Regulation of cell division by intrinsically unstructured proteins: intrinsic flexibility, modularity, and signaling conduits CA Galea, Y Wang, SG Sivakolundu, RW Kriwacki Biochemistry 47 (29), 7598-7609, 2008 | 291 | 2008 |
Mutations in RAB39B cause X-linked intellectual disability and early-onset Parkinson disease with α-synuclein pathology GR Wilson, JCH Sim, C McLean, M Giannandrea, CA Galea, JR Riseley, ... The American Journal of Human Genetics 95 (6), 729-735, 2014 | 246 | 2014 |
Engineering a stable and selective peptide blocker of the Kv1. 3 channel in T lymphocytes MW Pennington, C Beeton, CA Galea, BJ Smith, V Chi, KP Monaghan, ... Molecular pharmacology 75 (4), 762-773, 2009 | 163 | 2009 |
Compound heterozygous FXN mutations and clinical outcome in friedreich ataxia CA Galea, A Huq, PJ Lockhart, G Tai, LA Corben, EM Yiu, LC Gurrin, ... Annals of neurology 79 (3), 485-495, 2016 | 157 | 2016 |
Role of intrinsic flexibility in signal transduction mediated by the cell cycle regulator, p27Kip1 CA Galea, A Nourse, Y Wang, SG Sivakolundu, WT Heller, RW Kriwacki Journal of molecular biology 376 (3), 827-838, 2008 | 149 | 2008 |
Mutations in DCC cause isolated agenesis of the corpus callosum with incomplete penetrance APL Marsh, D Heron, TJ Edwards, A Quartier, C Galea, C Nava, ... Nature genetics 49 (4), 511-514, 2017 | 104 | 2017 |
Inhibition of heme biosynthesis prevents transcription of iron uptake genes in yeast RJ Crisp, A Pollington, C Galea, S Jaron, Y Yamaguchi-Iwai, J Kaplan Journal of Biological Chemistry 278 (46), 45499-45506, 2003 | 97 | 2003 |
Association of villin with phosphatidylinositol 4, 5-bisphosphate regulates the actin cytoskeleton N Kumar, P Zhao, A Tomar, CA Galea, S Khurana Journal of Biological Chemistry 279 (4), 3096-3110, 2004 | 92 | 2004 |
Reversible amyloid formation by the p53 tetramerization domain and a cancer-associated mutant AS Lee, C Galea, EL DiGiammarino, B Jun, G Murti, RC Ribeiro, ... Journal of molecular biology 327 (3), 699-709, 2003 | 92 | 2003 |
Large-scale analysis of thermo-stable, mammalian proteins provides insights into the intrinsically disordered proteome CA Galea, A High, JC Obenauer, A Mishra, CG Park, M Punta, ... Biophysical Journal 96 (3), 318a, 2009 | 90 | 2009 |
Proteomic studies of the intrinsically unstructured mammalian proteome CA Galea, VR Pagala, JC Obenauer, CG Park, CA Slaughter, ... Journal of proteome research 5 (10), 2839-2848, 2006 | 82 | 2006 |
DCC mutation update: Congenital mirror movements, isolated agenesis of the corpus callosum, and developmental split brain syndrome APL Marsh, TJ Edwards, C Galea, HM Cooper, EC Engle, SS Jamuar, ... Human mutation 39 (1), 23-39, 2018 | 70 | 2018 |
Domain structure and function of matrix metalloprotease 23 (MMP23): role in potassium channel trafficking CA Galea, HM Nguyen, K George Chandy, BJ Smith, RS Norton Cellular and molecular life sciences 71, 1191-1210, 2014 | 48 | 2014 |
A helical conotoxin from Conus imperialis has a novel cysteine framework and defines a new superfamily M Ye, KK Khoo, S Xu, M Zhou, N Boonyalai, MA Perugini, X Shao, C Chi, ... Journal of Biological Chemistry 287 (18), 14973-14983, 2012 | 47 | 2012 |
Modification of the substrate specificity of porcine pepsin for the enzymatic production of bovine hide gelatin CA Galea, BP Dalrymple, R Kuypers, R Blakeley Protein Science 9 (10), 1947-1959, 2000 | 43 | 2000 |
Thermodynamic characterization of interactions between p27Kip1 and activated and non-activated Cdk2: intrinsically unstructured proteins as thermodynamic tethers P Bowman, CA Galea, E Lacy, RW Kriwacki Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1764 (2), 182-189, 2006 | 40 | 2006 |
Intrinsic protein flexibility in regulation of cell proliferation: advantages for signaling and opportunities for novel therapeutics AV Follis, CA Galea, RW Kriwacki Fuzziness: Structural Disorder in Protein Complexes, 27-49, 2012 | 39 | 2012 |
Beyond loss of frataxin: the complex molecular pathology of Friedreich ataxia MAV Evans-Galea, PJ Lockhart, CA Galea, AJ Hannan, M Delatycki Discovery medicine 17 (91), 25-35, 2014 | 38 | 2014 |
A potent cyclic peptide targeting SPSB2 protein as a potential anti-infective agent BK Yap, EWW Leung, H Yagi, CA Galea, S Chhabra, DK Chalmers, ... Journal of Medicinal Chemistry 57 (16), 7006-7015, 2014 | 37 | 2014 |
Disruption of an intermonomer salt bridge in the p53 tetramerization domain results in an increased propensity to form amyloid fibrils C Galea, P Bowman, RW Kriwacki Protein science 14 (12), 2993-3003, 2005 | 36 | 2005 |