Derek Mann
Derek Mann
Professor of Hepatology, Newcastle University
Verified email at newcastle.ac.uk
Title
Cited by
Cited by
Year
The role and regulation of hepatic stellate cell apoptosis in reversal of liver fibrosis
AM Elsharkawy, F Oakley, DA Mann
Apoptosis 10 (5), 927-939, 2005
5482005
Chronic inflammation induces telomere dysfunction and accelerates ageing in mice
D Jurk, C Wilson, JF Passos, F Oakley, C Correia-Melo, L Greaves, ...
Nature communications 5 (1), 1-14, 2014
5272014
Gliotoxin stimulates the apoptosis of human and rat hepatic stellate cells and enhances the resolution of liver fibrosis in rats
MC Wright, R Issa, DE Smart, N Trim, GI Murray, JN Primrose, MJP Arthur, ...
Gastroenterology 121 (3), 685-698, 2001
4302001
Nuclear factor‐κB and the hepatic inflammation‐fibrosis‐cancer axis
AM Elsharkawy, DA Mann
Hepatology 46 (2), 590-597, 2007
4142007
Clinical evidence for the regression of liver fibrosis
EL Ellis, DA Mann
Journal of hepatology 56 (5), 1171-1180, 2012
3792012
Cellular senescence drives age-dependent hepatic steatosis
M Ogrodnik, S Miwa, T Tchkonia, D Tiniakos, CL Wilson, A Lahat, CP Day, ...
Nature communications 8 (1), 1-12, 2017
3642017
MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis
J Mann, DCK Chu, A Maxwell, F Oakley, NL Zhu, H Tsukamoto, DA Mann
Gastroenterology 138 (2), 705-714. e4, 2010
3552010
Mitochondria are required for pro‐ageing features of the senescent phenotype
C Correia‐Melo, FDM Marques, R Anderson, G Hewitt, R Hewitt, J Cole, ...
The EMBO journal 35 (7), 724-742, 2016
3412016
Inhibition of inhibitor of κB kinases stimulates hepatic stellate cell apoptosis and accelerated recovery from rat liver fibrosis
F Oakley, M Meso, JP Iredale, K Green, CJ Marek, X Zhou, MJ May, ...
Gastroenterology 128 (1), 108-120, 2005
3122005
Transcriptional regulation of hepatic stellate cell activation
DA Mann, DE Smart
Gut 50 (6), 891-896, 2002
2792002
Multigenerational epigenetic adaptation of the hepatic wound-healing response
M Zeybel, T Hardy, YK Wong, JC Mathers, CR Fox, A Gackowska, ...
Nature medicine 18 (9), 1369-1377, 2012
2562012
Regulation of myofibroblast transdifferentiation by DNA methylation and MeCP2: implications for wound healing and fibrogenesis
J Mann, F Oakley, F Akiboye, A Elsharkawy, AW Thorne, DA Mann
Cell Death & Differentiation 14 (2), 275-285, 2007
2442007
A molecular rheostat: Co-operative rev binding to stem I of the Rev-response element modulates human immunodeficiency virus type-1 late gene expression
DA Mann, I Mikaélian, RW Zemmel, SM Green, AD Lowe, T Kimura, ...
Journal of molecular biology 241 (2), 193-207, 1994
2381994
Neurite outgrowth in response to transfected N-CAM and N-cadherin reveals fundamental differences in neuronal responsiveness to CAMs
P Doherty, LH Rowett, SE Moore, DA Mann, FS Walsh
Neuron 6 (2), 247-258, 1991
2231991
A role for serotonin (5-HT) in hepatic stellate cell function and liver fibrosis
RG Ruddell, F Oakley, Z Hussain, I Yeung, LJ Bryan-Lluka, GA Ramm, ...
The American journal of pathology 169 (3), 861-876, 2006
1952006
Signal transduction via the NF‐κB pathway: a targeted treatment modality for infection, inflammation and repair
S Ali, DA Mann
Cell Biochemistry and Function: Cellular biochemistry and its modulation by …, 2004
1842004
Tissue inhibitors of metalloproteinases, hepatic stellate cells and liver fibrosis
MJP Arthur, DA Mann, JP Iredale
Journal of gastroenterology and hepatology 13 (S1), S33-S38, 1998
1841998
Identification of the Nef-associated kinase as p21-activated kinase 2
GH Renkema, A Manninen, DA Mann, M Harris, K Saksela
Current Biology 9 (23), 1407-1411, 1999
1811999
Stimulating healthy tissue regeneration by targeting the 5-HT 2B receptor in chronic liver disease
MR Ebrahimkhani, F Oakley, LB Murphy, J Mann, A Moles, MJ Perugorria, ...
Nature medicine 17 (12), 1668-1673, 2011
1792011
Persistent activation of nuclear factor‐κB in cultured rat hepatic stellate cells involves the induction of potentially novel rel‐like factors and prolonged changes in the …
AM Elsharkawy, MC Wright, RT Hay, MJ Arthur, T Hughes, MJ Bahr, ...
Hepatology 30 (3), 761-769, 1999
1711999
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