| An early haematopoietic defect in mice lacking the transcription factor GATA-2 FY Tsai, G Keller, FC Kuo, M Weiss, J Chen, M Rosenblatt, FW Alt, ... Nature 371 (6494), 221-226, 1994 | 1792 | 1994 |
| Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment DM Willerford, J Chen, JA Ferry, L Davidson, A Ma, FW Alt Immunity 3 (4), 521-530, 1995 | 1377 | 1995 |
| Densely interconnected transcriptional circuits control cell states in human hematopoiesis N Novershtern, A Subramanian, LN Lawton, RH Mak, WN Haining, ... Cell 144 (2), 296-309, 2011 | 1085 | 2011 |
| RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription Q Ge, MT McManus, T Nguyen, CH Shen, PA Sharp, HN Eisen, J Chen Proceedings of the National Academy of Sciences 100 (5), 2718-2723, 2003 | 757 | 2003 |
| Immunoglobulin gene rearrangement in B cell deficient mice generated by targeted deletion of the JH locus J Chen, M Trounstine, FW Alt, F Young, C Kurahara, JF Loring, D Huszar International immunology 5 (6), 647-656, 1993 | 716 | 1993 |
| B-1 and B-2 cell–derived immunoglobulin M antibodies are nonredundant components of the protective response to influenza virus infection N Baumgarth, OC Herman, GC Jager, LE Brown, LA Herzenberg, J Chen The Journal of experimental medicine 192 (2), 271-280, 2000 | 701 | 2000 |
| Homeostasis-stimulated proliferation drives naive T cells to differentiate directly into memory T cells BK Cho, VP Rao, Q Ge, HN Eisen, J Chen The Journal of experimental medicine 192 (4), 549-556, 2000 | 698 | 2000 |
| A critical role of natural immunoglobulin M in immediate defense against systemic bacterial infection M Boes, AP Prodeus, T Schmidt, MC Carroll, J Chen The Journal of experimental medicine 188 (12), 2381-2386, 1998 | 695 | 1998 |
| Inhibition of influenza virus production in virus-infected mice by RNA interference Q Ge, L Filip, A Bai, T Nguyen, HN Eisen, J Chen Proceedings of the national academy of sciences 101 (23), 8676-8681, 2004 | 655 | 2004 |
| CAR-NK cells: A promising cellular immunotherapy for cancer G Xie, H Dong, Y Liang, JD Ham, R Rizwan, J Chen EBioMedicine 59, 2020 | 619 | 2020 |
| Gene silencing using micro-RNA designed hairpins MT McManus, CP Petersen, BB Haines, J Chen, PA Sharp Rna 8 (6), 842-850, 2002 | 575 | 2002 |
| VDJ recombination FW Alt, EM Oltz, F Young, J Gorman, G Taccioli, J Chen Immunology today 13 (8), 306-314, 1992 | 537 | 1992 |
| T-cell engagement of dendritic cells rapidly rearranges MHC class II transport M Boes, J Cerny, R Massol, M Op den Brouw, T Kirchhausen, J Chen, ... Nature 418 (6901), 983-988, 2002 | 488 | 2002 |
| RAG-2-deficient blastocyst complementation: an assay of gene function in lymphocyte development. J Chen, R Lansford, V Stewart, F Young, FW Alt Proceedings of the National Academy of Sciences 90 (10), 4528-4532, 1993 | 485 | 1993 |
| Full deacylation of polyethylenimine dramatically boosts its gene delivery efficiency and specificity to mouse lung M Thomas, JJ Lu, Q Ge, C Zhang, J Chen, AM Klibanov Proceedings of the National Academy of Sciences 102 (16), 5679-5684, 2005 | 470 | 2005 |
| Accelerated development of IgG autoantibodies and autoimmune disease in the absence of secreted IgM M Boes, T Schmidt, K Linkemann, BC Beaudette, A Marshak-Rothstein, ... Proceedings of the National Academy of Sciences 97 (3), 1184-1189, 2000 | 467 | 2000 |
| Enhanced B-1 cell development, but impaired IgG antibody responses in mice deficient in secreted IgM M Boes, C Esau, MB Fischer, T Schmidt, M Carroll, J Chen The Journal of Immunology 160 (10), 4776-4787, 1998 | 388 | 1998 |
| B cell development in mice that lack one or both immunoglobulin kappa light chain genes. J Chen, M Trounstine, C Kurahara, F Young, CC Kuo, Y Xu, JF Loring, ... The EMBO journal 12 (3), 821-830, 1993 | 373 | 1993 |
| AB cell-based sensor for rapid identification of pathogens TH Rider, MS Petrovick, FE Nargi, JD Harper, ED Schwoebel, ... Science 301 (5630), 213-215, 2003 | 365 | 2003 |
| Polymeric coatings that inactivate both influenza virus and pathogenic bacteria J Haldar, D An, L Álvarez de Cienfuegos, J Chen, AM Klibanov Proceedings of the National Academy of Sciences 103 (47), 17667-17671, 2006 | 352 | 2006 |
