| A Novel Biological Activity of Praziquantel Requiring Voltage-Operated Ca2+ Channel β Subunits: Subversion of Flatworm Regenerative Polarity T Nogi, D Zhang, JD Chan, JS Marchant PLoS neglected tropical diseases 3 (6), e464, 2009 | 125 | 2009 |
| The anthelmintic drug praziquantel activates a schistosome transient receptor potential channel SK Park, GS Gunaratne, EG Chulkov, F Moehring, P McCusker, PI Dosa, ... Journal of Biological Chemistry 294 (49), 18873-18880, 2019 | 89 | 2019 |
| Ca2+ channels and praziquantel: a view from the free world JD Chan, M Zarowiecki, JS Marchant Parasitology international 62 (6), 619-628, 2013 | 81 | 2013 |
| Tuberculosis genes expressed during persistence and reactivation in the resistant rabbit model AK Kesavan, M Brooks, JA Tufariello, J Chan, YC Manabe Tuberculosis 89 (1), 17-21, 2009 | 66 | 2009 |
| The anthelmintic praziquantel is a human serotoninergic G-protein-coupled receptor ligand JD Chan, PM Cupit, GS Gunaratne, JD McCorvy, Y Yang, K Stoltz, ... Nature communications 8 (1), 1910, 2017 | 64 | 2017 |
| ‘Death and Axes’: Unexpected Ca2+ Entry Phenologs Predict New Anti-schistosomal Agents JD Chan, PN Agbedanu, M Zamanian, SM Gruba, CL Haynes, TA Day, ... PLoS pathogens 10 (2), e1003942, 2014 | 45 | 2014 |
| Opposing roles of voltage-gated Ca2+ channels in neuronal control of regenerative patterning D Zhang, JD Chan, T Nogi, JS Marchant Journal of Neuroscience 31 (44), 15983-15995, 2011 | 45 | 2011 |
| A Miniaturized Screen of a Schistosoma mansoni Serotonergic G Protein-Coupled Receptor Identifies Novel Classes of Parasite-Selective Inhibitors JD Chan, JD McCorvy, S Acharya, ME Johns, TA Day, BL Roth, ... PLoS pathogens 12 (5), e1005651, 2016 | 34 | 2016 |
| Ergot alkaloids (Re) generate new leads as antiparasitics JD Chan, PN Agbedanu, T Grab, M Zamanian, PI Dosa, TA Day, ... PLoS neglected tropical diseases 9 (9), e0004063, 2015 | 29 | 2015 |
| Unique pharmacological properties of serotoninergic G-protein coupled receptors from cestodes F Camicia, AM Celentano, ME Johns, JD Chan, L Maldonado, H Vaca, ... PLoS neglected tropical diseases 12 (2), e0006267, 2018 | 28 | 2018 |
| Pharmacological profiling an abundantly expressed schistosome serotonergic GPCR identifies nuciferine as a potent antagonist JD Chan, S Acharya, TA Day, JS Marchant International Journal for Parasitology: Drugs and Drug Resistance 6 (3), 364-370, 2016 | 22 | 2016 |
| Utilizing the planarian voltage-gated ion channel transcriptome to resolve a role for a Ca2+ channel in neuromuscular function and regeneration JD Chan, D Zhang, X Liu, M Zarowiecki, M Berriman, JS Marchant Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1864 (6), 1036-1045, 2017 | 21 | 2017 |
| Pharmacological and functional genetic assays to manipulate regeneration of the planarian Dugesia japonica JD Chan, JS Marchant JoVE (Journal of Visualized Experiments), e3058, 2011 | 19 | 2011 |
| Kinetic profiling an abundantly expressed planarian serotonergic GPCR identifies bromocriptine as a perdurant antagonist JD Chan, T Grab, JS Marchant International Journal for Parasitology: Drugs and Drug Resistance 6 (3), 356-363, 2016 | 18 | 2016 |
| High-content approaches to anthelmintic drug screening M Zamanian, JD Chan Trends in parasitology 37 (9), 780-789, 2021 | 17 | 2021 |
| Dataset for a Dugesia japonica de novo transcriptome assembly, utilized for defining the voltage-gated like ion channel superfamily JD Chan, D Zhang, X Liu, MZ Zarowiecki, M Berriman, JS Marchant Data in brief 9, 1044-1047, 2016 | 14 | 2016 |
| Coalescing beneficial host and deleterious antiparasitic actions as an antischistosomal strategy JD Chan, TA Day, JS Marchant Elife 7, e35755, 2018 | 13 | 2018 |
| Structure-activity profiling of alkaloid natural product pharmacophores against a Schistosoma serotonin receptor JS Marchant, WW Harding, JD Chan International Journal for Parasitology: Drugs and Drug Resistance 8 (3), 550-558, 2018 | 12 | 2018 |
| Making heads or tails: planarian stem cells in the classroom MC Srougi, J Thomas-Swanik, JD Chan, JS Marchant, S Carson Journal of microbiology & biology education 15 (1), 18-25, 2014 | 9 | 2014 |
| Schistosoma mansoni alter transcription of immunomodulatory gene products following in vivo praziquantel exposure P McCusker, CM Rohr, JD Chan PLoS Neglected Tropical Diseases 15 (3), e0009200, 2021 | 8 | 2021 |
