Vinay Varadan
Vinay Varadan
Executive Director, Computational Oncology and Immunology, Merck Research Laboratories
Verified email at
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Overcoming therapeutic resistance in HER2-positive breast cancers with CDK4/6 inhibitors
S Goel, Q Wang, AC Watt, SM Tolaney, DA Dillon, W Li, S Ramm, ...
Cancer cell 29 (3), 255-269, 2016
Association of peritumoral radiomics with tumor biology and pathologic response to preoperative targeted therapy for HER2 (ERBB2)–positive breast cancer
N Braman, P Prasanna, J Whitney, S Singh, N Beig, M Etesami, ...
JAMA network open 2 (4), e192561-e192561, 2019
Multi-cancer computational analysis reveals invasion-associated variant of desmoplastic reaction involving INHBA, THBS2 and COL11A1
H Kim, J Watkinson, V Varadan, D Anastassiou
BMC medical genomics 3, 1-11, 2010
Identification of tumor suppressors and oncogenes from genomic and epigenetic features in ovarian cancer
KO Wrzeszczynski, V Varadan, J Byrnes, E Lum, S Kamalakaran, ...
PloS one 6 (12), e28503, 2011
DNA methylation patterns in luminal breast cancers differ from non-luminal subtypes and can identify relapse risk independent of other clinical variables
S Kamalakaran, V Varadan, HEG Russnes, D Levy, J Kendall, A Janevski, ...
Molecular oncology 5 (1), 77-92, 2011
Novel recurrently mutated genes in African American colon cancers
K Guda, ML Veigl, V Varadan, A Nosrati, L Ravi, J Lutterbaugh, L Beard, ...
Proceedings of the National Academy of Sciences 112 (4), 1149-1154, 2015
ICAM1 initiates CTC cluster formation and trans-endothelial migration in lung metastasis of breast cancer
R Taftaf, X Liu, S Singh, Y Jia, NK Dashzeveg, AD Hoffmann, ...
Nature communications 12 (1), 4867, 2021
Interferon-beta represses cancer stem cell properties in triple-negative breast cancer
MR Doherty, HJ Cheon, DJ Junk, S Vinayak, V Varadan, ML Telli, JM Ford, ...
Proceedings of the National Academy of Sciences 114 (52), 13792-13797, 2017
Radiogenomic analysis of hypoxia pathway is predictive of overall survival in Glioblastoma
N Beig, J Patel, P Prasanna, V Hill, A Gupta, R Correa, K Bera, S Singh, ...
Scientific reports 8 (1), 7, 2018
Immune signatures following single dose trastuzumab predict pathologic response to preoperativetrastuzumab and chemotherapy in HER2-positive early breast cancer
V Varadan, H Gilmore, KLS Miskimen, D Tuck, S Parsai, A Awadallah, ...
Clinical Cancer Research 22 (13), 3249-3259, 2016
Computational inference of the molecular logic for synaptic connectivity in C. elegans
V Varadan, DM Miller III, D Anastassiou
Bioinformatics 22 (14), e497-e506, 2006
Radiogenomic-based survival risk stratification of tumor habitat on Gd-T1w MRI is associated with biological processes in glioblastoma
N Beig, K Bera, P Prasanna, J Antunes, R Correa, S Singh, ...
Clinical Cancer Research 26 (8), 1866-1876, 2020
Classification of audio radar signals using radial basis function neural networks
T McConaghy, H Leung, E Bosse, V Varadan
IEEE Transactions on Instrumentation and Measurement 52 (6), 1771-1779, 2003
Novel insights into breast cancer copy number genetic heterogeneity revealed by single-cell genome sequencing
T Baslan, J Kendall, K Volyanskyy, K McNamara, H Cox, S D'Italia, ...
elife 9, e51480, 2020
Variable window binding for mutually exclusive alternative splicing
D Anastassiou, H Liu, V Varadan
Genome biology 7, 1-12, 2006
Translating next generation sequencing to practice: opportunities and necessary steps
S Kamalakaran, V Varadan, A Janevski, N Banerjee, D Tuck, ...
Molecular Oncology 7 (4), 743-755, 2013
Secure communication using a chaos based signal encryption scheme
K Murali, H Yu, V Varadan, H Leung
IEEE Transactions on Consumer Electronics 47 (4), 709-714, 2001
Biochemical and functional characterization of glycosylation-associated mutational landscapes in colon cancer
S Venkitachalam, L Revoredo, V Varadan, RE Fecteau, L Ravi, ...
Scientific reports 6 (1), 23642, 2016
Systems biology analyses show hyperactivation of transforming growth factor-β and JNK signaling pathways in esophageal cancer
AE Blum, S Venkitachalam, D Ravillah, AK Chelluboyina, ...
Gastroenterology 156 (6), 1761-1774, 2019
Inference of disease-related molecular logic from systems-based microarray analysis
V Varadan, D Anastassiou
PLoS computational biology 2 (6), e68, 2006
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