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Robert B Good
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Endothelial to mesenchymal transition contributes to endothelial dysfunction in pulmonary arterial hypertension
RB Good, AJ Gilbane, SL Trinder, CP Denton, G Coghlan, DJ Abraham, ...
The American journal of pathology 185 (7), 1850-1858, 2015
3182015
A novel murine model of severe pulmonary arterial hypertension
L Ciuclan, O Bonneau, M Hussey, N Duggan, AM Holmes, R Good, ...
American journal of respiratory and critical care medicine 184 (10), 1171-1182, 2011
2962011
The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis
HV Woodcock, JD Eley, D Guillotin, M Platé, CB Nanthakumar, M Martufi, ...
Nature communications 10 (1), 1-16, 2019
1602019
Imatinib attenuates hypoxia-induced pulmonary arterial hypertension pathology via reduction in 5-hydroxytryptamine through inhibition of tryptophan hydroxylase 1 expression
L Ciuclan, MJ Hussey, V Burton, R Good, N Duggan, S Beach, P Jones, ...
American journal of respiratory and critical care medicine 187 (1), 78-89, 2013
802013
Impaired bone morphogenetic protein receptor II signaling in a transforming growth factor-β–dependent mouse model of pulmonary hypertension and in systemic sclerosis
AJ Gilbane, E Derrett-Smith, SL Trinder, RB Good, A Pearce, CP Denton, ...
American journal of respiratory and critical care medicine 191 (6), 665-677, 2015
662015
Loss of functional BAP1 augments sensitivity to TRAIL in cancer cells
KK Kolluri, C Alifrangis, N Kumar, Y Ishii, S Price, M Michaut, S Williams, ...
Elife 7, e30224, 2018
342018
Prolonged Scar-in-a-Jar: an in vitro screening tool for anti-fibrotic therapies using biomarkers of extracellular matrix synthesis
SR Rønnow, RQ Dabbagh, F Genovese, CB Nanthakumar, VJ Barrett, ...
Respiratory Research 21 (1), 1-14, 2020
312020
Single-Step, High-Efficiency CRISPR-Cas9 Genome Editing in Primary Human Disease-Derived Fibroblasts
M Martufi, RB Good, R Rapiteanu, T Schmidt, E Patili, K Tvermosegaard, ...
The CRISPR journal 2 (1), 31-40, 2019
292019
A high content, phenotypic ‘scar-in-a-jar’assay for rapid quantification of collagen fibrillogenesis using disease-derived pulmonary fibroblasts
RB Good, JD Eley, E Gower, G Butt, AD Blanchard, AJ Fisher, ...
BMC Biomedical Engineering 1 (1), 14, 2019
192019
Decellularized Human Liver as a Natural 3D Scaffold for Organ Engineering and 3D-Disease Modeling
G Mazza, K Rombouts, AR Hall, L Urbani, L Longato, AM Holmes, ...
Hepatology 60, 243A-243A, 2014
12014
Imatinib attenuates hypoxia-induced PAH pathology via reduction in serotonin through inhibition of tryptophan hydroxylase 1 expression
LI Ciuclan, M Hussey, N Duggan, VJ Burton, R Good, S Beach, P Jones, ...
A29. PATHOGENESIS OF PULMONARY HYPERTENSION, A1242-A1242, 2012
12012
Endothelial dysfunction in the development of vascular complications in Systemic Sclerosis
RBW Good
UCL (University College London), 2016
2016
Bromodomain Inhibitor JQ1 Modulates Smooth Muscle Cell Switching and Ameliorates Chronic Hypoxia/SU5416-Induced Pulmonary Arterial Hypertension in Mice
SL Trinder, A Gilbane, R Good, EC Derrett-Smith, CP Denton, D Abraham, ...
Arthritis & Rheumatology 67, 2015
2015
Blood Outgrowth Endothelial Cells Isolated from Systemic Sclerosis Patients Exhibit a Pro-Inflammatory Phenotype
R Good, S Trinder, C Denton, D Abraham, A Holmes
2015 ACR/ARHP Annual Meeting Abstracts, 2015
2015
Endothelial to Mesenchymal Transition Contributes to the Development of Pulmonary Vasculopathy in Systemic Sclerosis PAH.: 1717
R Good, A Gilbane, S Trinder, D Abraham, C Denton, A Holmes
Arthritis & Rheumatology 66, 2014
2014
The role of MCSF and endothelin 1 in fibrocyte differentiation
S Trinder, X Shi-wen, B Ahmed-Abdi, R Good, A Gilbane, C Denton, ...
Clinical and Experimental Rheumatology 32 (2), S59-S60, 2014
2014
Characterisation of late-outgrowth endothelial progenitor cells from systemic sclerosis patients
R Good, S Trinder, S Abdi, R Yu, C Denton, D Abraham, A Holmes
Clinical and Experimental Rheumatology 32 (2), S32-S33, 2014
2014
Endothelial to Mesenchymal Transition (EndoMT) leads to a loss of normal endothelial cell function and may contribute to the development of pulmonary arterial hypertension
R Good, A Gilbane, S Trinder, C Denton, G Coghlan, D Abraham, ...
Molecular Biology of the Cell 25, 2014
2014
Reduction in serotonin signaling via TPH1 inhibition attenuates the progression of PAH in mice with genetic ablation of endothelial BMPR-II
L Ciuclan, N Duggan, M Hussey, R Good, O Bonneau, D Rowlands, ...
European Respiratory Journal 40 (Suppl 56), 4554, 2012
2012
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Articles 1–19