Rho-associated kinase (ROCK) function is essential for cell cycle progression, senescence and tumorigenesis S Kümper, FK Mardakheh, A McCarthy, M Yeo, GW Stamp, A Paul, ... elife 5, e12203, 2016 | 160 | 2016 |
Rho kinase inhibitors block melanoma cell migration and inhibit metastasis A Sadok, A McCarthy, J Caldwell, I Collins, MD Garrett, M Yeo, S Hooper, ... Cancer research 75 (11), 2272-2284, 2015 | 146 | 2015 |
Microenvironmental heterogeneity parallels breast cancer progression: a histology–genomic integration analysis R Natrajan, H Sailem, FK Mardakheh, M Arias Garcia, CJ Tape, ... PLoS medicine 13 (2), e1001961, 2016 | 129 | 2016 |
Global analysis of mRNA, translation, and protein localization: local translation is a key regulator of cell protrusions FK Mardakheh, A Paul, S Kümper, A Sadok, H Paterson, A Mccarthy, ... Developmental cell 35 (3), 344-357, 2015 | 118 | 2015 |
The deleted in brachydactyly B domain of ROR2 is required for receptor activation by recruitment of Src S Akbarzadeh, LM Wheldon, SMM Sweet, S Talma, FK Mardakheh, ... PloS one 3 (3), e1873, 2008 | 89 | 2008 |
Subcellular mRNA localization regulates ribosome biogenesis in migrating cells M Dermit, M Dodel, FCY Lee, MS Azman, H Schwenzer, JL Jones, ... Developmental cell 55 (3), 298-313. e10, 2020 | 68 | 2020 |
Spred2 interaction with the late endosomal protein NBR1 down-regulates fibroblast growth factor receptor signaling FK Mardakheh, M Yekezare, LM Machesky, JK Heath Journal of cell biology 187 (2), 265-277, 2009 | 56 | 2009 |
Nbr1 is a novel inhibitor of ligand-mediated receptor tyrosine kinase degradation FK Mardakheh, G Auciello, TR Dafforn, JZ Rappoport, JK Heath Molecular and cellular biology, 2010 | 52 | 2010 |
RHO binding to FAM65A regulates Golgi reorientation during cell migration FK Mardakheh, A Self, CJ Marshall Journal of cell science 129 (24), 4466-4479, 2016 | 51 | 2016 |
Methods for monitoring and measurement of protein translation in time and space M Dermit, M Dodel, FK Mardakheh Molecular BioSystems 13 (12), 2477-2488, 2017 | 48 | 2017 |
Centrosome amplification mediates small extracellular vesicle secretion via lysosome disruption SD Adams, J Csere, G D’angelo, EP Carter, M Romao, T Arnandis, ... Current Biology 31 (7), 1403-1416. e7, 2021 | 45 | 2021 |
A prometastatic splicing program regulated by SNRPA1 interactions with structured RNA elements L Fish, M Khoroshkin, A Navickas, K Garcia, B Culbertson, B Hänisch, ... Science 372 (6543), eabc7531, 2021 | 42 | 2021 |
Targeted online liquid chromatography electron capture dissociation mass spectrometry for the localization of sites of in vivo phosphorylation in human Sprouty2 SMM Sweet, FK Mardakheh, KJP Ryan, AJ Langton, JK Heath, HJ Cooper Analytical chemistry 80 (17), 6650-6657, 2008 | 41 | 2008 |
RBMS1 suppresses colon cancer metastasis through targeted stabilization of its mRNA regulon J Yu, A Navickas, H Asgharian, B Culbertson, L Fish, K Garcia, ... Cancer discovery 10 (9), 1410-1423, 2020 | 37 | 2020 |
DNA repair deficiency sensitizes lung cancer cells to NAD+ biosynthesis blockade M Touat, T Sourisseau, N Dorvault, RM Chabanon, M Garrido, D Morel, ... The Journal of Clinical Investigation 128 (4), 1671-1687, 2018 | 27 | 2018 |
Adipocytes disrupt the translational programme of acute lymphoblastic leukaemia to favour tumour survival and persistence Q Heydt, C Xintaropoulou, A Clear, M Austin, I Pislariu, F Miraki-Moud, ... Nature Communications 12 (1), 5507, 2021 | 19 | 2021 |
Maternal Larp6 controls oocyte development, chorion formation and elevation HTA Hau, O Ogundele, AH Hibbert, CAL Monfries, K Exelby, NJ Wood, ... Development 147 (4), dev187385, 2020 | 18 | 2020 |
The elongation factor eEF1A2 controls translation and actin dynamics in dendritic spines MB Mendoza, S Gutierrez, R Ortiz, DF Moreno, M Dermit, M Dodel, ... Science Signaling 14 (691), eabf5594, 2021 | 17 | 2021 |
A preclinical pipeline to evaluate migrastatics as therapeutic agents in metastatic melanoma O Maiques, B Fanshawe, E Crosas-Molist, I Rodriguez-Hernandez, ... British journal of cancer 125 (5), 699-713, 2021 | 16 | 2021 |
Proteomics profiling of interactome dynamics by colocalisation analysis (COLA) FK Mardakheh, HZ Sailem, S Kümper, CJ Tape, RR McCully, A Paul, ... Molecular BioSystems 13 (1), 92-105, 2017 | 16 | 2017 |