| The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling LAJ O'Neill, AG Bowie Nature Reviews Immunology 7 (5), 353-364, 2007 | 3399 | 2007 |
| The history of Toll-like receptors—redefining innate immunity LAJ O'neill, D Golenbock, AG Bowie Nature Reviews Immunology 13 (6), 453-460, 2013 | 2093 | 2013 |
| IFI16 is an innate immune sensor for intracellular DNA L Unterholzner, SE Keating, M Baran, KA Horan, SB Jensen, S Sharma, ... Nature immunology 11 (11), 997-1004, 2010 | 1806 | 2010 |
| Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction KA Fitzgerald, EM Palsson-McDermott, AG Bowie, CA Jefferies, ... Nature 413 (6851), 78-83, 2001 | 1686 | 2001 |
| Oxidative stress and nuclear factor-κB activation: a reassessment of the evidence in the light of recent discoveries A Bowie, LAJ O’Neill Biochemical pharmacology 59 (1), 13-23, 2000 | 1171 | 2000 |
| Viral evasion and subversion of pattern-recognition receptor signalling AG Bowie, L Unterholzner Nature Reviews Immunology 8 (12), 911-922, 2008 | 877 | 2008 |
| Immune sensing of DNA SR Paludan, AG Bowie Immunity 38 (5), 870-880, 2013 | 851 | 2013 |
| The interleukin‐1 receptor/Toll‐like receptor superfamily: signal generators for pro‐inflammatory interleukins and microbial products A Bowie, LAJ O'Neill Journal of leukocyte biology 67 (4), 508-514, 2000 | 776 | 2000 |
| The human adaptor SARM negatively regulates adaptor protein TRIF–dependent Toll-like receptor signaling M Carty, R Goodbody, M Schröder, J Stack, PN Moynagh, AG Bowie Nature immunology 7 (10), 1074-1081, 2006 | 697 | 2006 |
| The Toll–IL-1 receptor adaptor family grows to five members LAJ O'Neill, KA Fitzgerald, AG Bowie Trends in immunology 24 (6), 286-289, 2003 | 663 | 2003 |
| A46R and A52R from vaccinia virus are antagonists of host IL-1 and toll-like receptor signaling A Bowie, E Kiss-Toth, JA Symons, GL Smith, SK Dower, LAJ O'Neill Proceedings of the National Academy of Sciences 97 (18), 10162-10167, 2000 | 591 | 2000 |
| Structures of the HIN domain: DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor T Jin, A Perry, J Jiang, P Smith, JA Curry, L Unterholzner, Z Jiang, ... Immunity 36 (4), 561-571, 2012 | 583 | 2012 |
| The vaccine adjuvant chitosan promotes cellular immunity via DNA sensor cGAS-STING-dependent induction of type I interferons EC Carroll, L Jin, A Mori, N Munoz-Wolf, E Oleszycka, HBT Moran, ... Immunity 44 (3), 597-608, 2016 | 500 | 2016 |
| Non-canonical activation of the DNA sensing adaptor STING by ATM and IFI16 mediates NF-κB signaling after nuclear DNA damage G Dunphy, SM Flannery, JF Almine, DJ Connolly, C Paulus, KL Jønsson, ... Molecular cell 71 (5), 745-760. e5, 2018 | 495 | 2018 |
| The poxvirus protein A52R targets Toll-like receptor signaling complexes to suppress host defense MT Harte, IR Haga, G Maloney, P Gray, PC Reading, NW Bartlett, ... The Journal of experimental medicine 197 (3), 343-351, 2003 | 461 | 2003 |
| Vaccinia virus protein A46R targets multiple Toll-like–interleukin-1 receptor adaptors and contributes to virulence J Stack, IR Haga, M Schröder, NW Bartlett, G Maloney, PC Reading, ... The Journal of experimental medicine 201 (6), 1007-1018, 2005 | 448 | 2005 |
| Vitamin C inhibits NF-κB activation by TNF via the activation of p38 mitogen-activated protein kinase AG Bowie, LAJ O’Neill The Journal of Immunology 165 (12), 7180-7188, 2000 | 435 | 2000 |
| Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKε‐mediated IRF activation M Schröder, M Baran, AG Bowie The EMBO journal 27 (15), 2147-2157, 2008 | 431 | 2008 |
| Recognition of herpesviruses by the innate immune system SR Paludan, AG Bowie, KA Horan, KA Fitzgerald Nature Reviews Immunology 11 (2), 143-154, 2011 | 414 | 2011 |
| The interleukin-1 receptor-associated kinases: critical regulators of innate immune signalling S Flannery, AG Bowie Biochemical pharmacology 80 (12), 1981-1991, 2010 | 371 | 2010 |
Katherine FitzgeraldProfessor of Medicine, University of Massachusetts Medical SchoolVerified email at umassmed.edu
