Jorge I. Castillo-Quan
Jorge I. Castillo-Quan
Joslin Diabetes Center, Harvard Medical School
Verified email at - Homepage
Cited by
Cited by
From white to brown fat through the PGC-1α-dependent myokine irisin: implications for diabetes and obesity
JI Castillo-Quan
Disease models & mechanisms 5 (3), 293-295, 2012
Lithium promotes longevity through GSK3/NRF2-dependent hormesis
JI Castillo-Quan, L Li, KJ Kinghorn, DK Ivanov, LS Tain, C Slack, F Kerr, ...
Cell reports 15 (3), 638-650, 2016
Loss of PLA2G6 leads to elevated mitochondrial lipid peroxidation and mitochondrial dysfunction
KJ Kinghorn, JI Castillo-Quan, F Bartolome, PR Angelova, L Li, S Pope, ...
Brain 138 (7), 1801-1816, 2015
Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer’s disease
F Kerr, O Sofola-Adesakin, DK Ivanov, J Gatliff, B Gomez Perez-Nievas, ...
PLoS genetics 13 (3), e1006593, 2017
A Drosophila Model of Neuronopathic Gaucher Disease Demonstrates Lysosomal-Autophagic Defects and Altered mTOR Signalling and Is Functionally Rescued …
KJ Kinghorn, S Grönke, JI Castillo-Quan, NS Woodling, L Li, E Sirka, ...
Journal of Neuroscience 36 (46), 11654-11670, 2016
Depresión y diabetes: de la epidemiología a la neurobiología
JI Castillo-Quan, DJ Barrera-Buenfil, JM Pérez-Osorio, ...
Rev Neurol 51 (6), 347-359, 2010
Lithium suppresses Aβ pathology by inhibiting translation in an adult Drosophila model of Alzheimer’s disease.
O Sofola-Adesakin, JI Castillo-Quan, C Rallis, LS Tain, I Bjedov, I Rogers, ...
Frontiers in aging neuroscience 6, 190, 2014
Parkin’control: regulation of PGC-1α through PARIS in Parkinson’s disease
JI Castillo-Quan
Disease Models & Mechanisms 4 (4), 427-429, 2011
A triple drug combination targeting components of the nutrient-sensing network maximizes longevity
JI Castillo-Quan, LS Tain, KJ Kinghorn, L Li, S Grönke, Y Hinze, ...
Proceedings of the National Academy of Sciences 116 (42), 20817-20819, 2019
The emerging role of autophagic-lysosomal dysfunction in Gaucher disease and Parkinson's disease
KJ Kinghorn, AM Asghari, JI Castillo-Quan
Neural Regeneration Research 12 (3), 380, 2017
Untangling longevity, dauer, and healthspan in Caenorhabditis elegans insulin/IGF-1-signalling
CY Ewald, JI Castillo-Quan, TK Blackwell
Gerontology 64 (1), 96-104, 2018
Agephagy–Adapting autophagy for health during aging
ER Stead, JI Castillo-Quan, VEM Miguel, C Lujan, R Ketteler, KJ Kinghorn, ...
Frontiers in Cell and Developmental Biology, 308, 2019
Genetics and pharmacology of longevity: the road to therapeutics for healthy aging
JI Castillo-Quan, KJ Kinghorn, I Bjedov
Advances in Genetics 90, 1-101, 2015
Metformin: restraining nucleocytoplasmic shuttling to fight cancer and aging
JI Castillo-Quan, TK Blackwell
Cell 167 (7), 1670-1671, 2016
Insulin-cortisol interaction in depression and other neurological diseases: an alternative hypothesis
JI Castillo-Quan, A Herrera-González, JM Pérez-Osorio
Psychoneuroendocrinology 32 (7), 854-856, 2007
Fine-tuning autophagy maximises lifespan and is associated with changes in mitochondrial gene expression in Drosophila
I Bjedov, HM Cochemé, A Foley, D Wieser, NS Woodling, JI Castillo-Quan, ...
PLoS genetics 16 (11), e1009083, 2020
Nutritional genomics: an approach to the genome-environment interaction
F Xacur-Garcia, JI Castillo-Quan, VM Hernandez-Escalante, ...
Rev Med Chil 136, 1460-7, 2008
Cortisol secretion in patients with type 2 diabetes: relationship with chronic complications: response to Chiodini et al.
POJM Castillo-Quan, Jorge I
Diabetes Care 30 (6), 265-273, 2006
Mitochondrial dysfunction and defects in lipid homeostasis as therapeutic targets in neurodegeneration with brain iron accumulation
KJ Kinghorn, JI Castillo-Quan
Rare Diseases 4 (1), 1801-1816, 2016
Rosiglitazone effects to ameliorate Alzheimer’s disease pathogenic features: insulin signaling and neurotrophic factors
JI Castillo-Quan
The Journal of neuropsychiatry and clinical neurosciences 21 (3), 347-348, 2009
The system can't perform the operation now. Try again later.
Articles 1–20