| The amyloid state and its association with protein misfolding diseases TPJ Knowles, M Vendruscolo, CM Dobson Nature reviews Molecular cell biology 15 (6), 384-396, 2014 | 1620 | 2014 |
| Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism SIA Cohen, S Linse, LM Luheshi, E Hellstrand, DA White, L Rajah, ... Proceedings of the National Academy of Sciences 110 (24), 9758-9763, 2013 | 925 | 2013 |
| An analytical solution to the kinetics of breakable filament assembly TPJ Knowles, CA Waudby, GL Devlin, SIA Cohen, A Aguzzi, ... Science 326 (5959), 1533-1537, 2009 | 907 | 2009 |
| Role of intermolecular forces in defining material properties of protein nanofibrils TP Knowles, AW Fitzpatrick, S Meehan, HR Mott, M Vendruscolo, ... Science 318 (5858), 1900-1903, 2007 | 689 | 2007 |
| Nanomechanics of functional and pathological amyloid materials TPJ Knowles, MJ Buehler Nature nanotechnology 6 (8), 469-479, 2011 | 651 | 2011 |
| Direct observation of the interconversion of normal and toxic forms of α-synuclein N Cremades, SIA Cohen, E Deas, AY Abramov, AY Chen, A Orte, ... Cell 149 (5), 1048-1059, 2012 | 630 | 2012 |
| Characterization of the nanoscale properties of individual amyloid fibrils JF Smith, TPJ Knowles, CM Dobson, CE MacPhee, ME Welland Proceedings of the National Academy of Sciences 103 (43), 15806-15811, 2006 | 598 | 2006 |
| Atomic structure and hierarchical assembly of a cross-β amyloid fibril AWP Fitzpatrick, GT Debelouchina, MJ Bayro, DK Clare, MA Caporini, ... Proceedings of the National Academy of Sciences 110 (14), 5468-5473, 2013 | 448 | 2013 |
| On the lag phase in amyloid fibril formation P Arosio, TPJ Knowles, S Linse Physical Chemistry Chemical Physics 17 (12), 7606-7618, 2015 | 432 | 2015 |
| Solution conditions determine the relative importance of nucleation and growth processes in α-synuclein aggregation AK Buell, C Galvagnion, R Gaspar, E Sparr, M Vendruscolo, TPJ Knowles, ... Proceedings of the National Academy of Sciences 111 (21), 7671-7676, 2014 | 403 | 2014 |
| Metastability of native proteins and the phenomenon of amyloid formation AJ Baldwin, TPJ Knowles, GG Tartaglia, AW Fitzpatrick, GL Devlin, ... Journal of the American Chemical Society 133 (36), 14160-14163, 2011 | 376 | 2011 |
| From macroscopic measurements to microscopic mechanisms of protein aggregation SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles Journal of molecular biology 421 (2-3), 160-171, 2012 | 367 | 2012 |
| Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation C Galvagnion, AK Buell, G Meisl, TCT Michaels, M Vendruscolo, ... Nature chemical biology 11 (3), 229-234, 2015 | 359 | 2015 |
| Differences in nucleation behavior underlie the contrasting aggregation kinetics of the Aβ40 and Aβ42 peptides G Meisl, X Yang, E Hellstrand, B Frohm, JB Kirkegaard, SIA Cohen, ... Proceedings of the National Academy of Sciences 111 (26), 9384-9389, 2014 | 326 | 2014 |
| Nanostructured films from hierarchical self-assembly of amyloidogenic proteins TPJ Knowles, TW Oppenheim, AK Buell, DY Chirgadze, ME Welland Nature nanotechnology 5 (3), 204-207, 2010 | 324 | 2010 |
| Stabilization of neurotoxic Alzheimer amyloid-β oligomers by protein engineering A Sandberg, LM Luheshi, S Söllvander, TP de Barros, B Macao, ... Proceedings of the National Academy of Sciences 107 (35), 15595-15600, 2010 | 319 | 2010 |
| Molecular mechanisms of protein aggregation from global fitting of kinetic models G Meisl, JB Kirkegaard, P Arosio, TCT Michaels, M Vendruscolo, ... Nature protocols 11 (2), 252-272, 2016 | 312 | 2016 |
| Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formation SW Chen, S Drakulic, E Deas, M Ouberai, FA Aprile, R Arranz, S Ness, ... Proceedings of the National Academy of Sciences 112 (16), E1994-E2003, 2015 | 301 | 2015 |
| FUS phase separation is modulated by a molecular chaperone and methylation of arginine cation-π interactions S Qamar, GZ Wang, SJ Randle, FS Ruggeri, JA Varela, JQ Lin, ... Cell 173 (3), 720-734. e15, 2018 | 280 | 2018 |
| A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers SIA Cohen, P Arosio, J Presto, FR Kurudenkandy, H Biverstĺl, L Dolfe, ... Nature structural & molecular biology 22 (3), 207, 2015 | 276 | 2015 |
Christopher DobsonUniversity of CambridgeVerified email at cam.ac.uk
