Aging and osteoarthritis: central role of the extracellular matrix M Rahmati, G Nalesso, A Mobasheri, M Mozafari Ageing research reviews 40, 20-30, 2017 | 422 | 2017 |
WNT-3A modulates articular chondrocyte phenotype by activating both canonical and noncanonical pathways G Nalesso, J Sherwood, J Bertrand, T Pap, M Ramachandran, C De Bari, ... Journal of Cell Biology 193 (3), 551-564, 2011 | 236 | 2011 |
WNT16 antagonises excessive canonical WNT activation and protects cartilage in osteoarthritis G Nalesso, BL Thomas, JC Sherwood, J Yu, O Addimanda, SE Eldridge, ... Annals of the rheumatic diseases 76 (1), 218-226, 2017 | 126 | 2017 |
A homeostatic function of CXCR2 signalling in articular cartilage J Sherwood, J Bertrand, G Nalesso, B Poulet, A Pitsillides, L Brandolini, ... Annals of the rheumatic diseases 74 (12), 2207-2215, 2015 | 78 | 2015 |
High density micromass cultures of a human chondrocyte cell line: a reliable assay system to reveal the modulatory functions of pharmacological agents KV Greco, AJ Iqbal, L Rattazzi, G Nalesso, N Moradi-Bidhendi, AR Moore, ... Biochemical pharmacology 82 (12), 1919-1929, 2011 | 73 | 2011 |
Agrin mediates chondrocyte homeostasis and requires both LRP4 and α-dystroglycan to enhance cartilage formation in vitro and in vivo S Eldridge, G Nalesso, H Ismail, K Vicente-Greco, P Kabouridis, ... Annals of the rheumatic diseases 75 (6), 1228-1235, 2016 | 58 | 2016 |
Culture expansion in low-glucose conditions preserves chondrocyte differentiation and enhances their subsequent capacity to form cartilage tissue in three-dimensional culture HK Heywood, G Nalesso, DA Lee, F Dell'Accio BioResearch open access 3 (1), 9-18, 2014 | 56 | 2014 |
Syndecan 4 supports bone fracture repair, but not fetal skeletal development, in mice J Bertrand, R Stange, H Hidding, F Echtermeyer, G Nalesso, L Godmann, ... Arthritis & Rheumatism 65 (3), 743-752, 2013 | 53 | 2013 |
ROR2 blockade as a therapy for osteoarthritis AS Thorup, D Strachan, S Caxaria, B Poulet, BL Thomas, SE Eldridge, ... Science translational medicine 12 (561), eaax3063, 2020 | 47 | 2020 |
Decreased levels of nucleotide pyrophosphatase phosphodiesterase 1 are associated with cartilage calcification in osteoarthritis and trigger osteoarthritic changes in mice J Bertrand, Y Nitschke, M Fuerst, S Hermann, M Schäfers, J Sherwood, ... Annals of the rheumatic diseases 71 (7), 1249-1253, 2012 | 36 | 2012 |
WNT3A‐loaded exosomes enable cartilage repair BL Thomas, SE Eldridge, B Nosrati, M Alvarez, AS Thorup, G Nalesso, ... Journal of extracellular vesicles 10 (7), e12088, 2021 | 31 | 2021 |
Cross-talk between PDGF and S1P signalling elucidates the inhibitory effect and potential antifibrotic action of the immunomodulator FTY720 in activated HSC-cultures AM Brunati, E Tibaldi, A Carraro, E Gringeri, F D’Amico Jr, A Toninello, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1783 (3), 347-359, 2008 | 31 | 2008 |
Extracellular genomic biomarkers of osteoarthritis E Budd, G Nalesso, A Mobasheri Expert review of molecular diagnostics 18 (1), 55-74, 2018 | 29 | 2018 |
Antagonism of human CC‐chemokine receptor 4 can be achieved through three distinct binding sites on the receptor RJ Slack, LJ Russell, NP Barton, C Weston, G Nalesso, SA Thompson, ... Pharmacology Research & Perspectives 1 (2), e00019, 2013 | 16 | 2013 |
Calcium calmodulin kinase II activity is required for cartilage homeostasis in osteoarthritis G Nalesso, AS Thorup, SE Eldridge, A De Palma, A Kaur, K Peddireddi, ... Scientific reports 11 (1), 5682, 2021 | 15 | 2021 |
Analyses on the mechanisms that underlie the chondroprotective properties of calcitonin KV Greco, G Nalesso, MK Kaneva, J Sherwood, AJ Iqbal, ... Biochemical Pharmacology 91 (3), 348-358, 2014 | 13 | 2014 |
WNT signalling in osteoarthritis and its pharmacological targeting A De Palma, G Nalesso Pharmacology of the WNT Signaling System, 337-356, 2021 | 9 | 2021 |
Hydroquinone exposure worsens rheumatoid arthritis through the activation of the aryl hydrocarbon receptor and interleukin-17 pathways CS Heluany, PB Donate, AH Schneider, AL Fabris, RA Gomes, ... Antioxidants 10 (6), 929, 2021 | 6 | 2021 |
Wnt signalling in the articular cartilage: A matter of balance AK Gill, PJ McCormick, D Sochart, G Nalesso International journal of experimental pathology 104 (2), 56-63, 2023 | 5 | 2023 |
Wnt5a/CaMKII pathway is activated in osteoarthritis and promotes loss of chondrocyte phenotype G Nalesso, BL Thomas, SE Eldridge, K Wagner, J Sherwood, J Bertrand, ... Osteoarthritis and Cartilage 21, S226, 2013 | 4 | 2013 |