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Andrew Sharp
Andrew Sharp
University of Manchester
Verified email at evotec.com - Homepage
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Cited by
Year
Pharmacokinetics and pharmacodynamics of posaconazole for invasive pulmonary aspergillosis: clinical implications for antifungal therapy
SJ Howard, JM Lestner, A Sharp, L Gregson, J Goodwin, J Slater, ...
Journal of Infectious Diseases 203 (9), 1324-1332, 2011
1172011
In vitro activity of a new triazole BAL4815, the active component of BAL8557 (the water-soluble prodrug), against Aspergillus spp.
PA Warn, A Sharp, DW Denning
Journal of Antimicrobial Chemotherapy 57 (1), 135-138, 2006
1072006
Pharmacokinetics and pharmacodynamics of a novel triazole, isavuconazole: mathematical modeling, importance of tissue concentrations, and impact of immune status on antifungal …
PA Warn, A Sharp, A Parmar, J Majithiya, DW Denning, WW Hope
Antimicrobial agents and chemotherapy 53 (8), 3453-3461, 2009
972009
Impact of bolus dosing versus continuous infusion of piperacillin and tazobactam on the development of antimicrobial resistance in Pseudomonas aeruginosa
TW Felton, J Goodwin, L O'Connor, A Sharp, L Gregson, J Livermore, ...
Antimicrobial agents and chemotherapy 57 (12), 5811-5819, 2013
932013
Infrared body temperature measurement of mice as an early predictor of death in experimental fungal infections
PA Warn, MW Brampton, A Sharp, G Morrissey, N Steel, DW Denning, ...
Laboratory Animals 37 (2), 126-131, 2003
902003
In vitro interaction of terbinafine with itraconazole, fluconazole, amphotericin B and 5-flucytosine against Aspergillus spp.
J Mosquera, A Sharp, CB Moore, PA Warn, DW Denning
Journal of Antimicrobial Chemotherapy 50 (2), 189-194, 2002
902002
Comparative in vivo activity of BAL4815, the active component of the prodrug BAL8557, in a neutropenic murine model of disseminated Aspergillus flavus
PA Warn, A Sharp, J Mosquera, J Spickermann, A Schmitt-Hoffmann, ...
Journal of antimicrobial chemotherapy 58 (6), 1198-1207, 2006
862006
Peroral amphotericin B polymer nanoparticles lead to comparable or superior in vivo antifungal activity to that of intravenous Ambisome® or Fungizone™
JL Italia, A Sharp, KC Carter, P Warn, MNVR Kumar
PloS one 6 (10), e25744, 2011
742011
Efficacy of isavuconazole, voriconazole and fluconazole in temporarily neutropenic murine models of disseminated Candida tropicalis and Candida krusei
J Majithiya, A Sharp, A Parmar, DW Denning, PA Warn
Journal of Antimicrobial Chemotherapy 63 (1), 161-166, 2009
722009
Infection augments expression of mechanosensing Piezo1 channels in amyloid plaque-reactive astrocytes
M Velasco-Estevez, M Mampay, H Boutin, A Chaney, P Warn, A Sharp, ...
Frontiers in aging neuroscience 10, 332, 2018
692018
Pharmacokinetics and Pharmacodynamics of Fluconazole for Cryptococcal Meningoencephalitis: Implications for Antifungal Therapy and In Vitro Susceptibility …
A Sudan, J Livermore, SJ Howard, Z Al-Nakeeb, A Sharp, J Goodwin, ...
Antimicrobial agents and chemotherapy 57 (6), 2793-2800, 2013
692013
The efficacy of aerosol treatment with non-ionic surfactant vesicles containing amphotericin B in rodent models of leishmaniasis and pulmonary aspergillosis infection
M Alsaadi, JL Italia, AB Mullen, MNVR Kumar, AA Candlish, ...
Journal of controlled release 160 (3), 685-691, 2012
662012
Effect of neutropenia and treatment delay on the response to antifungal agents in experimental disseminated candidiasis
WW Hope, GL Drusano, CB Moore, A Sharp, A Louie, TJ Walsh, ...
Antimicrobial agents and chemotherapy 51 (1), 285-295, 2007
622007
Effect of neutropenia and treatment delay on the response to antifungal agents in experimental disseminated candidiasis
WW Hope, GL Drusano, CB Moore, A Sharp, A Louie, TJ Walsh, ...
Antimicrobial agents and chemotherapy 51 (1), 285-295, 2007
622007
Streptococcus pneumoniae worsens cerebral ischemia via interleukin 1 and platelet glycoprotein Ibα
Á Dénes, JM Pradillo, C Drake, A Sharp, P Warn, KN Murray, B Rohit, ...
Annals of neurology 75 (5), 670-683, 2014
602014
Pharmacodynamics of liposomal amphotericin B and flucytosine for cryptococcal meningoencephalitis: safe and effective regimens for immunocompromised patients
L O'Connor, J Livermore, AD Sharp, J Goodwin, L Gregson, SJ Howard, ...
The Journal of infectious diseases 208 (2), 351-361, 2013
582013
Disseminated candidiasis caused by Candida albicans with amino acid substitutions in Fks1 at position Ser645 cannot be successfully treated with micafungin
JL Slater, SJ Howard, A Sharp, J Goodwin, LM Gregson, ...
Antimicrobial agents and chemotherapy 55 (7), 3075-3083, 2011
582011
Derivation of an In Vivo Drug Exposure Breakpoint for Flucytosine against Candida albicans and Impact of the MIC, Growth Rate, and Resistance Genotype on the …
WW Hope, PA Warn, A Sharp, S Howard, M Kasai, A Louie, TJ Walsh, ...
Antimicrobial agents and chemotherapy 50 (11), 3680-3688, 2006
502006
Effect of hypoxic conditions on in vitro susceptibility testing of amphotericin B, itraconazole and micafungin against Aspergillus and Candida
PA Warn, A Sharp, J Guinea, DW Denning
Journal of Antimicrobial Chemotherapy 53 (5), 743-749, 2004
502004
Pharmacodynamics of echinocandins against Candida glabrata: requirement for dosage escalation to achieve maximal antifungal activity in neutropenic hosts
SJ Howard, J Livermore, A Sharp, J Goodwin, L Gregson, ...
Antimicrobial agents and chemotherapy 55 (10), 4880-4887, 2011
472011
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