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Kevin Bredemeyer
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Evolutionary constraint and innovation across hundreds of placental mammals
MJ Christmas, IM Kaplow, DP Genereux, MX Dong, GM Hughes, X Li, ...
Science 380 (6643), eabn3943, 2023
632023
A genomic timescale for placental mammal evolution
NM Foley, VC Mason, AJ Harris, KR Bredemeyer, J Damas, HA Lewin, ...
Science 380 (6643), eabl8189, 2023
412023
Integrating gene annotation with orthology inference at scale
BM Kirilenko, C Munegowda, E Osipova, D Jebb, V Sharma, M Blumer, ...
Science 380 (6643), eabn3107, 2023
362023
Leveraging base-pair mammalian constraint to understand genetic variation and human disease
PF Sullivan, JRS Meadows, S Gazal, BDN Phan, X Li, DP Genereux, ...
Science 380 (6643), eabn2937, 2023
342023
Phylogenomics and the genetic architecture of the placental mammal radiation
WJ Murphy, NM Foley, KR Bredemeyer, J Gatesy, MS Springer
Annual Review of Animal Biosciences 9, 29-53, 2021
342021
Ultracontinuous Single Haplotype Genome Assemblies for the Domestic Cat (Felis catus) and Asian Leopard Cat (Prionailurus bengalensis)
KR Bredemeyer, AJ Harris, G Li, L Zhao, NM Foley, M Roelke-Parker, ...
Journal of Heredity 112 (2), 165-173, 2021
322021
Three-dimensional genome rewiring in loci with human accelerated regions
KC Keough, S Whalen, F Inoue, PF Przytycki, T Fair, C Deng, M Steyert, ...
Science 380 (6643), eabm1696, 2023
262023
Insights into mammalian TE diversity through the curation of 248 genome assemblies
AB Osmanski, NS Paulat, J Korstian, JR Grimshaw, M Halsey, ...
Science 380 (6643), eabn1430, 2023
242023
Mammalian evolution of human cis-regulatory elements and transcription factor binding sites
G Andrews, K Fan, HE Pratt, N Phalke, Zoonomia Consortium §, ...
Science 380 (6643), eabn7930, 2023
232023
Relating enhancer genetic variation across mammals to complex phenotypes using machine learning
IM Kaplow, AJ Lawler, DE Schäffer, C Srinivasan, HH Sestili, ME Wirthlin, ...
Science 380 (6643), eabm7993, 2023
232023
The contribution of historical processes to contemporary extinction risk in placental mammals
AP Wilder, MA Supple, A Subramanian, A Mudide, R Swofford, ...
Science 380 (6643), eabn5856, 2023
222023
Genomic architecture constrained placental mammal X Chromosome evolution
WA Brashear, KR Bredemeyer, WJ Murphy
Genome Research 31 (8), 1353-1365, 2021
162021
The functional and evolutionary impacts of human-specific deletions in conserved elements
JR Xue, A Mackay-Smith, K Mouri, MF Garcia, MX Dong, JF Akers, ...
Science 380 (6643), eabn2253, 2023
152023
An ASO therapy for Angelman syndrome that targets an evolutionarily conserved region at the start of the UBE3A-AS transcript
SV Dindot, S Christian, WJ Murphy, A Berent, J Panagoulias, A Schlafer, ...
Science Translational Medicine 15 (688), eabf4077, 2023
112023
Rapid macrosatellite evolution promotes X-linked hybrid male sterility in a feline interspecies cross
KR Bredemeyer, CM Seabury, MJ Stickney, JR McCarrey, BM VonHoldt, ...
Molecular biology and evolution 38 (12), 5588-5609, 2021
82021
Single-haplotype comparative genomics provides insights into lineage-specific structural variation during cat evolution
KR Bredemeyer, LD Hillier, AJ Harris, GM Hughes, NM Foley, C Lawless, ...
Nature genetics 55 (11), 1953-1963, 2023
62023
Comparative genomics of Balto, a famous historic dog, captures lost diversity of 1920s sled dogs
KL Moon, HJ Huson, K Morrill, MS Wang, X Li, K Srikanth, ...
Science 380 (6643), eabn5887, 2023
62023
Springer MS and Murphy WJ. 2023. A genomic timescale for placental mammal evolution
NM Foley, VC Mason, AJ Harris, KR Bredemeyer, J Damas, HA Lewin, ...
Science 380, 1-9, 0
6
Vocal learning-associated convergent evolution in mammalian proteins and regulatory elements
ME Wirthlin, TA Schmid, JE Elie, X Zhang, A Kowalczyk, R Redlich, ...
Science, eabn3263, 2024
52024
Development of an ASO therapy for Angelman syndrome by targeting an evolutionarily conserved region at the start of the UBE3A-AS transcript
SV Dindot, S Christian, WJ Murphy, A Berent, J Panagoulias, A Schlafer, ...
bioRxiv, 2021.07. 27.453820, 2021
42021
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