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Laszlo Hosszu
Laszlo Hosszu
Investigator Scientist, MRC Prion Unit
Verified email at prion.ucl.ac.uk
Title
Cited by
Cited by
Year
Location and properties of metal-binding sites on the human prion protein
GS Jackson, I Murray, LLP Hosszu, N Gibbs, JP Waltho, AR Clarke, ...
Proceedings of the National Academy of Sciences 98 (15), 8531-8535, 2001
6502001
Reversible conversion of monomeric human prion protein between native and fibrilogenic conformations
GS Jackson, LLP Hosszu, A Power, AF Hill, J Kenney, H Saibil, ...
Science 283 (5409), 1935-1937, 1999
4761999
Structural mobility of the human prion protein probed by backbone hydrogen exchange
LLP Hosszu, NJ Baxter, GS Jackson, A Power, AR Clarke, JP Waltho, ...
Nature structural biology 6 (8), 740-743, 1999
1951999
Multiple folding pathways for heterologously expressed human prion protein
GS Jackson, AF Hill, C Joseph, L Hosszu, A Power, JP Waltho, AR Clarke, ...
Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular …, 1999
1571999
Multiple forms of copper (II) co-ordination occur throughout the disordered N-terminal region of the prion protein at pH 7.4
MA Wells, C Jelinska, LLP Hosszu, CJ Craven, AR Clarke, J Collinge, ...
Biochemical Journal 400 (3), 501-510, 2006
1012006
A reassessment of copper (II) binding in the full-length prion protein
MA Wells, GS Jackson, S Jones, LLP Hosszu, CJ Craven, AR Clarke, ...
Biochemical Journal 399 (3), 435-444, 2006
982006
Characterisation of low free-energy excited states of folded proteins
NJ Baxter, LLP Hosszu, JP Waltho, MP Williamson
Journal of molecular biology 284 (5), 1625-1639, 1998
901998
The residue 129 polymorphism in human prion protein does not confer susceptibility to Creutzfeldt-Jakob disease by altering the structure or global stability of PrPC
LLP Hosszu, GS Jackson, CR Trevitt, S Jones, M Batchelor, D Bhelt, ...
Journal of Biological Chemistry 279 (27), 28515-28521, 2004
782004
Definable equilibrium states in the folding of human prion protein
LLP Hosszu, MA Wells, GS Jackson, S Jones, M Batchelor, AR Clarke, ...
Biochemistry 44 (50), 16649-16657, 2005
692005
Ex vivo mammalian prions are formed of paired double helical prion protein fibrils
C Terry, A Wenborn, N Gros, J Sells, S Joiner, LLP Hosszu, MH Tattum, ...
Open biology 6 (5), 160035, 2016
682016
Folding kinetics of the human prion protein probed by temperature jump
T Hart, LLP Hosszu, CR Trevitt, GS Jackson, JP Waltho, J Collinge, ...
Proceedings of the National Academy of Sciences 106 (14), 5651-5656, 2009
582009
Effects of domain dissection on the folding and stability of the 43 kDa protein PGK probed by NMR
MAC Reed, AM Hounslow, KH Sze, IG Barsukov, LLP Hosszu, AR Clarke, ...
Journal of molecular biology 330 (5), 1189-1201, 2003
532003
Topology, sequence evolution and folding dynamics of an immunoglobulin domain
MJ Parker, CE Dempsey, LLP Hosszu, JP Waltho, AR Clarke
Nature Structural Biology 5 (3), 194-198, 1998
491998
The H187R Mutation of the Human Prion Protein Induces Conversion of Recombinant Prion Protein to the PrPSc-like Form
LLP Hosszu, MH Tattum, S Jones, CR Trevitt, MA Wells, JP Waltho, ...
Biochemistry 49 (40), 8729-8738, 2010
462010
Structure of a kinetic protein folding intermediate by equilibrium amide exchange.
LL Hosszu, CJ Craven, MJ Parker, M Lorch, J Spencer, AR Clarke, ...
Nature Structural Biology 4 (10), 801-804, 1997
461997
Conformational properties of β-PrP
LLP Hosszu, CR Trevitt, S Jones, M Batchelor, DJ Scott, GS Jackson, ...
Journal of Biological Chemistry 284 (33), 21981-21990, 2009
442009
Domain behavior during the folding of a thermostable phosphoglycerate kinase
MJ Parker, J Spencer, GS Jackson, SG Burston, LLP Hosszu, CJ Craven, ...
Biochemistry 35 (49), 15740-15752, 1996
381996
A systematic investigation of production of synthetic prions from recombinant prion protein
C Schmidt, J Fizet, F Properzi, M Batchelor, MK Sandberg, JA Edgeworth, ...
Open Biology 5 (12), 150165, 2015
312015
N-terminal domain of prion protein directs its oligomeric association
CR Trevitt, LLP Hosszu, M Batchelor, S Panico, C Terry, AJ Nicoll, E Risse, ...
Journal of Biological Chemistry 289 (37), 25497-25508, 2014
302014
Is the structure of the N-domain of phosphoglycerate kinase affected by isolation from the intact molecule?
LLP Hosszu, CJ Craven, J Spencer, MJ Parker, AR Clarke, M Kelly, ...
Biochemistry 36 (2), 333-340, 1997
231997
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