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A.T. Maynard
A.T. Maynard
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Verified email at creodecode.com - Homepage
Title
Cited by
Cited by
Year
Reactivity of the HIV-1 nucleocapsid protein p7 zinc finger domains from the perspective of density-functional theory
AT Maynard, M Huang, WG Rice, DG Covell
Proceedings of the National Academy of Sciences 95 (20), 11578-11583, 1998
4161998
Anti-HIV agents that selectively target retroviral nucleocapsid protein zinc fingers without affecting cellular zinc finger proteins
M Huang, A Maynard, JA Turpin, L Graham, GM Janini, DG Covell, ...
Journal of medicinal chemistry 41 (9), 1371-1381, 1998
1831998
Reactivity of zinc finger cores: analysis of protein packing and electrostatic screening
AT Maynard, DG Covell
Journal of the American Chemical Society 123 (6), 1047-1058, 2001
1772001
Synthesis and biological properties of novel pyridinioalkanoyl thiolesters (PATE) as anti-HIV-1 agents that target the viral nucleocapsid protein zinc fingers
JA Turpin, Y Song, JK Inman, M Huang, A Wallqvist, A Maynard, ...
Journal of medicinal chemistry 42 (1), 67-86, 1999
1471999
Suppression of breast cancer by chemical modulation of vulnerable zinc fingers in estrogen receptor
LH Wang, XY Yang, X Zhang, K Mihalic, YX Fan, W Xiao, OMZ Howard, ...
Nature medicine 10 (1), 40-47, 2004
1012004
Naturally occurring CCR5 extracellular and transmembrane domain variants affect HIV-1 Co-receptor and ligand binding function
OMZ Howard, AK Shirakawa, JA Turpin, A Maynard, GJ Tobin, ...
Journal of Biological Chemistry 274 (23), 16228-16234, 1999
941999
Targeting the NS5A protein of HCV: an emerging option
DG Cordek, JT Bechtel, AT Maynard, WM Kazmierski, CE Cameron
Drugs of the Future 36 (9), 691, 2011
602011
An Ab initio study of the relationship between nitroarene mutagenicity and electron affinity.
AT Maynard, LG Pedersen, HS Posner, JD McKinney
Molecular pharmacology 29 (6), 629-636, 1986
561986
Discovery of a potent boronic acid derived inhibitor of the HCV RNA-dependent RNA polymerase
A Maynard, RM Crosby, B Ellis, R Hamatake, Z Hong, BA Johns, ...
Journal of Medicinal Chemistry 57 (5), 1902-1913, 2014
552014
Novel spiroketal pyrrolidine GSK2336805 potently inhibits key hepatitis C virus genotype 1b mutants: from lead to clinical compound
WM Kazmierski, A Maynard, M Duan, S Baskaran, J Botyanszki, R Crosby, ...
Journal of Medicinal Chemistry 57 (5), 2058-2073, 2014
542014
Design of N-Benzoxaborole Benzofuran GSK8175—Optimization of Human Pharmacokinetics Inspired by Metabolites of a Failed Clinical HCV Inhibitor
PY Chong, JB Shotwell, J Miller, DJ Price, A Maynard, C Voitenleitner, ...
Journal of Medicinal Chemistry 62 (7), 3254-3267, 2019
512019
A quantum dynamical study of CH overtones in fluoroform. II. Eigenstate analysis of the and regions
A Maynard, RE Wyatt, C Iung
The Journal of chemical physics 106 (23), 9483-9496, 1997
461997
A quantum dynamical study of CH overtones in fluoroform. I. A nine‐dimensional ab initio surface, vibrational spectra and dynamics
AT Maynard, RE Wyatt, C Iung
The Journal of chemical physics 103 (19), 8372-8390, 1995
43*1995
Quantifying, visualizing, and monitoring lead optimization
AT Maynard, CD Roberts
Journal of Medicinal Chemistry 59 (9), 4189-4201, 2016
332016
Inhibitors of ion channels
BE Marron, PC Fritch, CJ Markworth, AT Maynard, NA Swain
US Patent 8,741,934, 2014
31*2014
Small molecule inhibition of RAS/MAPK signaling ameliorates developmental pathologies of Kabuki Syndrome
IC Tsai, K McKnight, SU McKinstry, AT Maynard, PL Tan, C Golzio, ...
Scientific reports 8 (1), 10779, 2018
302018
Design and synthesis of spirocyclic compounds as HCV replication inhibitors by targeting viral NS4B protein
VWF Tai, D Garrido, DJ Price, A Maynard, JJ Pouliot, Z Xiong, JW Seal III, ...
Bioorganic & medicinal chemistry letters 24 (10), 2288-2294, 2014
272014
Comparison of the specificity of interaction of cellular and viral zinc-binding domains with 2-mercaptobenzamide thioesters
LMM Jenkins, SR Durell, AT Maynard, SJ Stahl, JK Inman, E Appella, ...
Journal of the American Chemical Society 128 (36), 11964-11976, 2006
252006
Matrix Isolation Infrared and ab Initio Study of the 1:1 Complexes of Bromocyclopropane with NH3 and (CH3)3N:  Evidence for a Novel C−H···N Hydrogen Bond
BL Bedell, L Goldfarb, ER Mysak, C Samet, A Maynard
The Journal of Physical Chemistry A 103 (23), 4572-4579, 1999
251999
Statistical tools for virtual screening
JR Krumrine, AT Maynard, CL Lerman
Journal of medicinal chemistry 48 (23), 7477-7481, 2005
162005
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