| Senolytics improve physical function and increase lifespan in old age M Xu, T Pirtskhalava, JN Farr, BM Weigand, AK Palmer, MM Weivoda, ... Nature medicine 24 (8), 1246-1256, 2018 | 684 | 2018 |
| Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence G Hewitt, D Jurk, FDM Marques, C Correia-Melo, T Hardy, A Gackowska, ... Nature communications 3 (1), 1-9, 2012 | 584 | 2012 |
| DNA damage response and cellular senescence in tissues of aging mice C Wang, D Jurk, M Maddick, G Nelson, C Martin‐Ruiz, T Von Zglinicki Aging cell 8 (3), 311-323, 2009 | 578 | 2009 |
| Chronic inflammation induces telomere dysfunction and accelerates ageing in mice D Jurk, C Wilson, JF Passos, F Oakley, C Correia-Melo, L Greaves, ... Nature communications 5 (1), 1-14, 2014 | 527 | 2014 |
| A senescent cell bystander effect: Senescence‐induced senescence G Nelson, J Wordsworth, C Wang, D Jurk, C Lawless, C Martin‐Ruiz, ... Aging cell 11 (2), 345-349, 2012 | 456 | 2012 |
| Cellular senescence: defining a path forward V Gorgoulis, PD Adams, A Alimonti, DC Bennett, O Bischof, C Bishop, ... Cell 179 (4), 813-827, 2019 | 435 | 2019 |
| Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice CM Roos, B Zhang, AK Palmer, MB Ogrodnik, T Pirtskhalava, NM Thalji, ... Aging cell 15 (5), 973-977, 2016 | 378 | 2016 |
| Cellular senescence drives age-dependent hepatic steatosis M Ogrodnik, S Miwa, T Tchkonia, D Tiniakos, CL Wilson, A Lahat, CP Day, ... Nature communications 8 (1), 1-12, 2017 | 364 | 2017 |
| Mitochondria are required for pro‐ageing features of the senescent phenotype C Correia‐Melo, FDM Marques, R Anderson, G Hewitt, R Hewitt, J Cole, ... The EMBO journal 35 (7), 724-742, 2016 | 341 | 2016 |
| Postmitotic neurons develop a p21‐dependent senescence‐like phenotype driven by a DNA damage response D Jurk, C Wang, S Miwa, M Maddick, V Korolchuk, A Tsolou, ES Gonos, ... Aging cell 11 (6), 996-1004, 2012 | 324 | 2012 |
| Quantitative assessment of markers for cell senescence C Lawless, C Wang, D Jurk, A Merz, T von Zglinicki, JF Passos Experimental gerontology 45 (10), 772-778, 2010 | 237 | 2010 |
| Transplanted senescent cells induce an osteoarthritis-like condition in mice M Xu, EW Bradley, MM Weivoda, SM Hwang, T Pirtskhalava, T Decklever, ... The Journals of Gerontology: Series A 72 (6), 780-785, 2017 | 165 | 2017 |
| Targeting senescent cells alleviates obesity‐induced metabolic dysfunction AK Palmer, M Xu, Y Zhu, T Pirtskhalava, MM Weivoda, CM Hachfeld, ... Aging cell 18 (3), e12950, 2019 | 162 | 2019 |
| Obesity-induced cellular senescence drives anxiety and impairs neurogenesis M Ogrodnik, YI Zhu, LGP Langhi, T Tchkonia, P Krüger, E Fielder, ... Cell metabolism 29 (5), 1061-1077. e8, 2019 | 151 | 2019 |
| Oxidative stress and life histories: unresolved issues and current needs JR Speakman, JD Blount, AM Bronikowski, R Buffenstein, C Isaksson, ... Ecology and Evolution 5 (24), 5745-5757, 2015 | 145 | 2015 |
| Length‐independent telomere damage drives post‐mitotic cardiomyocyte senescence R Anderson, A Lagnado, D Maggiorani, A Walaszczyk, E Dookun, ... The EMBO journal 38 (5), e100492, 2019 | 133 | 2019 |
| A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline MG Tarragó, CCS Chini, KS Kanamori, GM Warner, A Caride, ... Cell metabolism 27 (5), 1081-1095. e10, 2018 | 116 | 2018 |
| Adult-onset, short-term dietary restriction reduces cell senescence in mice C Wang, M Maddick, S Miwa, D Jurk, R Czapiewski, G Saretzki, ... Aging (Albany NY) 2 (9), 555, 2010 | 115 | 2010 |
| NFκB1 is a suppressor of neutrophil-driven hepatocellular carcinoma CL Wilson, D Jurk, N Fullard, P Banks, A Page, S Luli, AM Elsharkawy, ... Nature communications 6 (1), 1-15, 2015 | 106 | 2015 |
| DNA damage response at telomeres contributes to lung aging and chronic obstructive pulmonary disease J Birch, RK Anderson, C Correia-Melo, D Jurk, G Hewitt, FM Marques, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 309 …, 2015 | 88 | 2015 |
Joao PassosAssociate Professor, Mayo Clinic, USAVerified email at mayo.edu
