Kelly SL
Kelly SL
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Functional profiling of the Saccharomyces cerevisiae genome
G Giaever, AM Chu, L Ni, C Connelly, L Riles, S Veronneau, S Dow, ...
nature 418 (6896), 387-391, 2002
Itraconazole resistance in Aspergillus fumigatus.
DW Denning, K Venkateswarlu, KL Oakley, MJ Anderson, NJ Manning, ...
Antimicrobial agents and chemotherapy 41 (6), 1364-1368, 1997
Molecular basis of resistance to azole antifungals
A Lupetti, R Danesi, M Campa, M Del Tacca, S Kelly
Trends in molecular medicine 8 (2), 76-81, 2002
Resistance to fluconazole and cross‐resistance to amphotericin B in Candida albicans from AIDS patients caused by defective sterol Δ5, 6‐desaturation
SL Kelly, DC Lamb, DE Kelly, NJ Manning, J Loeffler, H Hebart, ...
FEBS letters 400 (1), 80-82, 1997
Multiple molecular mechanisms contribute to a stepwise development of fluconazole resistance in clinical Candida albicans strains
R Franz, SL Kelly, DC Lamb, DE Kelly, M Ruhnke, J Morschhäuser
Antimicrobial agents and chemotherapy 42 (12), 3065-3072, 1998
Mode of action and resistance to azole antifungals associated with the formation of 14α-methylergosta-8, 24 (28)-dien-3β, 6α-diol
SL Kelly, DC Lamb, AJ Corran, BC Baldwin, DE Kelly
Biochemical and biophysical research communications 207 (3), 910-915, 1995
Azole fungicides–understanding resistance mechanisms in agricultural fungal pathogens
CL Price, JE Parker, AGS Warrilow, DE Kelly, SL Kelly
Pest management science 71 (8), 1054-1058, 2015
The mutation T315A in Candida albicans sterol 14α-demethylase causes reduced enzyme activity and fluconazole resistance through reduced affinity
DC Lamb, DE Kelly, WH Schunck, AZ Shyadehi, M Akhtar, DJ Lowe, ...
Journal of Biological Chemistry 272 (9), 5682-5688, 1997
Microbial cytochromes P450: biodiversity and biotechnology. Where do cytochromes P450 come from, what do they do and what can they do for us?
SL Kelly, DE Kelly
Phil. Trans. R. Soc. B 368 (1612), 20120476, 2013
Defective sterol C5-6 desaturation and azole resistance: a new hypothesis for the mode of action of azole antifungals
PF Watson, ME Rose, SW Ellis, H England, SL Kelly
Biochemical and biophysical research communications 164 (3), 1170-1175, 1989
The first virally encoded cytochrome p450
DC Lamb, L Lei, AGS Warrilow, GI Lepesheva, JGL Mullins, ...
Journal of virology 83 (16), 8266-8269, 2009
Biosynthesis of the sesquiterpene antibiotic albaflavenone in Streptomyces coelicolor A3 (2)
B Zhao, X Lin, L Lei, DC Lamb, SL Kelly, MR Waterman, DE Cane
Journal of Biological Chemistry 283 (13), 8183-8189, 2008
Molecular analysis of cyp51 from fluconazole‐resistant Candida albicans strains
J Löffler, SL Kelly, H Hebart, U Schumacher, C Lass‐Flörl, H Einsele
FEMS microbiology letters 151 (2), 263-268, 1997
Identification and characterization of four azole-resistant erg3 mutants of Candida albicans
CM Martel, JE Parker, O Bader, M Weig, U Gross, AGS Warrilow, N Rolley, ...
Antimicrobial agents and chemotherapy 54 (11), 4527-4533, 2010
Resistance to antifungals that target CYP51
JE Parker, AGS Warrilow, CL Price, JGL Mullins, DE Kelly, SL Kelly
Journal of Chemical Biology, 1-19, 2014
Systematic analysis of yeast strains with possible defects in lipid metabolism
G Daum, G Tuller, T Nemec, C Hrastnik, G Balliano, L Cattel, P Milla, ...
Yeast 15 (7), 601-614, 1999
A clinical isolate of Candida albicans with mutations in ERG11 (encoding sterol 14α-demethylase) and ERG5 (encoding C22 desaturase) is cross resistant to azoles and amphotericin B
CM Martel, JE Parker, O Bader, M Weig, U Gross, AGS Warrilow, DE Kelly, ...
Antimicrobial agents and chemotherapy 54 (9), 3578-3583, 2010
Binding of two flaviolin substrate molecules, oxidative coupling, and crystal structure of Streptomyces coelicolor A3 (2) cytochrome P450 158A2
B Zhao, FP Guengerich, A Bellamine, DC Lamb, M Izumikawa, L Lei, ...
Journal of Biological Chemistry 280 (12), 11599-11607, 2005
Characterization of the sterol 14α‐demethylases of Fusarium graminearum identifies a novel genus‐specific CYP51 function
J Fan, M Urban, JE Parker, HC Brewer, SL Kelly, KE Hammond‐Kosack, ...
New Phytologist 198 (3), 821-835, 2013
The R467K amino acid substitution in Candida albicans sterol 14α-demethylase causes drug resistance through reduced affinity
DC Lamb, DE Kelly, TC White, SL Kelly
Antimicrobial agents and chemotherapy 44 (1), 63-67, 2000
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