| Role of the base in Buchwald–Hartwig amination Y Sunesson, E Lime, SO Nilsson Lill, RE Meadows, PO Norrby The Journal of organic chemistry 79 (24), 11961-11969, 2014 | 133 | 2014 |
| Online quantitative mass spectrometry for the rapid adaptive optimisation of automated flow reactors JD Robert, A JohnáBlacker Reaction Chemistry & Engineering 1 (1), 96-100, 2016 | 132 | 2016 |
| Self-optimisation of the final stage in the synthesis of EGFR kinase inhibitor AZD9291 using an automated flow reactor N Holmes, GR Akien, AJ Blacker, RL Woodward, RE Meadows, ... Reaction Chemistry & Engineering 1 (4), 366-371, 2016 | 114 | 2016 |
| Catalytic activity of biomass-supported Pd nanoparticles: influence of the biological component in catalytic efficacy and potential application in ‘green’synthesis of fine … K Deplanche, JA Bennett, IP Mikheenko, J Omajali, AS Wells, ... Applied Catalysis B: Environmental 147, 651-665, 2014 | 106 | 2014 |
| Rapid virtual screening of enantioselective catalysts using CatVS AR Rosales, J Wahlers, E Limé, RE Meadows, KW Leslie, R Savin, F Bell, ... Nature Catalysis 2 (1), 41-45, 2019 | 105 | 2019 |
| Enabling the scale-up of a key asymmetric hydrogenation step in the synthesis of an API using continuous flow solid-supported catalysis Z Amara, M Poliakoff, R Duque, D Geier, G Franciò, CM Gordon, ... Organic Process Research & Development 20 (7), 1321-1327, 2016 | 69 | 2016 |
| A simple synthetic entryway into palladium cross-coupling catalysis CM Zinser, F Nahra, M Brill, RE Meadows, DB Cordes, AMZ Slawin, ... Chemical communications 53 (57), 7990-7993, 2017 | 62 | 2017 |
| A continuous process for Buchwald–Hartwig amination at micro-, lab-, and mesoscale using a novel reactor concept S Falß, G Tomaiuolo, A Perazzo, P Hodgson, P Yaseneva, J Zakrzewski, ... Organic Process Research & Development 20 (2), 558-567, 2016 | 61 | 2016 |
| Use of ω-transaminase enzyme chemistry in the synthesis of a JAK2 kinase inhibitor L Frodsham, M Golden, S Hard, MN Kenworthy, DJ Klauber, K Leslie, ... Organic Process Research & Development 17 (9), 1123-1130, 2013 | 49 | 2013 |
| Recyclable NHC catalyst for the development of a generalized approach to continuous Buchwald–Hartwig reaction and workup A Chartoire, C Claver, M Corpet, J Krinsky, J Mayen, D Nelson, SP Nolan, ... Organic Process Research & Development 20 (2), 551-557, 2016 | 46 | 2016 |
| Efficient Synthesis of (S)-1-(5-Fluoropyrimidin-2-yl)ethylamine Using an ω-Transaminase Biocatalyst in a Two-Phase System RE Meadows, KR Mulholland, M Schurmann, M Golden, H Kierkels, ... Organic Process Research & Development 17 (9), 1117-1122, 2013 | 44 | 2013 |
| Towards environmentally friendlier Suzuki–Miyaura reactions with precursors of Pd-NHC (NHC= N-heterocyclic carbene) complexes CM Zinser, KG Warren, RE Meadows, F Nahra, AM Al-Majid, A Barakat, ... Green chemistry 20 (14), 3246-3252, 2018 | 43 | 2018 |
| Continuous flow Buchwald–Hartwig amination of a pharmaceutical intermediate P Yaseneva, P Hodgson, J Zakrzewski, S Falß, RE Meadows, AA Lapkin Reaction Chemistry & Engineering 1 (2), 229-238, 2016 | 43 | 2016 |
| Steric effects in palladium-catalysed amination of aryl triflates and nonaflates with the primary amines PhCH (R) NH2 (R= H, Me) RE Meadows, S Woodward Tetrahedron 64 (7), 1218-1224, 2008 | 36 | 2008 |
| Process development of a Suzuki reaction used in the manufacture of lanabecestat IW Ashworth, AD Campbell, JH Cherryman, J Clark, A Crampton, ... Organic Process Research & Development 22 (12), 1801-1808, 2018 | 30 | 2018 |
| A microfluidic approach for flexible and efficient operation of a cross-coupling reactive flow A Perazzo, G Tomaiuolo, L Sicignano, G Toscano, RE Meadows, ... RSC advances 5 (78), 63786-63792, 2015 | 19 | 2015 |
| Efficient Synthesis of 2‐Methyl Derivatives of 1, 1′‐Bi (2‐naphthol) and 1, 1′‐Bi (2‐phenols) M Solinas, RE Meadows, C Wilson, AJ Blake, S Woodward European journal of organic chemistry 2007 (10), 1613-1623, 2007 | 14 | 2007 |
| Synthetic Route Design of AZD4635, an A2AR Antagonist MM Littleson, AD Campbell, A Clarke, M Dow, G Ensor, MC Evans, ... Organic Process Research & Development 23 (7), 1407-1419, 2019 | 11 | 2019 |
| A General Liquid–Liquid Partitioning Equation and Its Consequences: Learning from the pH Dependent Extraction of a Pharmaceutical Intermediate IW Ashworth, RE Meadows The Journal of Organic Chemistry 83 (7), 4270-4274, 2018 | 9 | 2018 |
| From Milligram to Kilogram Manufacture of AZD4573: Making It Possible by Application of Enzyme-, Iridium-, and Palladium-Catalyzed Key Transformations S Karlsson, H Benson, C Cook, G Currie, J Dubiez, H Emtenäs, ... Organic Process Research & Development 26 (3), 601-615, 2021 | 7 | 2021 |
