Iain Chalmers
Iain Chalmers
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Whole genome analysis of a schistosomiasis-transmitting freshwater snail
CM Adema, LDW Hillier, CS Jones, ES Loker, M Knight, P Minx, ...
Nature communications 8 (1), 15451, 2017
Anti-schistosomal intervention targets identified by lifecycle transcriptomic analyses
JM Fitzpatrick, E Peak, S Perally, IW Chalmers, J Barrett, TP Yoshino, ...
PLoS neglected tropical diseases 3 (11), e543, 2009
Developmentally regulated expression, alternative splicing and distinct sub-groupings in members of the Schistosoma mansoni venom allergen-like (SmVAL) gene …
IW Chalmers, AJ McArdle, RMR Coulson, MA Wagner, R Schmid, H Hirai, ...
BMC genomics 9, 1-20, 2008
Cytosine methylation regulates oviposition in the pathogenic blood fluke Schistosoma mansoni
KK Geyer, CM Rodríguez López, IW Chalmers, SE Munshi, M Truscott, ...
Nature communications 2 (1), 424, 2011
Development and Validation of a Quantitative, High-Throughput, Fluorescent-Based Bioassay to Detect Schistosoma Viability
E Peak, IW Chalmers, KF Hoffmann
PLoS neglected tropical diseases 4 (7), e759, 2010
Molecular characterization of omega-1: A hepatotoxic ribonuclease from Schistosoma mansonieggs
CM Fitzsimmons, G Schramm, FM Jones, IW Chalmers, KF Hoffmann, ...
Molecular & Biochemical Parasitology 144 (1), 123-127, 2005
The Schistosoma mansoni Tegumental-Allergen-Like (TAL) Protein Family: Influence of Developmental Expression on Human IgE Responses
CM Fitzsimmons, FM Jones, A Stearn, IW Chalmers, KF Hoffmann, ...
PLoS neglected tropical diseases 6 (4), e1593, 2012
The scandalous failure of scientists to cumulate scientifically
I Chalmers
Abstract to paper presented at: Ninth World Congress on Health Information …, 2005
Platyhelminth Venom Allergen-Like (VAL) proteins: revealing structural diversity, class-specific features and biological associations across the phylum
IW Chalmers, KF Hoffmann
Parasitology 139 (10), 1231-1245, 2012
The Biomphalaria glabrata DNA methylation machinery displays spatial tissue expression, is differentially active in distinct snail populations and is modulated by interactions …
KK Geyer, UH Niazi, D Duval, C Cosseau, C Tomlinson, IW Chalmers, ...
PLoS neglected tropical diseases 11 (5), e0005246, 2017
Excreted/secreted Schistosoma mansoni venom allergen-like 9 (SmVAL9) modulates host extracellular matrix remodelling gene expression
TP Yoshino, M Brown, XJ Wu, CJ Jackson, R Ocadiz-Ruiz, IW Chalmers, ...
International journal for parasitology 44 (8), 551-563, 2014
Cytosine methylation is a conserved epigenetic feature found throughout the phylum Platyhelminthes
KK Geyer, IW Chalmers, N MacKintosh, JE Hirst, R Geoghegan, M Badets, ...
BMC genomics 14, 1-13, 2013
Combining bioinformatics, cheminformatics, functional genomics and whole organism approaches for identifying epigenetic drug targets in Schistosoma mansoni
G Padalino, S Ferla, A Brancale, IW Chalmers, KF Hoffmann
International Journal for Parasitology: Drugs and Drug Resistance 8 (3), 559-570, 2018
Switching from originator to biosimilar infliximab in paediatric inflammatory bowel disease is feasible and uneventful
L Gervais, LL McLean, ML Wilson, C Cameron, L Curtis, V Garrick, ...
Journal of pediatric gastroenterology and nutrition 67 (6), 745-748, 2018
Drug-Induced Exposure of Schistosoma mansoni Antigens SmCD59a and SmKK7
N Reimers, A Homann, B Höschler, K Langhans, RA Wilson, C Pierrot, ...
PLOS Neglected Tropical Diseases 9 (3), e0003593, 2015
Schistosoma mansoni schistosomula antigens induce Th1/Pro‐inflammatory cytokine responses
M Egesa, L Lubyayi, EM Tukahebwa, BS Bagaya, IW Chalmers, S Wilson, ...
Parasite immunology 40 (12), e12592, 2018
The repositioning of epigenetic probes/inhibitors identifies new anti-schistosomal lead compounds and chemotherapeutic targets
KCL Whatley, G Padalino, H Whiteland, KK Geyer, BJ Hulme, ...
PLoS Neglected Tropical Diseases 13 (11), e0007693, 2019
Known Allergen Structures Predict Schistosoma mansoni IgE-Binding Antigens in Human Infection
EJ Farnell, N Tyagi, S Ryan, IW Chalmers, A Pinot de Moira, FM Jones, ...
Frontiers in immunology 6, 26, 2015
Schistosoma mansoni α-N-acetylgalactosaminidase (SmNAGAL) regulates coordinated parasite movement and egg production
BJ Hulme, KK Geyer, JE Forde-Thomas, G Padalino, DW Phillips, ...
PLoS pathogens 18 (1), e1009828, 2022
Schistosoma mansoni arginase shares functional similarities with human orthologs but depends upon disulphide bridges for enzymatic activity
JM Fitzpatrick, JM Fuentes, IW Chalmers, TA Wynn, M Modolell, ...
International journal for parasitology 39 (3), 267-279, 2009
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