A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity TM Frayling, NJ Timpson, MN Weedon, E Zeggini, RM Freathy, ... Science 316 (5826), 889-894, 2007 | 5661 | 2007 |
Genetic studies of body mass index yield new insights for obesity biology AE Locke, B Kahali, SI Berndt, AE Justice, TH Pers, FR Day, C Powell, ... Nature 518 (7538), 197-206, 2015 | 4748 | 2015 |
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index EK Speliotes, CJ Willer, SI Berndt, KL Monda, G Thorleifsson, AU Jackson, ... Nature genetics 42 (11), 937-948, 2010 | 3554 | 2010 |
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk J Dupuis, C Langenberg, I Prokopenko, R Saxena, N Soranzo, ... Nature genetics 42 (2), 105-116, 2010 | 2546 | 2010 |
New genetic loci link adipose and insulin biology to body fat distribution D Shungin, TW Winkler, DC Croteau-Chonka, T Ferreira, AE Locke, ... Nature 518 (7538), 187-196, 2015 | 1639 | 2015 |
Common variants near MC4R are associated with fat mass, weight and risk of obesity RJF Loos, CM Lindgren, S Li, E Wheeler, JH Zhao, I Prokopenko, ... Nature genetics 40 (6), 768-775, 2008 | 1579 | 2008 |
The genetic architecture of type 2 diabetes C Fuchsberger, J Flannick, TM Teslovich, A Mahajan, V Agarwala, ... Nature 536 (7614), 41-47, 2016 | 1250 | 2016 |
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution IM Heid, AU Jackson, JC Randall, TW Winkler, L Qi, V Steinthorsdottir, ... Nature genetics 42 (11), 949-960, 2010 | 1108 | 2010 |
Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility International Multiple Sclerosis Genetics Consortium*†, ANZgene, ... Science 365 (6460), eaav7188, 2019 | 930 | 2019 |
Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression BP Fairfax, P Humburg, S Makino, V Naranbhai, D Wong, E Lau, L Jostins, ... Science 343 (6175), 1246949, 2014 | 824 | 2014 |
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture SI Berndt, S Gustafsson, R Mägi, A Ganna, E Wheeler, MF Feitosa, ... Nature genetics 45 (5), 501-512, 2013 | 762 | 2013 |
Dynamic consent: a patient interface for twenty-first century research networks J Kaye, EA Whitley, D Lund, M Morrison, H Teare, K Melham European journal of human genetics 23 (2), 141-146, 2015 | 731 | 2015 |
Rare and low-frequency coding variants alter human adult height E Marouli, M Graff, C Medina-Gomez, KS Lo, AR Wood, TR Kjaer, RS Fine, ... Nature 542 (7640), 186-190, 2017 | 657 | 2017 |
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution CM Lindgren, IM Heid, JC Randall, C Lamina, V Steinthorsdottir, L Qi, ... PLoS genetics 5 (6), e1000508, 2009 | 626 | 2009 |
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals Z Dastani, MF Hivert, N Timpson, JRB Perry, X Yuan, RA Scott, ... PLoS genetics 8 (3), e1002607, 2012 | 569 | 2012 |
Exome-wide association study of plasma lipids in> 300,000 individuals DJ Liu, GM Peloso, H Yu, AS Butterworth, X Wang, A Mahajan, ... Nature genetics 49 (12), 1758-1766, 2017 | 548 | 2017 |
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits JC Randall, TW Winkler, Z Kutalik, SI Berndt, AU Jackson, KL Monda, ... PLoS genetics 9 (6), e1003500, 2013 | 476 | 2013 |
The power of genetic diversity in genome-wide association studies of lipids SE Graham, SL Clarke, KHH Wu, S Kanoni, GJM Zajac, S Ramdas, ... Nature 600 (7890), 675-679, 2021 | 460 | 2021 |
Downregulation of adipose tissue fatty acid trafficking in obesity: a driver for ectopic fat deposition? SE McQuaid, L Hodson, MJ Neville, AL Dennis, J Cheeseman, ... Diabetes 60 (1), 47-55, 2011 | 436 | 2011 |
Common Variation in the FTO Gene Alters Diabetes-Related Metabolic Traits to the Extent Expected Given Its Effect on BMI RM Freathy, NJ Timpson, DA Lawlor, A Pouta, Y Ben-Shlomo, ... Diabetes 57 (5), 1419-1426, 2008 | 436 | 2008 |