Location and properties of metal-binding sites on the human prion protein GS Jackson, I Murray, LLP Hosszu, N Gibbs, JP Waltho, AR Clarke, ... Proceedings of the National Academy of Sciences 98 (15), 8531-8535, 2001 | 650 | 2001 |
Reversible conversion of monomeric human prion protein between native and fibrilogenic conformations GS Jackson, LLP Hosszu, A Power, AF Hill, J Kenney, H Saibil, ... Science 283 (5409), 1935-1937, 1999 | 476 | 1999 |
Structural mobility of the human prion protein probed by backbone hydrogen exchange LLP Hosszu, NJ Baxter, GS Jackson, A Power, AR Clarke, JP Waltho, ... Nature structural biology 6 (8), 740-743, 1999 | 195 | 1999 |
Multiple folding pathways for heterologously expressed human prion protein GS Jackson, AF Hill, C Joseph, L Hosszu, A Power, JP Waltho, AR Clarke, ... Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular …, 1999 | 157 | 1999 |
Multiple forms of copper (II) co-ordination occur throughout the disordered N-terminal region of the prion protein at pH 7.4 MA Wells, C Jelinska, LLP Hosszu, CJ Craven, AR Clarke, J Collinge, ... Biochemical Journal 400 (3), 501-510, 2006 | 101 | 2006 |
A reassessment of copper (II) binding in the full-length prion protein MA Wells, GS Jackson, S Jones, LLP Hosszu, CJ Craven, AR Clarke, ... Biochemical Journal 399 (3), 435-444, 2006 | 98 | 2006 |
Characterisation of low free-energy excited states of folded proteins NJ Baxter, LLP Hosszu, JP Waltho, MP Williamson Journal of molecular biology 284 (5), 1625-1639, 1998 | 90 | 1998 |
The residue 129 polymorphism in human prion protein does not confer susceptibility to Creutzfeldt-Jakob disease by altering the structure or global stability of PrPC LLP Hosszu, GS Jackson, CR Trevitt, S Jones, M Batchelor, D Bhelt, ... Journal of Biological Chemistry 279 (27), 28515-28521, 2004 | 78 | 2004 |
Definable equilibrium states in the folding of human prion protein LLP Hosszu, MA Wells, GS Jackson, S Jones, M Batchelor, AR Clarke, ... Biochemistry 44 (50), 16649-16657, 2005 | 69 | 2005 |
Ex vivo mammalian prions are formed of paired double helical prion protein fibrils C Terry, A Wenborn, N Gros, J Sells, S Joiner, LLP Hosszu, MH Tattum, ... Open biology 6 (5), 160035, 2016 | 68 | 2016 |
Folding kinetics of the human prion protein probed by temperature jump T Hart, LLP Hosszu, CR Trevitt, GS Jackson, JP Waltho, J Collinge, ... Proceedings of the National Academy of Sciences 106 (14), 5651-5656, 2009 | 58 | 2009 |
Effects of domain dissection on the folding and stability of the 43 kDa protein PGK probed by NMR MAC Reed, AM Hounslow, KH Sze, IG Barsukov, LLP Hosszu, AR Clarke, ... Journal of molecular biology 330 (5), 1189-1201, 2003 | 53 | 2003 |
Topology, sequence evolution and folding dynamics of an immunoglobulin domain MJ Parker, CE Dempsey, LLP Hosszu, JP Waltho, AR Clarke Nature Structural Biology 5 (3), 194-198, 1998 | 49 | 1998 |
The H187R Mutation of the Human Prion Protein Induces Conversion of Recombinant Prion Protein to the PrPSc-like Form LLP Hosszu, MH Tattum, S Jones, CR Trevitt, MA Wells, JP Waltho, ... Biochemistry 49 (40), 8729-8738, 2010 | 46 | 2010 |
Structure of a kinetic protein folding intermediate by equilibrium amide exchange. LL Hosszu, CJ Craven, MJ Parker, M Lorch, J Spencer, AR Clarke, ... Nature Structural Biology 4 (10), 801-804, 1997 | 46 | 1997 |
Conformational properties of β-PrP LLP Hosszu, CR Trevitt, S Jones, M Batchelor, DJ Scott, GS Jackson, ... Journal of Biological Chemistry 284 (33), 21981-21990, 2009 | 44 | 2009 |
Domain behavior during the folding of a thermostable phosphoglycerate kinase MJ Parker, J Spencer, GS Jackson, SG Burston, LLP Hosszu, CJ Craven, ... Biochemistry 35 (49), 15740-15752, 1996 | 38 | 1996 |
A systematic investigation of production of synthetic prions from recombinant prion protein C Schmidt, J Fizet, F Properzi, M Batchelor, MK Sandberg, JA Edgeworth, ... Open Biology 5 (12), 150165, 2015 | 31 | 2015 |
N-terminal domain of prion protein directs its oligomeric association CR Trevitt, LLP Hosszu, M Batchelor, S Panico, C Terry, AJ Nicoll, E Risse, ... Journal of Biological Chemistry 289 (37), 25497-25508, 2014 | 30 | 2014 |
Is the structure of the N-domain of phosphoglycerate kinase affected by isolation from the intact molecule? LLP Hosszu, CJ Craven, J Spencer, MJ Parker, AR Clarke, M Kelly, ... Biochemistry 36 (2), 333-340, 1997 | 23 | 1997 |