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Justin Eagles
Justin Eagles
Verified email at ucdenver.edu
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Year
A patient tumor transplant model of squamous cell cancer identifies PI3K inhibitors as candidate therapeutics in defined molecular bins
SB Keysar, DP Astling, RT Anderson, BW Vogler, DW Bowles, JJ Morton, ...
Molecular oncology 7 (4), 776-790, 2013
1712013
XactMice: humanizing mouse bone marrow enables microenvironment reconstitution in a patient-derived xenograft model of head and neck cancer
JJ Morton, G Bird, SB Keysar, DP Astling, TR Lyons, RT Anderson, ...
Oncogene 35 (3), 290-300, 2016
1342016
Regulation of head and neck squamous cancer stem cells by PI3K and SOX2
SB Keysar, PN Le, B Miller, BC Jackson, JR Eagles, C Nieto, J Kim, ...
Journal of the National Cancer Institute 109 (1), djw189, 2017
1212017
Hedgehog signaling alters reliance on EGF receptor signaling and mediates anti-EGFR therapeutic resistance in head and neck cancer
SB Keysar, PN Le, RT Anderson, JJ Morton, DW Bowles, JJ Paylor, ...
Cancer research 73 (11), 3381-3392, 2013
1042013
FGFR1 expression levels predict BGJ398 sensitivity of FGFR1-dependent head and neck squamous cell cancers
F Göke, A Franzen, TK Hinz, LA Marek, P Yoon, R Sharma, M Bode, ...
Clinical cancer research 21 (19), 4356-4364, 2015
982015
Hedgehog signaling drives radioresistance and stroma-driven tumor repopulation in head and neck squamous cancers
GN Gan, J Eagles, SB Keysar, G Wang, MJ Glogowska, C Altunbas, ...
Cancer research 74 (23), 7024-7036, 2014
732014
Wnt signaling dynamics in head and neck squamous cell cancer tumor‐stroma interactions
PN Le, SB Keysar, B Miller, JR Eagles, TS Chimed, J Reisinger, ...
Molecular carcinogenesis 58 (3), 398-410, 2019
562019
A pilot study of cetuximab and the hedgehog inhibitor IPI-926 in recurrent/metastatic head and neck squamous cell carcinoma
DW Bowles, SB Keysar, JR Eagles, G Wang, MJ Glogowska, ...
Oral oncology 53, 74-79, 2016
402016
The dual pathway inhibitor rigosertib is effective in direct patient tumor xenografts of head and neck squamous cell carcinomas
RT Anderson, SB Keysar, DW Bowles, MJ Glogowska, DP Astling, ...
Molecular cancer therapeutics 12 (10), 1994-2005, 2013
362013
Salivary gland cancer patient-derived xenografts enable characterization of cancer stem cells and new gene events associated with tumor progression
SB Keysar, JR Eagles, B Miller, BC Jackson, FN Chowdhury, J Reisinger, ...
Clinical Cancer Research 24 (12), 2935-2943, 2018
302018
Patterns of facial trauma before and after legalization of marijuana in Denver, Colorado: a joint study between two Denver hospitals
M Sokoya, J Eagles, T Okland, D Coughlin, H Dauber, C Greenlee, ...
The American Journal of Emergency Medicine 36 (5), 780-783, 2018
212018
An inducible TGF-β2-TGFβR pathway modulates the sensitivity of HNSCC cells to tyrosine kinase inhibitors targeting dominant receptor tyrosine kinases
EK Kleczko, J Kim, SB Keysar, LR Heasley, JR Eagles, M Simon, ...
PLoS One 10 (5), e0123600, 2015
122015
Cobimetinib: inhibiting MEK1/2 in BRAF V600-mutant melanoma.
JR Eagles, A Jimeno
Drugs of Today (Barcelona, Spain: 1998) 52 (11), 593-605, 2016
82016
Radiation dose uncertainty and correction for a mouse orthotopic and xenograft irradiation model
GN Gan, C Altunbas, JJ Morton, J Eagles, J Backus, W Dzingle, D Raben, ...
International journal of radiation biology 92 (1), 50-56, 2016
32016
Survival Impact of Local Therapy for Thyroid Carcinoma: A Surveillance, Epidemiology, and End Results Analysis
W Sumner, A Amini, J McDermott, J Eagles, A Jimeno, DW Bowles, ...
International Journal of Radiation Oncology, Biology, Physics 94 (4), 951, 2016
2016
XactMice
JJ Morton, G Bird, SB Keysar, DP Astling, TR Lyons, RT Anderson, ...
Oncogene, 2015
2015
Radiation Dose Uncertainty in a Mouse Head and Neck Irradiation Model
GN Gan, J Eagles-Soukup, D Raben, A Jimeno, C Altunbus
International Journal of Radiation Oncology, Biology, Physics 90 (1), S790, 2014
2014
Hedgehog Pathway Mediates Head/Neck Radiation Resistance and Tumor Repopulation: Molecular Biology and Therapeutics
G Gan, S Keysar, J Eagles-Soukup, R Anderson, J Morton, P Le, ...
International Journal of Radiation Oncology, Biology, Physics 88 (2), 469, 2014
2014
The Hedgehog Pathway Modulates Radiation Therapy Resistance in Head-and-Neck Cancer
GN Gan, S Keysar, J Eagles-Soukup, R Anderson, C Altunbus, J Morton, ...
International Journal of Radiation Oncology, Biology, Physics 87 (2), S140-S141, 2013
2013
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