, L Henry, F von Delft, TDW Claridge, ...
Chemistry & biology 17 (12), 1316-1324, 2010
682010
The scientific impact of the Structural Genomics Consortium: a protein family and ligand-centered approach to medically-relevant human proteins
O Gileadi, S Knapp, WH Lee, BD Marsden, S Müller, FH Niesen, ...
Journal of structural and functional genomics 8 (2-3), 107-119, 2007
672007
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