| Amino acid and glucose metabolism in fed‐batch CHO cell culture affects antibody production and glycosylation Y Fan, I Jimenez Del Val, C Müller, J Wagtberg Sen, SK Rasmussen, ... Biotechnology and bioengineering 112 (3), 521-535, 2015 | 223 | 2015 |
| Towards the implementation of quality by design to the production of therapeutic monoclonal antibodies with desired glycosylation patterns IJ Del Val, C Kontoravdi, JM Nagy Biotechnology progress 26 (6), 1505-1527, 2010 | 181 | 2010 |
| Emerging technologies for low‐cost, rapid vaccine manufacture Z Kis, R Shattock, N Shah, C Kontoravdi Biotechnology journal 14 (1), 1800376, 2019 | 144 | 2019 |
| A dynamic mathematical model for monoclonal antibody N‐linked glycosylation and nucleotide sugar donor transport within a maturing Golgi apparatus I Jimenez del Val, JM Nagy, C Kontoravdi Biotechnology progress 27 (6), 1730-1743, 2011 | 140 | 2011 |
| Resources, production scales and time required for producing RNA vaccines for the global pandemic demand Z Kis, C Kontoravdi, R Shattock, N Shah Vaccines 9 (1), 3, 2020 | 132 | 2020 |
| How does mild hypothermia affect monoclonal antibody glycosylation? SN Sou, C Sellick, K Lee, A Mason, S Kyriakopoulos, KM Polizzi, ... Biotechnology and Bioengineering 112 (6), 1165-1176, 2015 | 121 | 2015 |
| ‘Closing the loop’in biological systems modeling—From the in silico to the in vitro A Kiparissides, M Koutinas, C Kontoravdi, A Mantalaris, EN Pistikopoulos Automatica 47 (6), 1147-1155, 2011 | 106 | 2011 |
| Application of global sensitivity analysis to determine goals for design of experiments: an example study on antibody‐producing cell cultures C Kontoravdi, SP Asprey, EN Pistikopoulos, A Mantalaris Biotechnology progress 21 (4), 1128-1135, 2005 | 101 | 2005 |
| The role of ER stress-induced apoptosis in neurodegeneration I C Stefani, D Wright, K M Polizzi, C Kontoravdi Current Alzheimer Research 9 (3), 373-387, 2012 | 93 | 2012 |
| Towards controlling the glycoform: a model framework linking extracellular metabolites to antibody glycosylation PM Jedrzejewski, IJ Del Val, A Constantinou, A Dell, SM Haslam, ... International journal of molecular sciences 15 (3), 4492-4522, 2014 | 92 | 2014 |
| Rapid development and deployment of high‐volume vaccines for pandemic response Z Kis, C Kontoravdi, AK Dey, R Shattock, N Shah Journal of advanced manufacturing and processing 2 (3), e10060, 2020 | 77 | 2020 |
| Systematic development of predictive mathematical models for animal cell cultures C Kontoravdi, EN Pistikopoulos, A Mantalaris Computers & Chemical Engineering 34 (8), 1192-1198, 2010 | 75 | 2010 |
| A multi‐pronged investigation into the effect of glucose starvation and culture duration on fed‐batch CHO cell culture Y Fan, I Jimenez Del Val, C Müller, AM Lund, JW Sen, SK Rasmussen, ... Biotechnology and bioengineering 112 (10), 2172-2184, 2015 | 69 | 2015 |
| Model‐based optimization of antibody galactosylation in CHO cell culture P Kotidis, P Jedrzejewski, SN Sou, C Sellick, K Polizzi, IJ Del Val, ... Biotechnology and bioengineering 116 (7), 1612-1626, 2019 | 63 | 2019 |
| Harnessing the potential of artificial neural networks for predicting protein glycosylation P Kotidis, C Kontoravdi Metabolic engineering communications 10, e00131, 2020 | 61 | 2020 |
| Genetically-encoded biosensors for monitoring cellular stress in bioprocessing KM Polizzi, C Kontoravdi Current opinion in biotechnology 31, 50-56, 2015 | 59 | 2015 |
| Development of a dynamic model of monoclonal antibody production and glycosylation for product quality monitoring C Kontoravdi, SP Asprey, EN Pistikopoulos, A Mantalaris Computers & chemical engineering 31 (5-6), 392-400, 2007 | 57 | 2007 |
| An optimized method for extraction and quantification of nucleotides and nucleotide sugars from mammalian cells IJ del Val, S Kyriakopoulos, KM Polizzi, C Kontoravdi Analytical biochemistry 443 (2), 172-180, 2013 | 56 | 2013 |
| In situ monitoring of intracellular glucose and glutamine in CHO cell culture A Behjousiar, C Kontoravdi, KM Polizzi PLoS One 7 (4), e34512, 2012 | 56 | 2012 |
| Host cell protein removal from biopharmaceutical preparations: Towards the implementation of quality by design CH Goey, S Alhuthali, C Kontoravdi Biotechnology advances 36 (4), 1223-1237, 2018 | 54 | 2018 |
Karen PolizziDepartment of Chemical Engineering, Imperial College LondonVerified email at imperial.ac.uk
