|Cross sectional evaluation of the gut-microbiome metabolome axis in an Italian cohort of IBD patients|
ML Santoru, C Piras, A Murgia, V Palmas, T Camboni, S Liggi, I Ibba, ...
Scientific reports 7 (1), 9523, 2017
|Anti-cancer drug development: Computational strategies to identify and target proteins involved in cancer metabolism|
L Mak, S Liggi, L Tan, K Kusonmano, J M Rollinger, A Koutsoukas, ...
Current pharmaceutical design 19 (4), 532-577, 2013
|The potential of Ion Mobility Mass Spectrometry for high-throughput and high-resolution lipidomics|
C Hinz, S Liggi, JL Griffin
Current Opinion in Chemical Biology 42, 42-50, 2018
|Connecting gene expression data from connectivity map and in silico target predictions for small molecule mechanism-of-action analysis|
AC Ravindranath, N Perualila-Tan, A Kasim, G Drakakis, S Liggi, ...
Molecular BioSystems, 2014
|Extensions to In Silico Bioactivity Predictions Using Pathway Annotations and Differential Pharmacology Analysis: Application to Xenopus laevis Phenotypic Readouts|
S Liggi, G Drakakis, AE Hendry, KM Hanson, SC Brewerton, GN Wheeler, ...
Molecular Informatics 32 (11‐12), 1009-1024, 2013
|Extending in silico mechanism-of-action analysis by annotating targets with pathways: application to cellular cytotoxicity readouts|
S Liggi, G Drakakis, A Koutsoukas, I Cortes-Ciriano, P Martínez-Alonso, ...
Future Medicinal Chemistry 6 (18), 2029-2056, 2014
|Metabolomic analysis identifies altered metabolic pathways in multiple Sclerosis|
S Poddighe, F Murgia, L Lorefice, S Liggi, E Cocco, MG Marrosu, L Atzori
The international journal of biochemistry & cell biology 93, 148-155, 2017
|KniMet: a pipeline for the processing of chromatography–mass spectrometry metabolomics data|
S Liggi, C Hinz, Z Hall, ML Santoru, S Poddighe, J Fjeldsted, L Atzori, ...
Metabolomics 14 (4), 52, 2018
|Global Mapping of Traditional Chinese Medicine into Bioactivity Space and Pathways Annotation Improves Mechanistic Understanding and Discovers Relationships between Therapeutic …|
SZ Mohamad Zobir, F Mohd Fauzi, S Liggi, G Drakakis, X Fu, TP Fan, ...
Evidence-Based Complementary and Alternative Medicine 2016, 2016
|Metabolomics applied to diabetes− lessons from human population studies|
S Liggi, JL Griffin
The international journal of biochemistry & cell biology 93, 136-147, 2017
|Using Molecular Initiating Events To Generate 2D Structure–Activity Relationships for Toxicity Screening|
TEH Allen, S Liggi, JM Goodman, S Gutsell, PJ Russell
Chemical Research in Toxicology 29 (10), 1611-1627, 2016
|Metabolomic profile in hyperthyroid patients before and after antithyroid drug treatment: Correlation with thyroid hormone and TSH concentration|
C Piras, N Arisci, S Poddighe, S Liggi, S Mariotti, L Atzori
The international journal of biochemistry & cell biology 93, 119-128, 2017
|Base sequence specificity of counterion binding to DNA: what can MD simulations tell us?|
A Atzori, S Liggi, A Laaksonen, M Porcu, AP Lyubartsev, G Saba, F Mocci
Canadian Journal of Chemistry 94 (12), 1181-1188, 2016
|Italian cohort of patients affected by inflammatory bowel disease is characterised by variation in glycerophospholipid, free fatty acids and amino acid levels|
A Murgia, C Hinz, S Liggi, J Denes, Z Hall, J West, ML Santoru, C Piras, ...
Metabolomics 14 (10), 140, 2018
|A comprehensive UHPLC ion mobility QTOF method for profiling and quantification of eicosanoids, other oxylipins and fatty acids.|
C Hinz, S Liggi, G Mocciaro, SM Jung, I Induruwa, MCDA Pereira, ...
Analytical chemistry, 2019
|Crosstalk between Metabolic Alterations and Altered Redox Balance in PTC-Derived Cell Lines|
L Tronci, P Caria, DV Frau, S Liggi, C Piras, F Murgia, ML Santoru, ...
Metabolites 9 (2), 23, 2019
|Annotating targets with pathways: extending approaches to mode of action analysis|
S Liggi, A Koutsoukas, YK Motamedi, RC Glen, A Bender
Journal of Cheminformatics 5 (Suppl 1), P15, 2013
|Molecular Dynamics Investigations on Base Sequence Specificity of Counterion Binding to DNA|
A Atzori, S Liggi, A Laaksonen, A Lyubartsev, G Saba, M Porcu, F Mocci
Biophysical Journal 102 (3), 637a, 2012
|High protein feeding induces de novo lipogenesis in healthy humans: a randomised 3-way crossover study|
E Charidemou, T Ashmore, X Li, BD McNally, JA West, S Liggi, M Harvey, ...
JCI Insight, 2019
|The consequences of lipid remodelling of adipocyte cell membranes being functionally distinct from global lipid storage during obesity|
A Acharjee, C Hinz, S Liggi, A Murgia, J Denes, MK Gulston, X Wang, ...
bioRxiv, 712976, 2019