Enzo Medico
Enzo Medico
Professor of Histology, University of Torino and Head of the Laboratory of Oncogenomics, Candiolo
Verified email at ircc.it
TitleCited byYear
Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer
S Misale, R Yaeger, S Hobor, E Scala, M Janakiraman, D Liska, E Valtorta, ...
Nature 486 (7404), 532, 2012
12162012
Expression of the Met/HGF receptor in normal and neoplastic human tissues.
MFR Di, RP Narsimhan, M Olivero, S Bretti, S Giordano, E Medico, ...
Oncogene 6 (11), 1997-2003, 1991
5861991
A molecularly annotated platform of patient-derived xenografts (“xenopatients”) identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancer
A Bertotti, G Migliardi, F Galimi, F Sassi, D Torti, C Isella, D Corà, ...
Cancer discovery 1 (6), 508-523, 2011
5632011
Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients
G Siravegna, B Mussolin, M Buscarino, G Corti, A Cassingena, ...
Nature medicine 21 (7), 795, 2015
4702015
FLAME, a novel fuzzy clustering method for the analysis of DNA microarray data
L Fu, E Medico
BMC bioinformatics 8 (1), 3, 2007
3902007
Stromal contribution to the colorectal cancer transcriptome
C Isella, A Terrasi, SE Bellomo, C Petti, G Galatola, A Muratore, A Mellano, ...
Nature genetics 47 (4), 312, 2015
2942015
The MET oncogene drives a genetic programme linking cancer to haemostasis
C Boccaccio, G Sabatino, E Medico, F Girolami, A Follenzi, G Reato, ...
Nature 434 (7031), 396, 2005
2602005
Induction of MET by ionizing radiation and its role in radioresistance and invasive growth of cancer
F De Bacco, P Luraghi, E Medico, G Reato, F Girolami, T Perera, ...
JNCI: Journal of the National Cancer Institute 103 (8), 645-661, 2011
2482011
Promoter trapping reveals significant differences in integration site selection between MLV and HIV vectors in primary hematopoietic cells
M De Palma, E Montini, FRS De Sio, F Benedicenti, A Gentile, E Medico, ...
Blood 105 (6), 2307-2315, 2005
1932005
Neural differentiation of human mesenchymal stem cells: Evidence for expression of neural markers and eag K+ channel types
K Mareschi, M Novara, D Rustichelli, I Ferrero, D Guido, E Carbone, ...
Experimental hematology 34 (11), 1563-1572, 2006
1872006
Interrogating open issues in cancer precision medicine with patient-derived xenografts
AT Byrne, DG Alférez, F Amant, D Annibali, J Arribas, AV Biankin, A Bruna, ...
Nature Reviews Cancer 17 (4), 254, 2017
1742017
Transfer of motogenic and invasive response to scatter factor/hepatocyte growth factor by transfection of human MET protooncogene.
S Giordano, Z Zhen, E Medico, G Gaudino, F Galimi, PM Comoglio
Proceedings of the National Academy of Sciences 90 (2), 649-653, 1993
1651993
The tyrosine kinase receptors Ron and Sea control" scattering" and morphogenesis of liver progenitor cells in vitro.
E Medico, AM Mongiovi, J Huff, MA Jelinek, A Follenzi, G Gaudino, ...
Molecular biology of the cell 7 (4), 495-504, 1996
1521996
Phosphorylation of serine 985 negatively regulates the hepatocyte growth factor receptor kinase.
L Gandino, P Longati, E Medico, M Prat, PM Comoglio
Journal of Biological Chemistry 269 (3), 1815-1820, 1994
1461994
Gene expression profiling uncovers molecular classifiers for the recognition of anaplastic large-cell lymphoma within peripheral T-cell neoplasms
R Piva, L Agnelli, E Pellegrino, K Todoerti, V Grosso, I Tamagno, ...
J Clin Oncol 28 (9), 1583-1590, 2010
1392010
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets
E Medico, M Russo, G Picco, C Cancelliere, E Valtorta, G Corti, ...
Nature communications 6, 7002, 2015
1252015
The MET oncogene is a functional marker of a glioblastoma stem cell subtype
F De Bacco, E Casanova, E Medico, S Pellegatta, F Orzan, R Albano, ...
Cancer research 72 (17), 4537-4550, 2012
1122012
Genetic and expression analysis of MET, MACC1, and HGF in metastatic colorectal cancer: response to met inhibition in patient xenografts and pathologic correlations
F Galimi, D Torti, F Sassi, C Isella, D Corà, S Gastaldi, D Ribero, ...
Clinical cancer research 17 (10), 3146-3156, 2011
1082011
Osteopontin is an autocrine mediator of hepatocyte growth factor-induced invasive growth
E Medico, A Gentile, CL Celso, TA Williams, G Gambarotta, L Trusolino, ...
Cancer research 61 (15), 5861-5868, 2001
1042001
The thioxotriazole copper (II) complex A0 induces endoplasmic reticulum stress and paraptotic death in human cancer cells
S Tardito, C Isella, E Medico, L Marchio, E Bevilacqua, M Hatzoglou, ...
Journal of Biological Chemistry 284 (36), 24306-24319, 2009
992009
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