Ian R Humphreys
Ian R Humphreys
Verified email at cf.ac.uk
TitleCited byYear
Evolutionarily divergent herpesviruses modulate T cell activation by targeting the herpesvirus entry mediator cosignaling pathway
TC Cheung, IR Humphreys, KG Potter, PS Norris, HM Shumway, BR Tran, ...
Proceedings of the National Academy of Sciences of the United States of …, 2005
2052005
Interleukin-6 signaling drives fibrosis in unresolved inflammation
CA Fielding, GW Jones, RM McLoughlin, L McLeod, VJ Hammond, ...
Immunity 40 (1), 40-50, 2014
1632014
A critical role for OX40 in T cell–mediated immunopathology during lung viral infection
IR Humphreys, G Walzl, L Edwards, A Rae, S Hill, T Hussell
The Journal of experimental medicine 198 (8), 1237-1242, 2003
1282003
Cytomegalovirus exploits IL-10–mediated immune regulation in the salivary glands
IR Humphreys, C De Trez, A Kinkade, CA Benedict, M Croft, CF Ware
The Journal of experimental medicine 204 (5), 1217-1225, 2007
1242007
A role for dendritic cells in the dissemination of mycobacterial infection
IR Humphreys, GR Stewart, DJ Turner, J Patel, D Karamanou, ...
Microbes and infection 8 (5), 1339-1346, 2006
1202006
OX40 costimulation promotes persistence of cytomegalovirus-specific CD8 T Cells: A CD4-dependent mechanism
IR Humphreys, A Loewendorf, C De Trez, K Schneider, CA Benedict, ...
The Journal of Immunology 179 (4), 2195-2202, 2007
902007
The stress‐responsive chaperone α‐crystallin 2 is required for pathogenesis of Mycobacterium tuberculosis
GR Stewart, SM Newton, KA Wilkinson, IR Humphreys, HN Murphy, ...
Molecular microbiology 55 (4), 1127-1137, 2005
772005
Innate imprinting by the modified heat-labile toxin of Escherichia coli (LTK63) provides generic protection against lung infectious disease
AE Williams, L Edwards, IR Humphreys, R Snelgrove, A Rae, R Rappuoli, ...
The Journal of Immunology 173 (12), 7435-7443, 2004
592004
IL-10 restricts memory T cell inflation during cytomegalovirus infection
M Jones, K Ladell, KK Wynn, MA Stacey, MF Quigley, E Gostick, DA Price, ...
The Journal of Immunology 185 (6), 3583-3592, 2010
552010
Biphasic role of 4‐1BB in the regulation of mouse cytomegalovirus‐specific CD8+ T cells
IR Humphreys, SW Lee, M Jones, A Loewendorf, E Gostick, DA Price, ...
European journal of immunology 40 (10), 2762-2768, 2010
542010
Characterization in mice of the immunological properties of five allergenic acid anhydrides
RJ Dearman, EV Warbrick, IR Humphreys, I Kimber
Journal of Applied Toxicology 20 (3), 221-230, 2000
542000
OX40 ligation on activated T cells enhances the control of Cryptococcus neoformans and reduces pulmonary eosinophilia
IR Humphreys, L Edwards, G Walzl, AJ Rae, G Dougan, S Hill, T Hussell
The Journal of Immunology 170 (12), 6125-6132, 2003
482003
Neutrophils Recruited by IL-22 in Peripheral Tissues Function as TRAIL-Dependent Antiviral Effectors against MCMV
MA Stacey, M Marsden, TA Pham N, S Clare, G Dolton, G Stack, E Jones, ...
Cell host & microbe 15 (4), 471-483, 2014
452014
IL-10 restricts activation-induced death of NK cells during acute murine cytomegalovirus infection
MA Stacey, M Marsden, ECY Wang, GWG Wilkinson, IR Humphreys
The Journal of Immunology 187 (6), 2944-2952, 2011
452011
The death receptor 3/TL1A pathway is essential for efficient development of antiviral CD4+ and CD8+ T-cell immunity
JP Twohig, M Marsden, SM Cuff, JR Ferdinand, AM Gallimore, WV Perks, ...
The FASEB Journal 26 (8), 3575-3586, 2012
442012
Interleukin-10 regulates the inflammasome-driven augmentation of inflammatory arthritis and joint destruction
CJ Greenhill, GW Jones, MA Nowell, Z Newton, AK Harvey, AN Moideen, ...
Arthritis Research & Therapy 16 (5), 419, 2014
432014
TGF-β prevents eosinophilic lung disease but impairs pathogen clearance
AE Williams, IR Humphreys, M Cornere, L Edwards, A Rae, T Hussell
Microbes and infection 7 (3), 365-374, 2005
432005
Interleukins 5 and 13 characterize immune responses to respiratory sensitizing acid anhydrides
RJ Dearman, A Filby, IR Humphreys, I Kimber
Journal of Applied Toxicology 22 (5), 317-325, 2002
372002
A critical role for ICOS co‐stimulation in immune containment of pulmonary influenza virus infection
IR Humphreys, L Edwards, RJ Snelgrove, AJ Rae, AJ Coyle, T Hussell
European journal of immunology 36 (11), 2928-2938, 2006
282006
Prior exposure to live Mycobacterium bovis BCG decreases Cryptococcus neoformans-induced lung eosinophilia in a gamma interferon-dependent manner
G Walzl, IR Humphreys, BG Marshall, L Edwards, PJM Openshaw, ...
Infection and immunity 71 (6), 3384-3391, 2003
272003
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