|NETs are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritis|
R Khandpur, C Carmona-Rivera, A Vivekanandan-Giri, A Gizinski, ...
Science translational medicine 5 (178), 178ra40-178ra40, 2013
|Regulation of the p300 HAT domain via a novel activation loop|
PR Thompson, D Wang, L Wang, M Fulco, N Pediconi, D Zhang, W An, ...
Nature structural & molecular biology 11 (4), 308-315, 2004
|The structural basis of protein acetylation by the p300/CBP transcriptional coactivator|
X Liu, L Wang, K Zhao, PR Thompson, Y Hwang, R Marmorstein, PA Cole
Nature 451 (7180), 846-850, 2008
|Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation|
HD Lewis, J Liddle, JE Coote, SJ Atkinson, MD Barker, BD Bax, KL Bicker, ...
Nature chemical biology 11 (3), 189-191, 2015
|Structure of an enzyme required for aminoglycoside antibiotic resistance reveals homology to eukaryotic protein kinases|
WC Hon, GA McKay, PR Thompson, RM Sweet, DSC Yang, GD Wright, ...
Cell 89 (6), 887-895, 1997
|Inhibitors and Inactivators of Protein Arginine Deiminase 4: Functional and Structural Characterization,|
Y Luo, K Arita, M Bhatia, B Knuckley, YH Lee, MR Stallcup, M Sato, ...
Biochemistry 45 (39), 11727-11736, 2006
|Peptidylarginine deiminase inhibition is immunomodulatory and vasculoprotective in murine lupus|
JS Knight, W Zhao, W Luo, V Subramanian, AA O’Dell, S Yalavarthi, ...
The Journal of clinical investigation 123 (7), 2981-2993, 2013
|Diverse stimuli engage different neutrophil extracellular trap pathways|
EF Kenny, A Herzig, R Krüger, A Muth, S Mondal, PR Thompson, ...
Elife 6, e24437, 2017
|N-α-benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine amide, a protein arginine deiminase inhibitor, reduces the severity of murine collagen-induced arthritis|
VC Willis, AM Gizinski, NK Banda, CP Causey, B Knuckley, KN Cordova, ...
The Journal of Immunology 186 (7), 4396-4404, 2011
|Peptidylarginine deiminase inhibition reduces vascular damage and modulates innate immune responses in murine models of atherosclerosis|
JS Knight, W Luo, AA O’Dell, S Yalavarthi, W Zhao, V Subramanian, ...
Circulation research 114 (6), 947-956, 2014
|Peptidylarginine deiminase inhibition disrupts NET formation and protects against kidney, skin and vascular disease in lupus-prone MRL/lpr mice|
JS Knight, V Subramanian, AA O'Dell, S Yalavarthi, W Zhao, CK Smith, ...
Annals of the rheumatic diseases 74 (12), 2199-2206, 2015
|Regulation of p53 target gene expression by peptidylarginine deiminase 4|
P Li, H Yao, Z Zhang, M Li, Y Luo, PR Thompson, DS Gilmour, Y Wang
Molecular and cellular biology 28 (15), 4745-4758, 2008
|Protein arginine deiminase 4 (PAD4): Current understanding and future therapeutic potential|
J Jones, C Causey, B Knuckley, JL Slack-Noyes, PR Thompson
Current opinion in drug discovery & development 12 (5), 616, 2009
|Kinetic characterization of protein arginine deiminase 4: a transcriptional corepressor implicated in the onset and progression of rheumatoid arthritis|
PL Kearney, M Bhatia, NG Jones, L Yuan, MC Glascock, KL Catchings, ...
Biochemistry 44 (31), 10570-10582, 2005
|Activation of PAD4 in NET formation|
A Rohrbach, D Slade, P Thompson, K Mowen
Frontiers in immunology 3, 360, 2012
|Histone citrullination by protein arginine deiminase: is arginine methylation a green light or a roadblock?|
PR Thompson, W Fast
ACS chemical biology 1 (7), 433-441, 2006
|The protein arginine deiminases: Structure, function, inhibition, and disease|
KL Bicker, PR Thompson
Biopolymers 99 (2), 155-163, 2013
|Aminoglycoside phosphotransferases: proteins, structure, and mechanism|
GD Wright, PR Thompson
Front Biosci 4, D9-21, 1999
|Histone Arg modifications and p53 regulate the expression of OKL38, a mediator of apoptosis|
H Yao, P Li, BJ Venters, S Zheng, PR Thompson, BF Pugh, Y Wang
Journal of Biological Chemistry 283 (29), 20060-20068, 2008
|Transcriptional Coactivator Protein p300 Kinetic Characterization Of Its Histone Acetyltransferase Activity|
PR Thompson, H Kurooka, Y Nakatani, PA Cole
Journal of Biological Chemistry 276 (36), 33721-33729, 2001