CBP30, a selective CBP/p300 bromodomain inhibitor, suppresses human Th17 responses A Hammitzsch, C Tallant, O Fedorov, A O’Mahony, PE Brennan, DA Hay, ... Proceedings of the National Academy of Sciences 112 (34), 10768-10773, 2015 | 252 | 2015 |
Peripheral CD8+ T cell characteristics associated with durable responses to immune checkpoint blockade in patients with metastatic melanoma BP Fairfax, CA Taylor, RA Watson, I Nassiri, S Danielli, H Fang, EA Mahé, ... Nature medicine 26 (2), 193-199, 2020 | 246 | 2020 |
Progress in our understanding of the pathogenesis of ankylosing spondylitis D Simone, MH Al Mossawi, P Bowness Rheumatology 57 (suppl_6), vi4-vi9, 2018 | 132 | 2018 |
Unique transcriptome signatures and GM-CSF expression in lymphocytes from patients with spondyloarthritis MH Al-Mossawi, L Chen, H Fang, A Ridley, J De Wit, N Yager, ... Nature communications 8 (1), 1510, 2017 | 129 | 2017 |
Single-cell sequencing reveals clonal expansions of pro-inflammatory synovial CD8 T cells expressing tissue-homing receptors in psoriatic arthritis F Penkava, MDC Velasco-Herrera, MD Young, N Yager, LN Nwosu, ... Nature communications 11 (1), 4767, 2020 | 121 | 2020 |
Multi-omic single cell analysis resolves novel stromal cell populations in healthy and diseased human tendon AR Kendal, T Layton, H Al-Mossawi, L Appleton, S Dakin, R Brown, ... Scientific reports 10 (1), 13939, 2020 | 83 | 2020 |
Silencing or inhibition of endoplasmic reticulum aminopeptidase 1 (ERAP1) suppresses free heavy chain expression and Th17 responses in ankylosing spondylitis L Chen, A Ridley, A Hammitzsch, MH Al-Mossawi, H Bunting, ... Annals of the rheumatic diseases 75 (5), 916-923, 2016 | 83 | 2016 |
Persistent stromal fibroblast activation is present in chronic tendinopathy SG Dakin, CD Buckley, MH Al-Mossawi, R Hedley, FO Martinez, ... Arthritis research & therapy 19, 1-11, 2017 | 82 | 2017 |
miR-10b-5p is a novel Th17 regulator present in Th17 cells from ankylosing spondylitis L Chen, MH Al-Mossawi, A Ridley, T Sekine, A Hammitzsch, J De Wit, ... Annals of the rheumatic diseases 76 (3), 620-625, 2017 | 68 | 2017 |
Activation‐Induced Killer Cell Immunoglobulin‐like Receptor 3DL2 Binding to HLA–B27 Licenses Pathogenic T Cell Differentiation in Spondyloarthritis A Ridley, H Hatano, I Wong‐Baeza, J Shaw, KK Matthews, H Al‐Mossawi, ... Arthritis & rheumatology 68 (4), 901-914, 2016 | 56 | 2016 |
A randomized, placebo‐controlled phase III extension trial of the long‐term safety and tolerability of anifrolumab in active systemic lupus erythematosus KC Kalunian, R Furie, EF Morand, IN Bruce, S Manzi, Y Tanaka, ... Arthritis & Rheumatology 75 (2), 253-265, 2023 | 47 | 2023 |
Context-specific regulation of surface and soluble IL7R expression by an autoimmune risk allele H Al-Mossawi, N Yager, CA Taylor, E Lau, S Danielli, J de Wit, J Gilchrist, ... Nature Communications 10 (1), 4575, 2019 | 43 | 2019 |
RORγt inhibitors suppress TH17 responses in inflammatory arthritis and inflammatory bowel disease J de Wit, MH Al-Mossawi, MH Hühn, CV Arancibia-Cárcamo, K Doig, ... Journal of Allergy and Clinical Immunology 137 (3), 960-963, 2016 | 40 | 2016 |
Expression of aberrant HLA-B27 molecules is dependent on B27 dosage and peptide supply K McHugh, O Rysnik, S Kollnberger, J Shaw, L Utriainen, MH Al-Mossawi, ... Annals of the rheumatic diseases 73 (4), 763-770, 2014 | 32 | 2014 |
Inhibiting ex-vivo Th17 responses in Ankylosing Spondylitis by targeting Janus kinases A Hammitzsch, L Chen, J de Wit, MH Al-Mossawi, A Ridley, T Sekine, ... Scientific Reports 8 (1), 15645, 2018 | 31 | 2018 |
Single cell analysis of spondyloarthritis regulatory T cells identifies distinct synovial gene expression patterns and clonal fates D Simone, F Penkava, A Ridley, S Sansom, MH Al-Mossawi, P Bowness Communications biology 4 (1), 1395, 2021 | 30 | 2021 |
Ex vivo mass cytometry analysis reveals a profound myeloid proinflammatory signature in psoriatic arthritis synovial fluid N Yager, S Cole, AL Lara, A Maroof, F Penkava, JC Knight, P Bowness, ... Annals of the Rheumatic Diseases 80 (12), 1559-1567, 2021 | 24 | 2021 |
The role of natural killer cells, gamma delta T-cells and other innate immune cells in spondyloarthritis MH Al-Mossawi, A Ridley, S Kiedel, P Bowness Current opinion in rheumatology 25 (4), 434-439, 2013 | 24 | 2013 |
Identification of human tendon cell populations in healthy and diseased tissue using combined single cell transcriptomics and proteomics AR Kendal, T Layton, H Al-Mossawi, R Brown, C Loizou, M Rogers, ... BioRxIV, 2019.12. 09.869933, 2019 | 12 | 2019 |
Novel therapeutic targets in axial spondyloarthritis C Worth, P Bowness, M Hussein Al-Mossawi Current Treatment Options in Rheumatology 4, 174-182, 2018 | 8 | 2018 |