Partial inhibition of Cdk1 in G2 phase overrides the SAC and decouples mitotic events RA McCloy, S Rogers, CE Caldon, T Lorca, A Castro, A Burgess Cell cycle 13 (9), 1400-1412, 2014 | 960 | 2014 |
Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis C Vennin, VT Chin, SC Warren, MC Lucas, D Herrmann, A Magenau, ... Science translational medicine 9 (384), eaai8504, 2017 | 238 | 2017 |
Tamoxifen-induced epigenetic silencing of oestrogen-regulated genes in anti-hormone resistant breast cancer A Stone, F Valdes-Mora, JMW Gee, L Farrow, RA McClelland, H Fiegl, ... Plos one 7 (7), e40466, 2012 | 75 | 2012 |
Global phosphoproteomic mapping of early mitotic exit in human cells identifies novel substrate dephosphorylation motifs RA McCloy, BL Parker, S Rogers, R Chaudhuri, V Gayevskiy, NJ Hoffman, ... Molecular & Cellular Proteomics 14 (8), 2194-2212, 2015 | 67 | 2015 |
The role of canonical and non-canonical Hedgehog signaling in tumor progression in a mouse model of small cell lung cancer A Szczepny, S Rogers, WSN Jayasekara, K Park, RA McCloy, ... Oncogene 36 (39), 5544-5550, 2017 | 63 | 2017 |
PP1 initiates the dephosphorylation of MASTL, triggering mitotic exit and bistability in human cells S Rogers, D Fey, RA McCloy, BL Parker, NJ Mitchell, RJ Payne, RJ Daly, ... Journal of cell science 129 (7), 1340-1354, 2016 | 60 | 2016 |
MASTL overexpression promotes chromosome instability and metastasis in breast cancer S Rogers, RA McCloy, BL Parker, D Gallego-Ortega, AMK Law, VT Chin, ... Oncogene 37 (33), 4518-4533, 2018 | 56 | 2018 |
BCL-2 hypermethylation is a potential biomarker of sensitivity to antimitotic chemotherapy in endocrine-resistant breast cancer A Stone, MJ Cowley, F Valdes-Mora, RA McCloy, CM Sergio, ... Molecular cancer therapeutics 12 (9), 1874-1885, 2013 | 56 | 2013 |
Global characterization of signalling networks associated with tamoxifen resistance in breast cancer BC Browne, F Hochgräfe, J Wu, EKA Millar, J Barraclough, A Stone, ... The FEBS journal 280 (21), 5237-5257, 2013 | 48 | 2013 |
Inhibition of activin signaling in lung adenocarcinoma increases the therapeutic index of platinum chemotherapy KD Marini, DR Croucher, RA McCloy, V Vaghjiani, A Gonzalez-Rajal, ... Science translational medicine 10 (451), eaat3504, 2018 | 43 | 2018 |
Identification of PUMA as an estrogen target gene that mediates the apoptotic response to tamoxifen in human breast cancer cells and predicts patient outcome and tamoxifen … CG Roberts, EKA Millar, SA O'Toole, CM McNeil, GM Lehrbach, M Pinese, ... Oncogene 30 (28), 3186-3197, 2011 | 43 | 2011 |
Transcriptomic and proteomic retinal pigment epithelium signatures of age-related macular degeneration A Senabouth, M Daniszewski, GE Lidgerwood, HH Liang, D Hernández, ... Nature Communications 13 (1), 4233, 2022 | 34 | 2022 |
The E3 ubiquitin ligase UBR5 regulates centriolar satellite stability and primary cilia RF Shearer, KAM Frikstad, J McKenna, RA McCloy, N Deng, A Burgess, ... Molecular biology of the cell 29 (13), 1542-1554, 2018 | 32 | 2018 |
The tumor suppressor Hic1 maintains chromosomal stability independent of Tp53 A Szczepny, K Carey, L McKenzie, WSN Jayasekara, F Rossello, ... Oncogene 37 (14), 1939-1948, 2018 | 29 | 2018 |
Mechanisms regulating phosphatase specificity and the removal of individual phosphorylation sites during mitotic exit S Rogers, R McCloy, DN Watkins, A Burgess Bioessays 38, S24-S32, 2016 | 28 | 2016 |
Deep multi-region whole-genome sequencing reveals heterogeneity and gene-by-environment interactions in treatment-naive, metastatic lung cancer TL Leong, V Gayevskiy, DP Steinfort, MR De Massy, A Gonzalez-Rajal, ... Oncogene 38 (10), 1661-1675, 2019 | 27 | 2019 |
Role of endoplasmic reticulum stress induction by the plant toxin, persin, in overcoming resistance to the apoptotic effects of tamoxifen in human breast cancer cells RA McCloy, EJ Shelley, CG Roberts, E Boslem, TJ Biden, RI Nicholson, ... British journal of cancer 109 (12), 3034-3041, 2013 | 19 | 2013 |
A non-genetic, cell cycle-dependent mechanism of platinum resistance in lung adenocarcinoma A Gonzalez Rajal, KA Marzec, RA McCloy, M Nobis, V Chin, JF Hastings, ... Elife 10, e65234, 2021 | 15 | 2021 |
Australian Pancreatic Cancer Genome Initiative (APGI) Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and … C Vennin, VT Chin, SC Warren, MC Lucas, D Herrmann, A Magenau, ... Science Translational Medicine 9, 2017 | 12 | 2017 |
Print CG, Clark SJ, Musgrove EA. BCL-2 hypermethylation is a potential biomarker of sensitivity to antimitotic chemotherapy in endocrine-resistant breast cancer A Stone, MJ Cowley, F Valdes-Mora, RA McCloy, CM Sergio, ... Mol Cancer Ther 12 (9), 1874-85, 2013 | 12 | 2013 |