Ben Lehner
Ben Lehner
Coordinator of Systems Biology Program and ICREA Professor, CRG, Barcelona
Verified email at - Homepage
Cited by
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Systematic mapping of genetic interactions in Caenorhabditis elegans identifies common modifiers of diverse signaling pathways
B Lehner, C Crombie, J Tischler, A Fortunato, AG Fraser
Nature genetics 38 (8), 896-903, 2006
Chromatin organization is a major influence on regional mutation rates in human cancer cells
B Schuster-Böckler, B Lehner
nature 488 (7412), 504-507, 2012
3D structures of individual mammalian genomes studied by single-cell Hi-C
TJ Stevens, D Lando, S Basu, LP Atkinson, Y Cao, SF Lee, M Leeb, ...
Nature 544 (7648), 59-64, 2017
Synonymous mutations frequently act as driver mutations in human cancers
F Supek, B Miñana, J Valcárcel, T Gabaldón, B Lehner
Cell 156 (6), 1324-1335, 2014
In search of antisense
G Lavorgna, D Dahary, B Lehner, R Sorek, CM Sanderson, G Casari
Trends in biochemical sciences 29 (2), 88-94, 2004
Tissue specificity and the human protein interaction network
A Bossi, B Lehner
Molecular systems biology 5 (1), 260, 2009
A single gene network accurately predicts phenotypic effects of gene perturbation in Caenorhabditis elegans
I Lee, B Lehner, C Crombie, W Wong, AG Fraser, EM Marcotte
Nature genetics 40 (2), 181, 2008
Intrinsic protein disorder and interaction promiscuity are widely associated with dosage sensitivity
T Vavouri, JI Semple, R Garcia-Verdugo, B Lehner
Cell 138 (1), 198-208, 2009
Antisense transcripts in the human genome
B Lehner, G Williams, RD Campbell, CM Sanderson
Trends in Genetics 18 (2), 63-65, 2002
A first-draft human protein-interaction map
B Lehner, AG Fraser
Genome biology 5 (9), R63, 2004
Differential DNA mismatch repair underlies mutation rate variation across the human genome
F Supek, B Lehner
Nature 521 (7550), 81-84, 2015
Molecular mechanisms of epistasis within and between genes
B Lehner
Trends in Genetics 27 (8), 323-331, 2011
Selection to minimise noise in living systems and its implications for the evolution of gene expression
B Lehner
Molecular systems biology 4 (1), 170, 2008
Transgenerational transmission of environmental information in C. elegans
A Klosin, E Casas, C Hidalgo-Carcedo, T Vavouri, B Lehner
Science 356 (6335), 320-323, 2017
Genotype to phenotype: lessons from model organisms for human genetics
B Lehner
Nature Reviews Genetics 14 (3), 168-178, 2013
Predicting mutation outcome from early stochastic variation in genetic interaction partners
A Burga, MO Casanueva, B Lehner
Nature 480 (7376), 250-253, 2011
The rules and impact of nonsense-mediated mRNA decay in human cancers
RGH Lindeboom, F Supek, B Lehner
Nature genetics 48 (10), 1112-1118, 2016
A protein interaction framework for human mRNA degradation
B Lehner, CM Sanderson
Genome Research 14 (7), 1315-1323, 2004
Fitness trade-offs and environmentally induced mutation buffering in isogenic C. elegans
MO Casanueva, A Burga, B Lehner
Science 335 (6064), 82-85, 2012
Evolutionary plasticity of genetic interaction networks
J Tischler, B Lehner, AG Fraser
Nature genetics 40 (4), 390-391, 2008
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