Endothelial to mesenchymal transition contributes to endothelial dysfunction in pulmonary arterial hypertension RB Good, AJ Gilbane, SL Trinder, CP Denton, G Coghlan, DJ Abraham, ... The American journal of pathology 185 (7), 1850-1858, 2015 | 318 | 2015 |
A novel murine model of severe pulmonary arterial hypertension L Ciuclan, O Bonneau, M Hussey, N Duggan, AM Holmes, R Good, ... American journal of respiratory and critical care medicine 184 (10), 1171-1182, 2011 | 296 | 2011 |
The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis HV Woodcock, JD Eley, D Guillotin, M Platé, CB Nanthakumar, M Martufi, ... Nature communications 10 (1), 1-16, 2019 | 160 | 2019 |
Imatinib attenuates hypoxia-induced pulmonary arterial hypertension pathology via reduction in 5-hydroxytryptamine through inhibition of tryptophan hydroxylase 1 expression L Ciuclan, MJ Hussey, V Burton, R Good, N Duggan, S Beach, P Jones, ... American journal of respiratory and critical care medicine 187 (1), 78-89, 2013 | 80 | 2013 |
Impaired bone morphogenetic protein receptor II signaling in a transforming growth factor-β–dependent mouse model of pulmonary hypertension and in systemic sclerosis AJ Gilbane, E Derrett-Smith, SL Trinder, RB Good, A Pearce, CP Denton, ... American journal of respiratory and critical care medicine 191 (6), 665-677, 2015 | 66 | 2015 |
Loss of functional BAP1 augments sensitivity to TRAIL in cancer cells KK Kolluri, C Alifrangis, N Kumar, Y Ishii, S Price, M Michaut, S Williams, ... Elife 7, e30224, 2018 | 34 | 2018 |
Prolonged Scar-in-a-Jar: an in vitro screening tool for anti-fibrotic therapies using biomarkers of extracellular matrix synthesis SR Rønnow, RQ Dabbagh, F Genovese, CB Nanthakumar, VJ Barrett, ... Respiratory Research 21 (1), 1-14, 2020 | 31 | 2020 |
Single-Step, High-Efficiency CRISPR-Cas9 Genome Editing in Primary Human Disease-Derived Fibroblasts M Martufi, RB Good, R Rapiteanu, T Schmidt, E Patili, K Tvermosegaard, ... The CRISPR journal 2 (1), 31-40, 2019 | 29 | 2019 |
A high content, phenotypic ‘scar-in-a-jar’assay for rapid quantification of collagen fibrillogenesis using disease-derived pulmonary fibroblasts RB Good, JD Eley, E Gower, G Butt, AD Blanchard, AJ Fisher, ... BMC Biomedical Engineering 1 (1), 14, 2019 | 19 | 2019 |
Decellularized Human Liver as a Natural 3D Scaffold for Organ Engineering and 3D-Disease Modeling G Mazza, K Rombouts, AR Hall, L Urbani, L Longato, AM Holmes, ... Hepatology 60, 243A-243A, 2014 | 1 | 2014 |
Imatinib attenuates hypoxia-induced PAH pathology via reduction in serotonin through inhibition of tryptophan hydroxylase 1 expression LI Ciuclan, M Hussey, N Duggan, VJ Burton, R Good, S Beach, P Jones, ... A29. PATHOGENESIS OF PULMONARY HYPERTENSION, A1242-A1242, 2012 | 1 | 2012 |
Endothelial dysfunction in the development of vascular complications in Systemic Sclerosis RBW Good UCL (University College London), 2016 | | 2016 |
Bromodomain Inhibitor JQ1 Modulates Smooth Muscle Cell Switching and Ameliorates Chronic Hypoxia/SU5416-Induced Pulmonary Arterial Hypertension in Mice SL Trinder, A Gilbane, R Good, EC Derrett-Smith, CP Denton, D Abraham, ... Arthritis & Rheumatology 67, 2015 | | 2015 |
Blood Outgrowth Endothelial Cells Isolated from Systemic Sclerosis Patients Exhibit a Pro-Inflammatory Phenotype R Good, S Trinder, C Denton, D Abraham, A Holmes 2015 ACR/ARHP Annual Meeting Abstracts, 2015 | | 2015 |
Endothelial to Mesenchymal Transition Contributes to the Development of Pulmonary Vasculopathy in Systemic Sclerosis PAH.: 1717 R Good, A Gilbane, S Trinder, D Abraham, C Denton, A Holmes Arthritis & Rheumatology 66, 2014 | | 2014 |
The role of MCSF and endothelin 1 in fibrocyte differentiation S Trinder, X Shi-wen, B Ahmed-Abdi, R Good, A Gilbane, C Denton, ... Clinical and Experimental Rheumatology 32 (2), S59-S60, 2014 | | 2014 |
Characterisation of late-outgrowth endothelial progenitor cells from systemic sclerosis patients R Good, S Trinder, S Abdi, R Yu, C Denton, D Abraham, A Holmes Clinical and Experimental Rheumatology 32 (2), S32-S33, 2014 | | 2014 |
Endothelial to Mesenchymal Transition (EndoMT) leads to a loss of normal endothelial cell function and may contribute to the development of pulmonary arterial hypertension R Good, A Gilbane, S Trinder, C Denton, G Coghlan, D Abraham, ... Molecular Biology of the Cell 25, 2014 | | 2014 |
Reduction in serotonin signaling via TPH1 inhibition attenuates the progression of PAH in mice with genetic ablation of endothelial BMPR-II L Ciuclan, N Duggan, M Hussey, R Good, O Bonneau, D Rowlands, ... European Respiratory Journal 40 (Suppl 56), 4554, 2012 | | 2012 |