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James Shayman
James Shayman
Professor of Internal Medicine
Verified email at umich.edu
Title
Cited by
Cited by
Year
Sphingolipids—the enigmatic lipid class: biochemistry, physiology, and pathophysiology
AH Merrill Jr, EM Schmelz, DL Dillehay, S Spiegel, JA Shayman, ...
Toxicology and applied pharmacology 142 (1), 208-225, 1997
8261997
Bcl-x and Bcl-2 inhibit TNF and Fas-induced apoptosis and activation of phospholipase A2 in breast carcinoma cells.
M Jäättelä, M Benedict, M Tewari, JA Shayman, VM Dixit
Oncogene 10 (12), 2297-2305, 1995
3941995
Increased alpha-adrenergic receptors in ischemic cat myocardium. A potential mediator of electrophysiological derangements.
PB Corr, JA Shayman, JB Kramer, RJ Kipnis
The Journal of Clinical Investigation 67 (4), 1232-1236, 1981
3221981
Improved inhibitors of glucosylceramide synthase
L Lee, A Abe, JA Shayman
Journal of Biological Chemistry 274 (21), 14662-14669, 1999
2991999
Globotriaosylceramide induces oxidative stress and up-regulates cell adhesion molecule expression in Fabry disease endothelial cells
JS Shen, XL Meng, DF Moore, JM Quirk, JA Shayman, R Schiffmann, ...
Molecular genetics and metabolism 95 (3), 163-168, 2008
2692008
(1S, 2R)-D-erythro-2-(N-Myristoylamino)-1-phenyl-1-propanol as an Inhibitor of Ceramidase (∗)
A Bielawska, MS Greenberg, D Perry, S Jayadev, JA Shayman, C McKay, ...
Journal of Biological Chemistry 271 (21), 12646-12654, 1996
2521996
Ganglioside-linked terminal sialic acid moieties on murine macrophages function as attachment receptors for murine noroviruses
S Taube, JW Perry, K Yetming, SP Patel, H Auble, L Shu, HF Nawar, ...
Journal of virology 83 (9), 4092-4101, 2009
2412009
Reduction of globotriaosylceramide in Fabry disease mice by substrate deprivation
A Abe, S Gregory, L Lee, PD Killen, RO Brady, A Kulkarni, JA Shayman
The Journal of clinical investigation 105 (11), 1563-1571, 2000
2362000
Structural and stereochemical studies of potent inhibitors of glucosylceramide synthase and tumor cell growth.
A Abe, NS Radin, JA Shayman, LL Wotring, RE Zipkin, R Sivakumar, ...
Journal of lipid research 36 (3), 611-621, 1995
2321995
Improved inhibitors of glucosylceramide synthase
A Abe, J Inokuchi, M Jimbo, H Shimeno, A Nagamatsu, JA Shayman, ...
The Journal of Biochemistry 111 (2), 191-196, 1992
2321992
Metabolic effects of inhibiting glucosylceramide synthesis with PDMP and other substances.
NS Radin
Adv. Lipid Res. 26, 183-213, 1993
2301993
Adipocyte ceramides regulate subcutaneous adipose browning, inflammation, and metabolism
B Chaurasia, VA Kaddai, GI Lancaster, DC Henstridge, S Sriram, ...
Cell metabolism 24 (6), 820-834, 2016
2162016
Inhibition of glucosylceramide accumulation results in effective blockade of polycystic kidney disease in mouse models
TA Natoli, LA Smith, KA Rogers, B Wang, S Komarnitsky, Y Budman, ...
Nature medicine 16 (7), 788-792, 2010
2032010
A specific and potent inhibitor of glucosylceramide synthase for substrate inhibition therapy of Gaucher disease
KA McEachern, J Fung, S Komarnitsky, CS Siegel, WL Chuang, E Hutto, ...
Molecular genetics and metabolism 91 (3), 259-267, 2007
1982007
Cell Cycle Arrest Induced by an Inhibitor of Glucosylceramide Synthase: CORRELATION WITH CYCLIN-DEPENDENT KINASES (∗)
SCS Rani, A Abe, Y Chang, N Rosenzweig, AR Saltiel, NS Radin, ...
Journal of Biological Chemistry 270 (6), 2859-2867, 1995
1901995
Modulation of renal epithelial cell growth by glucosylceramide. Association with protein kinase C, sphingosine, and diacylglycerol.
JA Shayman, GD Deshmukh, S Mahdiyoun, TP Thomas, D Wu, ...
Journal of Biological Chemistry 266 (34), 22968-22974, 1991
1581991
Ceramides and glucosylceramides are independent antagonists of insulin signaling
JA Chavez, MM Siddique, ST Wang, J Ching, JA Shayman, SA Summers
Journal of Biological Chemistry 289 (2), 723-734, 2014
1552014
Regulation of polymorphonuclear leukocyte phagocytosis by myosin light chain kinase after activation of mitogen-activated protein kinase
PJ Mansfield, JA Shayman, LA Boxer
Blood, The Journal of the American Society of Hematology 95 (7), 2407-2412, 2000
1532000
A role for glycosphingolipid accumulation in the renal hypertrophy of streptozotocin-induced diabetes mellitus.
IZ Zador, GD Deshmukh, R Kunkel, K Johnson, NS Radin, JA Shayman
The Journal of clinical investigation 91 (3), 797-803, 1993
1531993
Disruption of the glucosylceramide biosynthetic pathway in Aspergillus nidulans and Aspergillus fumigatus by inhibitors of UDP-Glc: ceramide glucosyltransferase strongly …
SB Levery, M Momany, R Lindsey, MS Toledo, JA Shayman, M Fuller, ...
FEBS letters 525 (1-3), 59-64, 2002
1522002
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