Synthesis and function of 3-phosphorylated inositol lipids B Vanhaesebroeck, SJ Leevers, K Ahmadi, J Timms, R Katso, PC Driscoll, ... Annual review of biochemistry 70 (1), 535-602, 2001 | 2145 | 2001 |
The extended protein kinase C superfamily H MELLOR, PJ PARKER Biochemical Journal 332 (2), 281-292, 1998 | 2096 | 1998 |
Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1 JA Le Good, WH Ziegler, DB Parekh, DR Alessi, P Cohen, PJ Parker Science 281 (5385), 2042-2045, 1998 | 1439 | 1998 |
Multiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signaling pathways L Coussens, PJ Parker, L Rhee, TL Yang-Feng, E Chen, MD Waterfield, ... Science 233 (4766), 859-866, 1986 | 1360 | 1986 |
Protein kinase C-a question of specificity LV Dekker, PJ Parker Trends in biochemical sciences 19 (2), 73-77, 1994 | 1255 | 1994 |
The complete primary structure of protein kinase C—the major phorbol ester receptor PJ Parker, L Coussens, N Totty, L Rhee, S Young, E Chen, S Stabel, ... Science 233 (4766), 853-859, 1986 | 1088 | 1986 |
Activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway by conventional, novel, and atypical protein kinase C isotypes DC Schönwasser, RM Marais, CJ Marshall, PJ Parker Molecular and cellular biology, 1998 | 971 | 1998 |
Autophosphorylation sites on the epidermal growth factor receptor J Downward, P Parker, MD Waterfield Nature 311 (5985), 483-485, 1984 | 959 | 1984 |
Phosphatidylinositol 3-kinase: structure and expression of the 110 kd catalytic subunit ID Hiles, M Otsu, S Volinia, MJ Fry, I Gout, R Dhand, G Panayotou, ... Cell 70 (3), 419-429, 1992 | 913 | 1992 |
Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase M Otsu, I Hiles, I Gout, MJ Fry, F Ruiz-Larrea, G Panayotou, A Thompson, ... Cell 65 (1), 91-104, 1991 | 913 | 1991 |
Carboplatin in BRCA1/2-mutated and triple-negative breast cancer BRCAness subgroups: the TNT Trial A Tutt, H Tovey, MCU Cheang, S Kernaghan, L Kilburn, P Gazinska, ... Nature medicine 24 (5), 628-637, 2018 | 863 | 2018 |
Isozyme-selective stimulation of phospholipase C-β2 by G protein βγ-subunits M Camps, A Carozzi, P Schnabel, A Scheer, PJ Parker, P Gierschik Nature 360 (6405), 684-686, 1992 | 832 | 1992 |
Multiple pathways control protein kinase C phosphorylation DB Parekh, W Ziegler, PJ Parker The EMBO journal, 2000 | 748 | 2000 |
Isoenzyme specificity of bisindolylmaleimides, selective inhibitors of protein kinase C SE Wilkinson, PJ Parker, JS Nixon Biochemical Journal 294 (2), 335-337, 1993 | 626 | 1993 |
Protein kinase C S Stabel, PJ Parker Pharmacology & therapeutics 51 (1), 71-95, 1991 | 622 | 1991 |
Osmotic stress activates phosphatidylinositol-3, 5-bisphosphate synthesis SK Dove, FT Cooke, MR Douglas, LG Sayers, PJ Parker, RH Michell Nature 390 (6656), 187-192, 1997 | 588 | 1997 |
Down-regulation of protein kinase C is due to an increased rate of degradation S Young, PJ Parker, A Ullrich, S Stabel Biochemical Journal 244 (3), 775-779, 1987 | 560 | 1987 |
PKC and the control of localized signal dynamics C Rosse, M Linch, S Kermorgant, AJM Cameron, K Boeckeler, PJ Parker Nature reviews Molecular cell biology 11 (2), 103-112, 2010 | 548 | 2010 |
Specific involvement of PKC-ε in sensitization of the neuronal response to painful heat P Cesare, LV Dekker, A Sardini, PJ Parker, PA McNaughton Neuron 23 (3), 617-624, 1999 | 507 | 1999 |
Differential regulation of glycogen synthase kinase-3 beta by protein kinase C isotypes. N Goode, K Hughes, JR Woodgett, PJ Parker Journal of Biological Chemistry 267 (24), 16878-16882, 1992 | 500 | 1992 |