Microglia emerge from erythromyeloid precursors via Pu. 1-and Irf8-dependent pathways K Kierdorf, D Erny, T Goldmann, V Sander, C Schulz, EG Perdiguero, ... Nature neuroscience 16 (3), 273-280, 2013 | 1642 | 2013 |
S100 proteins: structure, functions and pathology CW Heizmann, G Fritz, BW Schafer Front Biosci 7 (1), 1356-68, 2002 | 1177 | 2002 |
S100 proteins in mouse and man: from evolution to function and pathology (including an update of the nomenclature) I Marenholz, CW Heizmann, G Fritz Biochemical and biophysical research communications 322 (4), 1111-1122, 2004 | 1163 | 2004 |
A multimodal RAGE-specific inhibitor reduces amyloid β–mediated brain disorder in a mouse model of Alzheimer disease R Deane, I Singh, AP Sagare, RD Bell, NT Ross, B LaRue, R Love, ... The Journal of clinical investigation 122 (4), 1377-1392, 2012 | 698 | 2012 |
Binding of S100 proteins to RAGE: an update E Leclerc, G Fritz, SW Vetter, CW Heizmann Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1793 (6), 993-1007, 2009 | 607 | 2009 |
RAGE regulation and signaling in inflammation and beyond K Kierdorf, G Fritz Journal of leukocyte biology 94 (1), 55-68, 2013 | 503 | 2013 |
Molecular basis for manganese sequestration by calprotectin and roles in the innate immune response to invading bacterial pathogens SM Damo, TE Kehl-Fie, N Sugitani, ME Holt, S Rathi, WJ Murphy, ... Proceedings of the National Academy of Sciences 110 (10), 3841-3846, 2013 | 428 | 2013 |
RAGE: a single receptor fits multiple ligands G Fritz Trends in biochemical sciences 36 (12), 625-632, 2011 | 405 | 2011 |
S100B and S100A6 differentially modulate cell survival by interacting with distinct RAGE (receptor for advanced glycation end products) immunoglobulin domains E Leclerc, G Fritz, M Weibel, CW Heizmann, A Galichet Journal of Biological Chemistry 282 (43), 31317-31331, 2007 | 339 | 2007 |
Structural and functional insights into RAGE activation by multimeric S100B T Ostendorp, E Leclerc, A Galichet, M Koch, N Demling, B Weigle, ... The EMBO journal 26 (16), 3868-3878, 2007 | 324 | 2007 |
Structural basis for ligand recognition and activation of RAGE M Koch, S Chitayat, BM Dattilo, A Schiefner, J Diez, WJ Chazin, G Fritz Structure 18 (10), 1342-1352, 2010 | 291 | 2010 |
The extracellular region of the receptor for advanced glycation end products is composed of two independent structural units BM Dattilo, G Fritz, E Leclerc, CW Vander Kooi, CW Heizmann, ... Biochemistry 46 (23), 6957-6970, 2007 | 264 | 2007 |
USP 18 lack in microglia causes destructive interferonopathy of the mouse brain T Goldmann, N Zeller, J Raasch, K Kierdorf, K Frenzel, L Ketscher, ... The EMBO journal 34 (12), 1612-1629, 2015 | 207 | 2015 |
Cryo-EM structure of a transthyretin-derived amyloid fibril from a patient with hereditary ATTR amyloidosis M Schmidt, S Wiese, V Adak, J Engler, S Agarwal, G Fritz, P Westermark, ... Nature Communications 10 (1), 5008, 2019 | 175 | 2019 |
Mutations in POGLUT1, encoding protein O-glucosyltransferase 1, cause autosomal-dominant Dowling-Degos disease FB Basmanav, AM Oprisoreanu, SM Pasternack, H Thiele, G Fritz, ... The American Journal of Human Genetics 94 (1), 135-143, 2014 | 174 | 2014 |
The receptor for advanced glycation end-products (RAGE) is only present in mammals, and belongs to a family of cell adhesion molecules (CAMs) L Sessa, E Gatti, F Zeni, A Antonelli, A Catucci, M Koch, G Pompilio, ... PloS one 9 (1), e86903, 2014 | 169 | 2014 |
Cryo-EM structure of a light chain-derived amyloid fibril from a patient with systemic AL amyloidosis L Radamaker, YH Lin, K Annamalai, S Huhn, U Hegenbart, ... Nature communications 10 (1), 1103, 2019 | 166 | 2019 |
Natural and amyloid self‐assembly of S100 proteins: structural basis of functional diversity G Fritz, HM Botelho, LA Morozova‐Roche, CM Gomes The FEBS journal 277 (22), 4578-4590, 2010 | 165 | 2010 |
Structure of the V. cholerae Na+-pumping NADH:quinone oxidoreductase J Steuber, G Vohl, MS Casutt, T Vorburger, K Diederichs, G Fritz Nature 516 (7529), 62-67, 2014 | 134 | 2014 |
Structural basis of the specificity of USP18 toward ISG15 A Basters, PP Geurink, A Röcker, KF Witting, R Tadayon, S Hess, ... Nature structural & molecular biology 24 (3), 270-278, 2017 | 124 | 2017 |