| Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors AM Mendes‐Pereira, SA Martin, R Brough, A McCarthy, JR Taylor, JS Kim, ... EMBO molecular medicine 1 (6‐7), 315-322, 2009 | 732 | 2009 |
| PTEN deficiency in endometrioid endometrial adenocarcinomas predicts sensitivity to PARP inhibitors KJ Dedes, D Wetterskog, AM Mendes-Pereira, R Natrajan, MB Lambros, ... Science Translational Medicine 2 (53), 53ra75-53ra75, 2010 | 405 | 2010 |
| High-throughput RNA interference screening using pooled shRNA libraries and next generation sequencing D Sims, AM Mendes-Pereira, J Frankum, D Burgess, MA Cerone, ... Genome Biology 12 (10), R104, 2011 | 174 | 2011 |
| Functional viability profiles of breast cancer R Brough, JR Frankum, D Sims, A Mackay, AM Mendes-Pereira, I Bajrami, ... Cancer Discovery 1 (3), 260-273, 2011 | 171 | 2011 |
| Genome-wide functional screen identifies a compendium of genes affecting sensitivity to tamoxifen AM Mendes-Pereira, D Sims, T Dexter, K Fenwick, I Assiotis, I Kozarewa, ... Proceedings of the National Academy of Sciences, 2011 | 150 | 2011 |
| Synthetic lethal targeting of PTEN-deficient cancer cells using selective disruption of polynucleotide kinase/phosphatase TR Mereniuk, MAM El Gendy, AM Mendes-Pereira, CJ Lord, S Ghosh, ... Molecular cancer therapeutics 12 (10), 2135-2144, 2013 | 51 | 2013 |
| Integrated genomics and functional validation identifies malignant cell specific dependencies in triple negative breast cancer N Patel, D Weekes, K Drosopoulos, P Gazinska, E Noel, M Rashid, ... Nature communications 9 (1), 1044, 2018 | 48 | 2018 |
| Invasion-associated MMP-2 and MMP-9 are up-regulated intracellularly in concert with apoptosis linked to melanoma cell detachment AMM Pereira, M Strasberg-Rieber, M Rieber Clinical & experimental metastasis 22, 285-295, 2005 | 48 | 2005 |
| Genetic profiling of a central Venezuelan population using 15 STR markers that may be of forensic importance MA Chiurillo, A Morales, AM Mendes, N Lander, F Tovar, A Fuentes, ... Forensic science international 136 (1-3), 99-101, 2003 | 41 | 2003 |
| NLK is a novel therapeutic target for PTEN deficient tumour cells AM Mendes-Pereira, CJ Lord, A Ashworth PLoS One 7 (10), e47249, 2012 | 30 | 2012 |
| Functional viability profiles of breast cancer. Cancer Discov. 2011; 1: 260–273. doi: 10.1158/2159-8290 R Brough, JR Frankum, D Sims, A Mackay, AM Mendes-Pereira, I Bajrami, ... CD-11-0107.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 22 | |
| Functional screening reveals HORMAD1-driven gene dependencies associated with translesion synthesis and replication stress tolerance D Tarantino, C Walker, D Weekes, H Pemberton, K Davidson, G Torga, ... Oncogene 41 (32), 3969-3977, 2022 | 11 | 2022 |
| Preclinical evaluation of PARP inhibition as a treatment for endometrioid endometrial carcinomas. KJ Dedes, D Wetterskog, AM Mendes-Pereira, R Vatcheva, R Natrajan, ... Journal of Clinical Oncology 28 (15_suppl), 5065-5065, 2010 | 3 | 2010 |
| The anion channel GPR89 is a novel oncogene associated with tumour specific dependency in breast cancer R Ferro, A Carroll, A Mendes-Pereira, V Reen, I Roxanis, S Annunziato, ... European Journal of Cancer 174, S50, 2022 | | 2022 |
Christopher LordProfessor of Cancer Genomics, Institute of Cancer Research, London, UKVerified email at icr.ac.uk
