| Lactate-mediated epigenetic reprogramming regulates formation of human pancreatic cancer-associated fibroblasts TD Bhagat, D Von Ahrens, M Dawlaty, Y Zou, J Baddour, A Achreja, ... Elife 8, e50663, 2019 | 116 | 2019 |
| The proton-coupled folate transporter (PCFT-SLC46A1) and the syndrome of systemic and cerebral folate deficiency of infancy: hereditary folate malabsorption R Zhao, S Aluri, ID Goldman Molecular aspects of medicine 53, 57-72, 2017 | 65 | 2017 |
| One-carbon metabolic pathway rewiring in Escherichia coli reveals an evolutionary advantage of 10-formyltetrahydrofolate synthetase (Fhs) in survival under hypoxia S Sah, S Aluri, K Rex, U Varshney Journal of bacteriology 197 (4), 717-726, 2015 | 47 | 2015 |
| Biological basis for efficacy of activin receptor ligand traps in myelodysplastic syndromes A Verma, RNVS Suragani, S Aluri, N Shah, TD Bhagat, MJ Alexander, ... The Journal of Clinical Investigation 130 (2), 582-589, 2020 | 44 | 2020 |
| Functional succinate dehydrogenase deficiency is a common adverse feature of clear cell renal cancer RK Aggarwal, RA Luchtel, V Machha, A Tischer, Y Zou, K Pradhan, ... Proceedings of the National Academy of Sciences 118 (39), e2106947118, 2021 | 34 | 2021 |
| Activation of targetable inflammatory immune signaling is seen in myelodysplastic syndromes with SF3B1 mutations GS Choudhary, A Pellagatti, B Agianian, MA Smith, TD Bhagat, ... Elife 11, e78136, 2022 | 28 | 2022 |
| High burden of clonal hematopoiesis in first responders exposed to the World Trade Center disaster S Jasra, O Giricz, R Zeig-Owens, K Pradhan, DG Goldfarb, ... Nature medicine 28 (3), 468-471, 2022 | 25 | 2022 |
| Hereditary folate malabsorption due to a mutation in the external gate of the proton-coupled folate transporter SLC46A1 S Aluri, R Zhao, C Lubout, SMI Goorden, A Fiser, ID Goldman Blood Advances 2 (1), 61-68, 2018 | 22 | 2018 |
| Stem cell mutations can be detected in myeloma patients years before onset of secondary leukemias A Sridharan, CD Schinke, G Georgiev, M Da Silva Ferreira, ... Blood advances 3 (23), 3962-3967, 2019 | 15 | 2019 |
| Methylation of dual-specificity phosphatase 4 controls cell differentiation H Su, M Jiang, C Senevirathne, S Aluri, T Zhang, H Guo, J Xavier-Ferrucio, ... Cell reports 36 (4), 2021 | 14 | 2021 |
| SF3B1 mutations induce oncogenic IRAK4 isoforms and activate targetable innate immune pathways in MDS and AML GS Choudhary, MA Smith, A Pellagatti, TD Bhagat, S Gordon, S Pandey, ... Blood 134, 4224, 2019 | 13 | 2019 |
| Residues in the eighth transmembrane domain of the proton-coupled folate transporter (SLC46A1) play an important role in defining the aqueous translocation pathway and in … S Aluri, R Zhao, A Fiser, ID Goldman Biochimica et Biophysica Acta (BBA)-Biomembranes 1859 (11), 2193-2202, 2017 | 11 | 2017 |
| Innate immune mediator, Interleukin-1 receptor accessory protein (IL1RAP), is expressed and pro-tumorigenic in pancreatic cancer Y Zhang, X Chen, H Wang, S Gordon-Mitchell, S Sahu, TD Bhagat, ... Journal of Hematology & Oncology 15 (1), 70, 2022 | 9 | 2022 |
| Substitutions that lock and unlock the proton-coupled folate transporter (PCFT-SLC46A1) in an inward-open conformation S Aluri, R Zhao, K Lin, DS Shin, A Fiser, ID Goldman Journal of Biological Chemistry 294 (18), 7245-7258, 2019 | 9 | 2019 |
| Fidelity of translation in the presence of mammalian mitochondrial initiation factor 3 SA Ayyub, SL Aswathy, D Dobriyal, S Aluri, LL Spremulli, U Varshney Mitochondrion 39, 1-8, 2018 | 8 | 2018 |
| Impact of posttranslational modifications of engineered cysteines on the substituted cysteine accessibility method: evidence for glutathionylation R Zhao, M Najmi, S Aluri, ID Goldman American Journal of Physiology-Cell Physiology 312 (4), C517-C526, 2017 | 8 | 2017 |
| A proton-coupled folate transporter mutation causing hereditary folate malabsorption locks the protein in an inward-open conformation HQ Zhan, M Najmi, K Lin, S Aluri, A Fiser, ID Goldman, R Zhao Journal of Biological Chemistry 295 (46), 15650-15661, 2020 | 6 | 2020 |
| Rewiring of one carbon metabolism in Salmonella serves as an excellent live vaccine against systemic salmonellosis A Datey, M Shreenivas, G Chandrasekharan, J Joseph, S Sah, S Aluri, ... Vaccine 36 (50), 7715-7727, 2018 | 6 | 2018 |
| Concentrative transport of antifolates mediated by the proton-coupled folate transporter (SLC46A1); augmentation by a HEPES buffer R Zhao, M Najmi, S Aluri, DC Spray, ID Goldman Molecular pharmacology 93 (3), 208-215, 2018 | 6 | 2018 |
| Substituted-cysteine accessibility and cross-linking identify an exofacial cleft in the 7th and 8th helices of the proton-coupled folate transporter (SLC46A1) S Aluri, R Zhao, A Fiser, ID Goldman American Journal of Physiology-Cell Physiology 314 (3), C289-C296, 2018 | 6 | 2018 |
Umesh VarshneyIndian Institute of ScienceVerified email at iisc.ac.in
