|Evolutionarily divergent herpesviruses modulate T cell activation by targeting the herpesvirus entry mediator cosignaling pathway|
TC Cheung, IR Humphreys, KG Potter, PS Norris, HM Shumway, BR Tran, ...
Proceedings of the National Academy of Sciences of the United States of …, 2005
|Interleukin-6 signaling drives fibrosis in unresolved inflammation|
CA Fielding, GW Jones, RM McLoughlin, L McLeod, VJ Hammond, ...
Immunity 40 (1), 40-50, 2014
|A critical role for OX40 in T cell–mediated immunopathology during lung viral infection|
IR Humphreys, G Walzl, L Edwards, A Rae, S Hill, T Hussell
The Journal of experimental medicine 198 (8), 1237-1242, 2003
|Cytomegalovirus exploits IL-10–mediated immune regulation in the salivary glands|
IR Humphreys, C De Trez, A Kinkade, CA Benedict, M Croft, CF Ware
The Journal of experimental medicine 204 (5), 1217-1225, 2007
|A role for dendritic cells in the dissemination of mycobacterial infection|
IR Humphreys, GR Stewart, DJ Turner, J Patel, D Karamanou, ...
Microbes and infection 8 (5), 1339-1346, 2006
|OX40 costimulation promotes persistence of cytomegalovirus-specific CD8 T Cells: A CD4-dependent mechanism|
IR Humphreys, A Loewendorf, C De Trez, K Schneider, CA Benedict, ...
The Journal of Immunology 179 (4), 2195-2202, 2007
|The stress‐responsive chaperone α‐crystallin 2 is required for pathogenesis of Mycobacterium tuberculosis|
GR Stewart, SM Newton, KA Wilkinson, IR Humphreys, HN Murphy, ...
Molecular microbiology 55 (4), 1127-1137, 2005
|Innate imprinting by the modified heat-labile toxin of Escherichia coli (LTK63) provides generic protection against lung infectious disease|
AE Williams, L Edwards, IR Humphreys, R Snelgrove, A Rae, R Rappuoli, ...
The Journal of Immunology 173 (12), 7435-7443, 2004
|Biphasic role of 4‐1BB in the regulation of mouse cytomegalovirus‐specific CD8+ T cells|
IR Humphreys, SW Lee, M Jones, A Loewendorf, E Gostick, DA Price, ...
European journal of immunology 40 (10), 2762-2768, 2010
|IL-10 restricts memory T cell inflation during cytomegalovirus infection|
M Jones, K Ladell, KK Wynn, MA Stacey, MF Quigley, E Gostick, DA Price, ...
The Journal of Immunology 185 (6), 3583-3592, 2010
|Characterization in mice of the immunological properties of five allergenic acid anhydrides|
RJ Dearman, EV Warbrick, IR Humphreys, I Kimber
Journal of Applied Toxicology 20 (3), 221-230, 2000
|OX40 ligation on activated T cells enhances the control of Cryptococcus neoformans and reduces pulmonary eosinophilia|
IR Humphreys, L Edwards, G Walzl, AJ Rae, G Dougan, S Hill, T Hussell
The Journal of Immunology 170 (12), 6125-6132, 2003
|Neutrophils Recruited by IL-22 in Peripheral Tissues Function as TRAIL-Dependent Antiviral Effectors against MCMV|
MA Stacey, M Marsden, TA Pham N, S Clare, G Dolton, G Stack, E Jones, ...
Cell host & microbe 15 (4), 471-483, 2014
|IL-10 restricts activation-induced death of NK cells during acute murine cytomegalovirus infection|
MA Stacey, M Marsden, ECY Wang, GWG Wilkinson, IR Humphreys
The Journal of Immunology 187 (6), 2944-2952, 2011
|The death receptor 3/TL1A pathway is essential for efficient development of antiviral CD4+ and CD8+ T-cell immunity|
JP Twohig, M Marsden, SM Cuff, JR Ferdinand, AM Gallimore, WV Perks, ...
The FASEB Journal 26 (8), 3575-3586, 2012
|TGF-β prevents eosinophilic lung disease but impairs pathogen clearance|
AE Williams, IR Humphreys, M Cornere, L Edwards, A Rae, T Hussell
Microbes and infection 7 (3), 365-374, 2005
|Interleukin-10 regulates the inflammasome-driven augmentation of inflammatory arthritis and joint destruction|
CJ Greenhill, GW Jones, MA Nowell, Z Newton, AK Harvey, AN Moideen, ...
Arthritis Research & Therapy 16 (5), 419, 2014
|Interleukins 5 and 13 characterize immune responses to respiratory sensitizing acid anhydrides|
RJ Dearman, A Filby, IR Humphreys, I Kimber
Journal of Applied Toxicology 22 (5), 317-325, 2002
|A critical role for ICOS co‐stimulation in immune containment of pulmonary influenza virus infection|
IR Humphreys, L Edwards, RJ Snelgrove, AJ Rae, AJ Coyle, T Hussell
European journal of immunology 36 (11), 2928-2938, 2006
|Prior exposure to live Mycobacterium bovis BCG decreases Cryptococcus neoformans-induced lung eosinophilia in a gamma interferon-dependent manner|
G Walzl, IR Humphreys, BG Marshall, L Edwards, PJM Openshaw, ...
Infection and immunity 71 (6), 3384-3391, 2003