Paul R Thompson
Paul R Thompson
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NETs are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritis
R Khandpur, C Carmona-Rivera, A Vivekanandan-Giri, A Gizinski, ...
Science translational medicine 5 (178), 178ra40-178ra40, 2013
Regulation of the p300 HAT domain via a novel activation loop
PR Thompson, D Wang, L Wang, M Fulco, N Pediconi, D Zhang, W An, ...
Nature structural & molecular biology 11 (4), 308-315, 2004
The structural basis of protein acetylation by the p300/CBP transcriptional coactivator
X Liu, L Wang, K Zhao, PR Thompson, Y Hwang, R Marmorstein, PA Cole
Nature 451 (7180), 846-850, 2008
Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation
HD Lewis, J Liddle, JE Coote, SJ Atkinson, MD Barker, BD Bax, KL Bicker, ...
Nature chemical biology 11 (3), 189-191, 2015
Structure of an enzyme required for aminoglycoside antibiotic resistance reveals homology to eukaryotic protein kinases
WC Hon, GA McKay, PR Thompson, RM Sweet, DSC Yang, GD Wright, ...
Cell 89 (6), 887-895, 1997
Inhibitors and Inactivators of Protein Arginine Deiminase 4:  Functional and Structural Characterization,
Y Luo, K Arita, M Bhatia, B Knuckley, YH Lee, MR Stallcup, M Sato, ...
Biochemistry 45 (39), 11727-11736, 2006
Peptidylarginine deiminase inhibition is immunomodulatory and vasculoprotective in murine lupus
JS Knight, W Zhao, W Luo, V Subramanian, AA O’Dell, S Yalavarthi, ...
The Journal of clinical investigation 123 (7), 2981-2993, 2013
Diverse stimuli engage different neutrophil extracellular trap pathways
EF Kenny, A Herzig, R Krüger, A Muth, S Mondal, PR Thompson, ...
Elife 6, e24437, 2017
N-α-benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine amide, a protein arginine deiminase inhibitor, reduces the severity of murine collagen-induced arthritis
VC Willis, AM Gizinski, NK Banda, CP Causey, B Knuckley, KN Cordova, ...
The Journal of Immunology 186 (7), 4396-4404, 2011
Peptidylarginine deiminase inhibition reduces vascular damage and modulates innate immune responses in murine models of atherosclerosis
JS Knight, W Luo, AA O’Dell, S Yalavarthi, W Zhao, V Subramanian, ...
Circulation research 114 (6), 947-956, 2014
Peptidylarginine deiminase inhibition disrupts NET formation and protects against kidney, skin and vascular disease in lupus-prone MRL/lpr mice
JS Knight, V Subramanian, AA O'Dell, S Yalavarthi, W Zhao, CK Smith, ...
Annals of the rheumatic diseases 74 (12), 2199-2206, 2015
Regulation of p53 target gene expression by peptidylarginine deiminase 4
P Li, H Yao, Z Zhang, M Li, Y Luo, PR Thompson, DS Gilmour, Y Wang
Molecular and cellular biology 28 (15), 4745-4758, 2008
Protein arginine deiminase 4 (PAD4): Current understanding and future therapeutic potential
J Jones, C Causey, B Knuckley, JL Slack-Noyes, PR Thompson
Current opinion in drug discovery & development 12 (5), 616, 2009
Kinetic characterization of protein arginine deiminase 4: a transcriptional corepressor implicated in the onset and progression of rheumatoid arthritis
PL Kearney, M Bhatia, NG Jones, L Yuan, MC Glascock, KL Catchings, ...
Biochemistry 44 (31), 10570-10582, 2005
Activation of PAD4 in NET formation
A Rohrbach, D Slade, P Thompson, K Mowen
Frontiers in immunology 3, 360, 2012
Histone citrullination by protein arginine deiminase: is arginine methylation a green light or a roadblock?
PR Thompson, W Fast
ACS chemical biology 1 (7), 433-441, 2006
The protein arginine deiminases: Structure, function, inhibition, and disease
KL Bicker, PR Thompson
Biopolymers 99 (2), 155-163, 2013
Aminoglycoside phosphotransferases: proteins, structure, and mechanism
GD Wright, PR Thompson
Front Biosci 4, D9-21, 1999
Histone Arg modifications and p53 regulate the expression of OKL38, a mediator of apoptosis
H Yao, P Li, BJ Venters, S Zheng, PR Thompson, BF Pugh, Y Wang
Journal of Biological Chemistry 283 (29), 20060-20068, 2008
Transcriptional Coactivator Protein p300 Kinetic Characterization Of Its Histone Acetyltransferase Activity
PR Thompson, H Kurooka, Y Nakatani, PA Cole
Journal of Biological Chemistry 276 (36), 33721-33729, 2001
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