A patient tumor transplant model of squamous cell cancer identifies PI3K inhibitors as candidate therapeutics in defined molecular bins SB Keysar, DP Astling, RT Anderson, BW Vogler, DW Bowles, JJ Morton, ... Molecular oncology 7 (4), 776-790, 2013 | 171 | 2013 |
XactMice: humanizing mouse bone marrow enables microenvironment reconstitution in a patient-derived xenograft model of head and neck cancer JJ Morton, G Bird, SB Keysar, DP Astling, TR Lyons, RT Anderson, ... Oncogene 35 (3), 290-300, 2016 | 134 | 2016 |
Regulation of head and neck squamous cancer stem cells by PI3K and SOX2 SB Keysar, PN Le, B Miller, BC Jackson, JR Eagles, C Nieto, J Kim, ... Journal of the National Cancer Institute 109 (1), djw189, 2017 | 121 | 2017 |
Hedgehog signaling alters reliance on EGF receptor signaling and mediates anti-EGFR therapeutic resistance in head and neck cancer SB Keysar, PN Le, RT Anderson, JJ Morton, DW Bowles, JJ Paylor, ... Cancer research 73 (11), 3381-3392, 2013 | 104 | 2013 |
FGFR1 expression levels predict BGJ398 sensitivity of FGFR1-dependent head and neck squamous cell cancers F Göke, A Franzen, TK Hinz, LA Marek, P Yoon, R Sharma, M Bode, ... Clinical cancer research 21 (19), 4356-4364, 2015 | 98 | 2015 |
Hedgehog signaling drives radioresistance and stroma-driven tumor repopulation in head and neck squamous cancers GN Gan, J Eagles, SB Keysar, G Wang, MJ Glogowska, C Altunbas, ... Cancer research 74 (23), 7024-7036, 2014 | 73 | 2014 |
Wnt signaling dynamics in head and neck squamous cell cancer tumor‐stroma interactions PN Le, SB Keysar, B Miller, JR Eagles, TS Chimed, J Reisinger, ... Molecular carcinogenesis 58 (3), 398-410, 2019 | 56 | 2019 |
A pilot study of cetuximab and the hedgehog inhibitor IPI-926 in recurrent/metastatic head and neck squamous cell carcinoma DW Bowles, SB Keysar, JR Eagles, G Wang, MJ Glogowska, ... Oral oncology 53, 74-79, 2016 | 40 | 2016 |
The dual pathway inhibitor rigosertib is effective in direct patient tumor xenografts of head and neck squamous cell carcinomas RT Anderson, SB Keysar, DW Bowles, MJ Glogowska, DP Astling, ... Molecular cancer therapeutics 12 (10), 1994-2005, 2013 | 36 | 2013 |
Salivary gland cancer patient-derived xenografts enable characterization of cancer stem cells and new gene events associated with tumor progression SB Keysar, JR Eagles, B Miller, BC Jackson, FN Chowdhury, J Reisinger, ... Clinical Cancer Research 24 (12), 2935-2943, 2018 | 30 | 2018 |
Patterns of facial trauma before and after legalization of marijuana in Denver, Colorado: a joint study between two Denver hospitals M Sokoya, J Eagles, T Okland, D Coughlin, H Dauber, C Greenlee, ... The American Journal of Emergency Medicine 36 (5), 780-783, 2018 | 21 | 2018 |
An inducible TGF-β2-TGFβR pathway modulates the sensitivity of HNSCC cells to tyrosine kinase inhibitors targeting dominant receptor tyrosine kinases EK Kleczko, J Kim, SB Keysar, LR Heasley, JR Eagles, M Simon, ... PLoS One 10 (5), e0123600, 2015 | 12 | 2015 |
Cobimetinib: inhibiting MEK1/2 in BRAF V600-mutant melanoma. JR Eagles, A Jimeno Drugs of Today (Barcelona, Spain: 1998) 52 (11), 593-605, 2016 | 8 | 2016 |
Radiation dose uncertainty and correction for a mouse orthotopic and xenograft irradiation model GN Gan, C Altunbas, JJ Morton, J Eagles, J Backus, W Dzingle, D Raben, ... International journal of radiation biology 92 (1), 50-56, 2016 | 3 | 2016 |
Survival Impact of Local Therapy for Thyroid Carcinoma: A Surveillance, Epidemiology, and End Results Analysis W Sumner, A Amini, J McDermott, J Eagles, A Jimeno, DW Bowles, ... International Journal of Radiation Oncology, Biology, Physics 94 (4), 951, 2016 | | 2016 |
XactMice JJ Morton, G Bird, SB Keysar, DP Astling, TR Lyons, RT Anderson, ... Oncogene, 2015 | | 2015 |
Radiation Dose Uncertainty in a Mouse Head and Neck Irradiation Model GN Gan, J Eagles-Soukup, D Raben, A Jimeno, C Altunbus International Journal of Radiation Oncology, Biology, Physics 90 (1), S790, 2014 | | 2014 |
Hedgehog Pathway Mediates Head/Neck Radiation Resistance and Tumor Repopulation: Molecular Biology and Therapeutics G Gan, S Keysar, J Eagles-Soukup, R Anderson, J Morton, P Le, ... International Journal of Radiation Oncology, Biology, Physics 88 (2), 469, 2014 | | 2014 |
The Hedgehog Pathway Modulates Radiation Therapy Resistance in Head-and-Neck Cancer GN Gan, S Keysar, J Eagles-Soukup, R Anderson, C Altunbus, J Morton, ... International Journal of Radiation Oncology, Biology, Physics 87 (2), S140-S141, 2013 | | 2013 |