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Ian Seim
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Year
Mucus accumulation in the lungs precedes structural changes and infection in children with cystic fibrosis
CR Esther Jr, MS Muhlebach, C Ehre, DB Hill, MC Wolfgang, M Kesimer, ...
Science translational medicine 11 (486), eaav3488, 2019
1802019
Membrane surfaces regulate assembly of ribonucleoprotein condensates
WT Snead, AP Jalihal, TM Gerbich, I Seim, Z Hu, AS Gladfelter
Nature cell biology 24 (4), 461-470, 2022
762022
Dilute phase oligomerization can oppose phase separation and modulate material properties of a ribonucleoprotein condensate
I Seim, AE Posey, WT Snead, BM Stormo, D Klotsa, RV Pappu, ...
Proceedings of the National Academy of Sciences 119 (13), e2120799119, 2022
512022
Technological strategies to estimate and control diffusive passage times through the mucus barrier in mucosal drug delivery
JM Newby, I Seim, M Lysy, Y Ling, J Huckaby, SK Lai, MG Forest
Advanced drug delivery reviews 124, 64-81, 2018
452018
Double-stranded RNA drives SARS-CoV-2 nucleocapsid protein to undergo phase separation at specific temperatures
CA Roden, Y Dai, CA Giannetti, I Seim, M Lee, R Sealfon, GA McLaughlin, ...
Nucleic acids research 50 (14), 8168-8192, 2022
402022
Designed, highly expressing, thermostable dengue virus 2 envelope protein dimers elicit quaternary epitope antibodies
ST Kudlacek, S Metz, D Thiono, AM Payne, TTN Phan, S Tian, ...
Science advances 7 (42), eabg4084, 2021
202021
Role of spatial patterning of N-protein interactions in SARS-CoV-2 genome packaging
I Seim, CA Roden, AS Gladfelter
Biophysical journal 120 (14), 2771-2784, 2021
192021
Mucus and mucus flake composition and abundance reflect inflammatory and infection status in cystic fibrosis
MR Markovetz, IC Garbarine, CB Morrison, WJ Kissner, I Seim, MG Forest, ...
Journal of Cystic Fibrosis 21 (6), 959-966, 2022
142022
Dynamical control enables the formation of demixed biomolecular condensates
AZ Lin, KM Ruff, F Dar, A Jalihal, MR King, JM Lalmansingh, AE Posey, ...
Nature Communications 14 (1), 7678, 2023
102023
Biophysical properties governing septin assembly
BL Woods, I Seim, J Liu, G McLaughlin, KS Cannon, AS Gladfelter
bioRxiv, 2021.03. 22.436414, 2021
72021
Mucus accumulation in the lungs precedes structural changes and infection in children with cystic fibrosis. Sci Transl Med 11: eaav3488
CR Esther, MS Muhlebach, C Ehre, DB Hill, MC Wolfgang, M Kesimer, ...
52019
Measurement error correction in particle tracking microrheology
Y Ling, M Lysy, I Seim, J Newby, DB Hill, J Cribb, MG Forest
The Annals of Applied Statistics 16 (3), 1747-1773, 2022
42022
A gene duplication of a septin reveals a developmentally regulated filament length control mechanism
KS Cannon, JM Vargas-Muniz, N Billington, I Seim, J Ekena, JR Sellers, ...
Journal of Cell Biology 222 (3), e202204063, 2023
32023
Biomolecular condensates in fungi are tuned to function at specific temperatures
BM Stormo, GA McLaughlin, LK Frederick, AP Jalihal, SJ Cole, I Seim, ...
bioRxiv, 2023
2023
Multi-Scale Studies of Molecular Self-Assembly in Biology
I Seim
The University of North Carolina at Chapel Hill, 2022
2022
Role of spatial patterning of N-protein interactions in SARS-CoV-2 genome packaging (preprint)
I Seim, C Roden, A Gladfelter
2021
Evidence that self-similar microrheology of highly entangled polymeric solutions scales robustly with, and is tunable by, polymer concentration
I Seim, JA Cribb, JM Newby, P Vasquez, M Lysy, MG Forest, DB Hill
arXiv preprint arXiv:1810.06649, 2018
2018
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